JPWO2020064748A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020064748A5 JPWO2020064748A5 JP2021517252A JP2021517252A JPWO2020064748A5 JP WO2020064748 A5 JPWO2020064748 A5 JP WO2020064748A5 JP 2021517252 A JP2021517252 A JP 2021517252A JP 2021517252 A JP2021517252 A JP 2021517252A JP WO2020064748 A5 JPWO2020064748 A5 JP WO2020064748A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- use according
- ketamine
- sequences
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 43
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 claims 10
- 229960003299 ketamine Drugs 0.000 claims 10
- 239000000843 powder Substances 0.000 claims 10
- 239000012458 free base Substances 0.000 claims 8
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical group C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 claims 6
- 229960000450 esketamine Drugs 0.000 claims 6
- 230000002685 pulmonary effect Effects 0.000 claims 5
- 230000002045 lasting effect Effects 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 210000004072 lung Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- UPXRTVAIJMUAQR-UHFFFAOYSA-N 4-(9h-fluoren-9-ylmethoxycarbonylamino)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid Chemical compound C1C(C(O)=O)N(C(=O)OC(C)(C)C)CC1NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21 UPXRTVAIJMUAQR-UHFFFAOYSA-N 0.000 claims 2
- 239000004606 Fillers/Extenders Substances 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- 230000000996 additive effect Effects 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 229960004184 ketamine hydrochloride Drugs 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 239000003381 stabilizer Substances 0.000 claims 2
- 208000020401 Depressive disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18461615.9 | 2018-09-28 | ||
| EP18461615.9A EP3628313A1 (de) | 2018-09-28 | 2018-09-28 | Ketaminzusammensetzung zur verwendung in einem verfahren zur behandlung von depression mittels pulmonaler verabreichung |
| PCT/EP2019/075735 WO2020064748A1 (en) | 2018-09-28 | 2019-09-24 | Ketamine composition for use in a method of treatment of depression by pulmonary administration |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022502429A JP2022502429A (ja) | 2022-01-11 |
| JPWO2020064748A5 true JPWO2020064748A5 (de) | 2022-09-28 |
| JP7444864B2 JP7444864B2 (ja) | 2024-03-06 |
Family
ID=63713806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021517252A Active JP7444864B2 (ja) | 2018-09-28 | 2019-09-24 | 肺投与によるうつ病の処置方法における使用のためのケタミン組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11925607B2 (de) |
| EP (2) | EP3628313A1 (de) |
| JP (1) | JP7444864B2 (de) |
| KR (1) | KR20210068465A (de) |
| CN (1) | CN113038941A (de) |
| AU (1) | AU2019349624A1 (de) |
| BR (1) | BR112021005687A2 (de) |
| CA (1) | CA3114325A1 (de) |
| EA (1) | EA202190724A1 (de) |
| MX (1) | MX2021003668A (de) |
| WO (1) | WO2020064748A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3505157T3 (da) * | 2017-12-29 | 2022-02-28 | Celon Pharma Sa | Tørpulver-ketaminsammensætning til pulmonal indgivelse ved behandlingsresistent depression |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
| GB0523031D0 (en) * | 2005-11-11 | 2005-12-21 | Yaupon Therapeutics | Enhancement of morphine analgesia by s(-)-norketamine |
| JP2009530385A (ja) | 2006-03-22 | 2009-08-27 | マウント シナイ スクール オブ メディシン | うつ病の治療のためのケタミンの鼻内投与 |
| DE102007009888A1 (de) | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
| GB0908129D0 (en) * | 2009-05-12 | 2009-06-24 | Innovata Ltd | Composition |
