JPWO2019231271A5 - - Google Patents
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- Publication number
- JPWO2019231271A5 JPWO2019231271A5 JP2020566834A JP2020566834A JPWO2019231271A5 JP WO2019231271 A5 JPWO2019231271 A5 JP WO2019231271A5 JP 2020566834 A JP2020566834 A JP 2020566834A JP 2020566834 A JP2020566834 A JP 2020566834A JP WO2019231271 A5 JPWO2019231271 A5 JP WO2019231271A5
- Authority
- JP
- Japan
- Prior art keywords
- present
- activation
- novel heterocyclic
- stat3 protein
- suppresses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004495 STAT3 Transcription Factor Human genes 0.000 description 2
- 108010017324 STAT3 Transcription Factor Proteins 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 150000002391 heterocyclic compounds Chemical class 0.000 description 2
- 102100019388 SOAT1 Human genes 0.000 description 1
- 101700025022 SOAT1 Proteins 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 101710028406 satA Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2018-0062450 | 2018-05-31 | ||
| KR20180062450 | 2018-05-31 | ||
| PCT/KR2019/006554 WO2019231271A1 (en) | 2018-05-31 | 2019-05-31 | Heterocyclic derivatives and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021525752A JP2021525752A (ja) | 2021-09-27 |
| JPWO2019231271A5 true JPWO2019231271A5 (zh) | 2022-03-31 |
Family
ID=68698337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566834A Pending JP2021525752A (ja) | 2018-05-31 | 2019-05-31 | 複素環誘導体及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210155594A1 (zh) |
| EP (1) | EP3802495A4 (zh) |
| JP (1) | JP2021525752A (zh) |
| KR (1) | KR102229471B1 (zh) |
| CN (1) | CN112204010B (zh) |
| TW (1) | TW202016076A (zh) |
| WO (1) | WO2019231271A1 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110105237B (zh) * | 2019-06-06 | 2021-12-24 | 东北师范大学 | 一种β-偕二氟叠氮化合物及其制备和应用 |
| US11648254B2 (en) | 2021-03-02 | 2023-05-16 | Kumquat Biosciences Inc. | Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling |
| CN113845476B (zh) * | 2021-11-08 | 2024-04-30 | 中国药科大学 | 一种喹诺酮衍生物及其制备方法和用途 |
| CN114315802B (zh) * | 2021-12-14 | 2023-06-16 | 西安医学院 | 一种喹唑啉含氮杂环衍生物及制备方法和用途 |
| US11912708B2 (en) | 2022-04-20 | 2024-02-27 | Kumquat Biosciences Inc. | Macrocyclic heterocycles and uses thereof |
| EP4296674A1 (en) | 2022-06-20 | 2023-12-27 | Université Toulouse III - Paul Sabatier | Innovative molecules decreasing virulence of mycobacterium for the treatment of tuberculosis |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1689753A4 (en) | 2003-12-04 | 2010-07-07 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| GB0420719D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| WO2008086462A2 (en) * | 2007-01-11 | 2008-07-17 | Wyeth | AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF β-CANTENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS |
| EP2014663A1 (de) | 2007-07-12 | 2009-01-14 | Bayer Schering Pharma AG | Thienopyrimidylamine als Modulatoren des EP2-Rezeptors |
| DE102007032739A1 (de) | 2007-07-13 | 2009-01-15 | Merck Patent Gmbh | Chinazolinamidderivate |
| JP5650529B2 (ja) | 2008-07-10 | 2015-01-07 | 一般社団法人ファルマバレープロジェクト支援機構 | キノリンカルボキサミド誘導体を有効成分とするｓｔａｔ３阻害剤 |
| EP2331530B8 (en) | 2008-09-26 | 2013-12-25 | National Health Research Institutes | Fused multicyclic compounds as protein kinase inhibitors |
| DK2396307T3 (en) * | 2009-02-11 | 2015-01-12 | Merck Patent Gmbh | NOVEL AMINO-azaheterocyclic carboxamides |
| WO2012079079A1 (en) * | 2010-12-10 | 2012-06-14 | President And Fellows Of Harvard College | Production of induced pluripotent stem cells |
| WO2014145512A2 (en) * | 2013-03-15 | 2014-09-18 | President And Fellows Of Harvard College | Potent small molecule inhibitors of autophagy, and methods of use thereof |
| CN111315723A (zh) * | 2017-08-31 | 2020-06-19 | 艾伯维公司 | 膜外核苷酸焦磷酸酶-磷酸二酯酶1(enpp-1)抑制剂及其用途 |
-
2019
- 2019-05-30 TW TW108118755A patent/TW202016076A/zh unknown
- 2019-05-31 US US17/058,209 patent/US20210155594A1/en active Pending
- 2019-05-31 CN CN201980035635.6A patent/CN112204010B/zh active Active
- 2019-05-31 KR KR1020190064288A patent/KR102229471B1/ko active IP Right Grant
- 2019-05-31 WO PCT/KR2019/006554 patent/WO2019231271A1/en unknown
- 2019-05-31 EP EP19812552.8A patent/EP3802495A4/en active Pending
- 2019-05-31 JP JP2020566834A patent/JP2021525752A/ja active Pending
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