JPWO2020009747A5 - - Google Patents
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- Publication number
- JPWO2020009747A5 JPWO2020009747A5 JP2020573441A JP2020573441A JPWO2020009747A5 JP WO2020009747 A5 JPWO2020009747 A5 JP WO2020009747A5 JP 2020573441 A JP2020573441 A JP 2020573441A JP 2020573441 A JP2020573441 A JP 2020573441A JP WO2020009747 A5 JPWO2020009747 A5 JP WO2020009747A5
- Authority
- JP
- Japan
- Prior art keywords
- cross
- linking agent
- weight
- monomer mixture
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003431 cross linking reagent Substances 0.000 claims description 105
- 239000000203 mixture Substances 0.000 claims description 72
- 239000000178 monomer Substances 0.000 claims description 64
- 125000000217 alkyl group Chemical group 0.000 claims description 27
- 229920001400 block copolymer Polymers 0.000 claims description 24
- -1 C1- C12alkyl Chemical group 0.000 claims description 22
- 239000001257 hydrogen Substances 0.000 claims description 22
- 229910052739 hydrogen Inorganic materials 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000004971 Cross linker Substances 0.000 claims description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 14
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 13
- 229910052760 oxygen Inorganic materials 0.000 claims description 13
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 9
- 239000001301 oxygen Substances 0.000 claims description 9
- 230000035699 permeability Effects 0.000 claims description 9
- OCAAZRFBJBEVPS-UHFFFAOYSA-N prop-2-enyl carbamate Chemical compound NC(=O)OCC=C OCAAZRFBJBEVPS-UHFFFAOYSA-N 0.000 claims description 9
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims description 9
- 125000005353 silylalkyl group Chemical group 0.000 claims description 8
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 claims description 6
- 125000000262 haloalkenyl group Chemical group 0.000 claims description 6
- 125000001188 haloalkyl group Chemical group 0.000 claims description 6
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims description 6
- 150000002431 hydrogen Chemical group 0.000 claims description 6
- 125000005647 linker group Chemical group 0.000 claims description 6
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000002981 blocking agent Substances 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 4
- 150000003951 lactams Chemical class 0.000 claims description 4
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 3
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical compound OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 claims description 3
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 claims description 3
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 3
- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 claims description 3
- 238000003809 water extraction Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 238000006116 polymerization reaction Methods 0.000 claims description 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 description 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 6
- 238000001723 curing Methods 0.000 description 3
- 239000003085 diluting agent Substances 0.000 description 3
- JWYVGKFDLWWQJX-UHFFFAOYSA-N 1-ethenylazepan-2-one Chemical compound C=CN1CCCCCC1=O JWYVGKFDLWWQJX-UHFFFAOYSA-N 0.000 description 2
- PBGPBHYPCGDFEZ-UHFFFAOYSA-N 1-ethenylpiperidin-2-one Chemical compound C=CN1CCCCC1=O PBGPBHYPCGDFEZ-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical class OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 2
