JPWO2019226603A5 - - Google Patents

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JPWO2019226603A5
JPWO2019226603A5 JP2020564923A JP2020564923A JPWO2019226603A5 JP WO2019226603 A5 JPWO2019226603 A5 JP WO2019226603A5 JP 2020564923 A JP2020564923 A JP 2020564923A JP 2020564923 A JP2020564923 A JP 2020564923A JP WO2019226603 A5 JPWO2019226603 A5 JP WO2019226603A5
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JP
Japan
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mir
rna
premirna
polynucleotide according
polynucleotide
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JP2020564923A
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English (en)
Japanese (ja)
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JP2021524245A5 (https=
JP7545726B2 (ja
JP2021524245A (ja
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Publication of JPWO2019226603A5 publication Critical patent/JPWO2019226603A5/ja
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JP2020564923A 2018-05-22 2019-05-21 tRNA/プレmiRNA組成物およびがん治療における使用 Active JP7545726B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862674939P 2018-05-22 2018-05-22
US62/674,939 2018-05-22
PCT/US2019/033232 WO2019226603A1 (en) 2018-05-22 2019-05-21 Trna/pre-mirna compositions and use in treating cancer

Publications (4)

Publication Number Publication Date
JP2021524245A JP2021524245A (ja) 2021-09-13
JP2021524245A5 JP2021524245A5 (https=) 2022-05-23
JPWO2019226603A5 true JPWO2019226603A5 (https=) 2022-05-23
JP7545726B2 JP7545726B2 (ja) 2024-09-05

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US (1) US11946049B2 (https=)
EP (1) EP3796920A4 (https=)
JP (1) JP7545726B2 (https=)
WO (1) WO2019226603A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11702657B2 (en) 2018-04-20 2023-07-18 The Regents Of The University Of California TRNA/pre-miRNA compositions and methods for treating hepatocellular carcinoma
GB201919021D0 (en) 2019-12-20 2020-02-05 Reneuron Ltd Nucleic acid constructs for delivering polynucleotides into exosomes
CN110946872B (zh) * 2019-12-30 2022-11-04 北京大学深圳医院 miR-4491在制备治疗乳腺癌的药物中的应用
AU2021255583A1 (en) * 2020-04-14 2022-11-10 Flagship Pioneering Innovations Vi, Llc Trem compositions and uses thereof
CN114058697B (zh) * 2020-07-29 2023-08-18 四川大学华西医院 检测外泌体miR-6774-3p或miR-6776-5p的试剂的用途
US20230407297A1 (en) * 2020-11-03 2023-12-21 The Regents Of The University Of California Bioengineered wnt5a therapeutics for advanced cancers
WO2023164285A1 (en) * 2022-02-28 2023-08-31 Northwestern University DISE-INDUCING sRNA-POLYPLEXES AND sRNA-LIPOPOLYPLEXES AND METHODS OF USING THE SAME TO TREAT CANCER
CN115323057A (zh) * 2022-09-01 2022-11-11 浙江医院 肺癌治疗疗效相关的生物标志物
CN115896295A (zh) * 2022-12-30 2023-04-04 中国科学技术大学 辅助诊断胆囊炎或预测胆囊炎合并肝损伤的miRNA标志物
CN117126938A (zh) * 2023-10-08 2023-11-28 常州市第一人民医院 一种用于诊断膜性肾病的生物标志物及其应用方法
WO2025155837A1 (en) * 2024-01-19 2025-07-24 Massachusetts Institute Of Technology Modular microrna expression from self-replicating rna (replicons)
CN121406635A (zh) * 2024-05-08 2026-01-27 西安艾领克生物科技有限公司 一种利用活性tRNA在大肠杆菌中嵌合表达重组小RNA的方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
US9340799B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College MRNA-sensing switchable gRNAs
EP3160980B1 (en) 2014-05-28 2020-05-20 The Regents of the University of California HYBRID tRNA/pre-miRNA MOLECULES AND METHODS OF USE
WO2016153880A2 (en) * 2015-03-23 2016-09-29 The Regents Of The University Of California Methods for detection of rnase activity
US11702657B2 (en) * 2018-04-20 2023-07-18 The Regents Of The University Of California TRNA/pre-miRNA compositions and methods for treating hepatocellular carcinoma

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