| PE20141906A1 (es) * | 2012-03-12 | 2014-12-05 | Janssen Pharmaceutica Nv | Esketamina para el tratamiento de la depresion refractaria al tratamiento o resistente al tratamiento |
| WO2014020155A1 (en) | 2012-08-02 | 2014-02-06 | Clinpharm Reform Gmbh | Oral transmucosal adminstration forms of s-ketamine |
| SG10201802104QA (en) | 2013-03-15 | 2018-05-30 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| SG10201802106TA (en) | 2013-03-15 | 2018-04-27 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| US10098854B2 (en) * | 2014-08-13 | 2018-10-16 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| US20160338977A1 (en) * | 2015-05-20 | 2016-11-24 | Janssen Pharmaceutica Nv | Methods and kits for treating depression |
| CN106562952B (zh) * | 2015-10-09 | 2020-06-09 | 江阴安博生物医药有限公司 | 氯胺酮在治疗重性抑郁障碍中的应用 |
| DK3505157T3 (da) * | 2017-12-29 | 2022-02-28 | Celon Pharma Sa | Tørpulver-ketaminsammensætning til pulmonal indgivelse ved behandlingsresistent depression |
-
2018
- 2018-09-28 EP EP18461615.9A patent/EP3628313A1/de active Pending
-
2019
- 2019-09-24 EP EP19770131.1A patent/EP3856159A1/de active Pending
- 2019-09-24 US US17/281,136 patent/US11925607B2/en active Active
- 2019-09-24 JP JP2021517252A patent/JP7444864B2/ja active Active
- 2019-09-24 MX MX2021003668A patent/MX2021003668A/es unknown
- 2019-09-24 CN CN201980075601.XA patent/CN113038941A/zh active Pending
- 2019-09-24 CA CA3114325A patent/CA3114325A1/en active Pending
- 2019-09-24 WO PCT/EP2019/075735 patent/WO2020064748A1/en unknown
- 2019-09-24 BR BR112021005687-4A patent/BR112021005687A2/pt unknown
- 2019-09-24 EA EA202190724A patent/EA202190724A1/ru unknown
- 2019-09-24 AU AU2019349624A patent/AU2019349624A1/en active Pending
- 2019-09-24 KR KR1020217011554A patent/KR20210068465A/ko unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2203470T3 (es) | Nuevas composiciones de medicamentos a base de bromuro de tiotropio y salmeterol. | |
| JP2019528320A5 (de) | ||
| JP2020073494A5 (de) | ||
| RU2001123923A (ru) | Композиции, включающие формотерол и соль тиотропия | |
| HRP20130835T1 (hr) | Farmaceutske formulacije otopine za davanje kao stlaäśeni inhalat u inhalatoru | |
| RU2010121827A (ru) | Композиции для лечения болезни паркинсона | |
| NZ585857A (en) | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease | |
| JP2014515373A5 (de) | ||
| US10022449B2 (en) | Synergistic antiviral composition and use thereof | |
| JP2020023536A (ja) | Ｃｏｐｄの治療のためのフォルモテロール及びブデソニドの組み合わせ | |
| EP4138832A1 (de) | Produkte zur herstellung und verfahren zur behandlung, linderung oder prävention mikrobieller infektionen | |
| JP2021510682A5 (de) | ||
| CA2838031A1 (en) | Dry powder inhaler compositions comprising umeclidinium | |
| JPWO2020064748A5 (de) | ||
| EP2957552B1 (de) | Vilanterolformulierungen | |
| EP2821062A1 (de) | Neue pharmazeutische Pulverinhalatoren für Atemwege | |
| AU2003292120A1 (en) | New synergistic combination comprising roflumilast and formoterol | |
| AU2020103517A4 (en) | Ibp- nebulizer: intelligent nebulizer for bronchitis patients | |
| US11903925B2 (en) | Compositions for preventing and treating pulmonary injury due to ionizing radiation or cytotoxic drugs | |
| JP2017513866A5 (de) | ||
| AU2013100007A4 (en) | System for treating chronic obstructive pulmonary disease | |
| AU2013100008A4 (en) | Inhalable formulations of glycopyrronium bromide | |
| KR20210068465A (ko) | 폐 투여에 의한 우울증의 치료 방법에 사용하기 위한 케타민 조성물 | |
| IL163736A (en) | Tiotropium containing powdered preparations, method of their preparation and uses thereof for the manufacture of a medicament suitable for inhalation | |
| EP2957551B1 (de) | Trockenpulverformulierungen mit vilanterol |