- 239000000017 hydrogel Substances 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 239000003732 agents acting on the eye Substances 0.000 description 1
- 238000011416 infrared curing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940125702 ophthalmic agent Drugs 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862693746P | 2018-07-03 | 2018-07-03 | |
| US62/693,746 | 2018-07-03 | ||
| PCT/US2019/032819 WO2020009747A1 (en) | 2018-07-03 | 2019-05-17 | Water extractable ophthalmic devices |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021529353A JP2021529353A (ja) | 2021-10-28 |
| JPWO2020009747A5 true JPWO2020009747A5 (enExample) | 2022-04-06 |
| JP7368397B2 JP7368397B2 (ja) | 2023-10-24 |
Family
ID=66776887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020573441A Active JP7368397B2 (ja) | 2018-07-03 | 2019-05-17 | 水抽出可能な眼科用デバイス |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11022722B2 (enExample) |
| EP (1) | EP3818401B1 (enExample) |
| JP (1) | JP7368397B2 (enExample) |
| KR (1) | KR102749934B1 (enExample) |
| CN (1) | CN112513681B (enExample) |
| CA (1) | CA3104247A1 (enExample) |
| ES (1) | ES3005558T3 (enExample) |
| WO (1) | WO2020009747A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2726602A1 (es) * | 2018-04-06 | 2019-10-08 | Consejo Superior Investigacion | Hidrogeles basados en vinil-caprolactama |
| TWI685545B (zh) * | 2018-11-30 | 2020-02-21 | 晶碩光學股份有限公司 | 矽水膠組成物、矽水膠鏡片、以及矽水膠鏡片的製造方法 |
| KR102883590B1 (ko) * | 2020-03-19 | 2025-11-10 | 알콘 인코포레이티드 | 내장형 콘택트 렌즈를 위한 고굴절률 실록산 삽입물 재료 |
| KR20220124925A (ko) | 2021-03-04 | 2022-09-14 | 엘지전자 주식회사 | 냉장고 |
| TWI865184B (zh) * | 2023-01-09 | 2024-12-01 | 視陽光學股份有限公司 | 用於隱形眼鏡的組成物與隱形眼鏡 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL285986A (enExample) | 1961-12-27 | |||
| NL128305C (enExample) | 1963-09-11 | |||
| US4113224A (en) | 1975-04-08 | 1978-09-12 | Bausch & Lomb Incorporated | Apparatus for forming optical lenses |
| US4197266A (en) | 1974-05-06 | 1980-04-08 | Bausch & Lomb Incorporated | Method for forming optical lenses |
| US4208506A (en) | 1977-07-25 | 1980-06-17 | Bausch & Lomb Incorporated | Polyparaffinsiloxane shaped article for use in biomedical applications |
| US4228269A (en) * | 1978-06-08 | 1980-10-14 | Wesley-Jessen Inc. | Contact lenses of high gas permeability |
| US4195030A (en) | 1979-01-10 | 1980-03-25 | Bausch & Lomb Incorporated | Preparation of monomeric organosilicon esters |
| US4327203A (en) | 1981-02-26 | 1982-04-27 | Bausch & Lomb Incorporated | Polysiloxane with cycloalkyl modifier composition and biomedical devices |
| US4355147A (en) | 1981-02-26 | 1982-10-19 | Bausch & Lomb Incorporated | Polysiloxane with polycyclic modifier composition and biomedical devices |
| US4555732A (en) | 1984-03-22 | 1985-11-26 | Xerox Corporation | Image sensor correction system |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5271875A (en) | 1991-09-12 | 1993-12-21 | Bausch & Lomb Incorporated | Method for molding lenses |
| US5310779A (en) * | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
| US6020445A (en) | 1997-10-09 | 2000-02-01 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US5998498A (en) * | 1998-03-02 | 1999-12-07 | Johnson & Johnson Vision Products, Inc. | Soft contact lenses |
| JPH11249084A (ja) * | 1998-03-06 | 1999-09-17 | Kuraray Co Ltd | 眼用レンズ材料およびその製造方法 |
| US6244707B1 (en) * | 1998-07-21 | 2001-06-12 | Wesley Jessen Corporation | UV blocking lenses and material containing benzotriazoles and benzophenones |
| US6861123B2 (en) * | 2000-12-01 | 2005-03-01 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogel contact lens |
| ES2214164T3 (es) * | 2001-04-27 | 2009-03-01 | BAUSCH & LOMB INCORPORATED | Reconocimiento y alineacion de patron de iris. |
| US8153344B2 (en) * | 2004-07-16 | 2012-04-10 | Ppg Industries Ohio, Inc. | Methods for producing photosensitive microparticles, aqueous compositions thereof and articles prepared therewith |
| EP1838748B1 (en) * | 2004-12-29 | 2009-03-11 | Bausch & Lomb Incorporated | Polysiloxane prepolymers for biomedical devices |
| US7750079B2 (en) * | 2005-08-09 | 2010-07-06 | Coopervision International Holding Company, Lp | Compositions and methods for producing silicone hydrogel contact lenses |
| TWI443116B (zh) * | 2006-06-15 | 2014-07-01 | Coopervision Int Holding Co Lp | 可溼性矽氧水凝膠隱形眼鏡及相關組合物及方法 |
| EP3424965B1 (en) * | 2007-07-10 | 2020-05-13 | Bausch & Lomb Incorporated | Crosslink agents and its use |
| US8138290B2 (en) | 2008-01-25 | 2012-03-20 | Bausch & Lomb Incorporated | High water content ophthalmic devices |
| CN101482625B (zh) * | 2009-02-13 | 2010-09-29 | 广州科甫眼镜有限公司 | 含透明质酸钠的软性亲水接触镜及其制备方法 |
| US20100315588A1 (en) * | 2009-06-16 | 2010-12-16 | Bausch & Lomb Incorporated | Biomedical devices |
| CN102483467B (zh) * | 2009-07-09 | 2014-01-08 | 博士伦公司 | 包含单烯属不饱和可聚合基团的聚碳硅氧烷单体 |
| US9039174B2 (en) * | 2009-07-09 | 2015-05-26 | Bausch & Lomb Incorporated | Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers |
| US7915323B2 (en) | 2009-07-09 | 2011-03-29 | Bausch & Lamb Incorporated | Mono ethylenically unsaturated polycarbosiloxane monomers |
| EP2483737B1 (en) * | 2009-10-01 | 2016-07-06 | CooperVision International Holding Company, LP | Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses |
| MX354797B (es) * | 2011-02-28 | 2018-03-21 | Coopervision Int Holding Co Lp | Lentes de contacto de hidrogel de silicona dimensionalmente estables. |
| WO2012154268A1 (en) * | 2011-02-28 | 2012-11-15 | Coopervision International Holding Company, Lp | Silicone hydrogel contact lenses |
| KR101771564B1 (ko) * | 2011-03-21 | 2017-09-05 | 모멘티브 퍼포먼스 머티리얼즈 인크. | 가수분해 저항성 카보실록산 연쇄를 포함하는 실론산 모노머, 그 제조방법 및 이를 포함하는 콘텍트 렌즈용 박막 |
| US20120283381A1 (en) * | 2011-05-04 | 2012-11-08 | Ryuta Tamiya | Macroinitiator containing hydrophobic segment |
| US9156934B2 (en) * | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US8937111B2 (en) * | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US8967799B2 (en) * | 2012-12-20 | 2015-03-03 | Bausch & Lomb Incorporated | Method of preparing water extractable silicon-containing biomedical devices |
| KR20140111064A (ko) * | 2013-02-27 | 2014-09-18 | 에스케이이노베이션 주식회사 | 광학필름 |
| US9389336B2 (en) * | 2013-08-02 | 2016-07-12 | Bausch & Lomb Incorporated | Hydrogel monomer mix containing added water |
| CA2940203C (en) | 2014-04-25 | 2019-08-06 | Novartis Ag | Carbosiloxane vinylic monomers |
| CN113480736A (zh) * | 2015-12-15 | 2021-10-08 | 爱尔康公司 | 亲水化的聚二有机硅氧烷乙烯基交联剂以及其用途 |
| US10676575B2 (en) * | 2016-10-06 | 2020-06-09 | Johnson & Johnson Vision Care, Inc. | Tri-block prepolymers and their use in silicone hydrogels |
| KR102759003B1 (ko) * | 2018-05-15 | 2025-01-23 | 보오슈 앤드 롬 인코포레이팃드 | 수 추출 가능한 안과용 디바이스 |
-
2019
- 2019-05-17 WO PCT/US2019/032819 patent/WO2020009747A1/en not_active Ceased
- 2019-05-17 KR KR1020217001437A patent/KR102749934B1/ko active Active
- 2019-05-17 ES ES19729122T patent/ES3005558T3/es active Active
- 2019-05-17 US US16/415,281 patent/US11022722B2/en active Active
- 2019-05-17 JP JP2020573441A patent/JP7368397B2/ja active Active
- 2019-05-17 CN CN201980044304.9A patent/CN112513681B/zh active Active
- 2019-05-17 CA CA3104247A patent/CA3104247A1/en active Pending
- 2019-05-17 EP EP19729122.2A patent/EP3818401B1/en active Active
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