JPWO2019198692A5 - - Google Patents
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- Publication number
- JPWO2019198692A5 JPWO2019198692A5 JP2020555239A JP2020555239A JPWO2019198692A5 JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5 JP 2020555239 A JP2020555239 A JP 2020555239A JP 2020555239 A JP2020555239 A JP 2020555239A JP WO2019198692 A5 JPWO2019198692 A5 JP WO2019198692A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxo
- chloro
- cyclohexyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862654628P | 2018-04-09 | 2018-04-09 | |
| US62/654,628 | 2018-04-09 | ||
| PCT/JP2019/015392 WO2019198692A1 (en) | 2018-04-09 | 2019-04-09 | Fused cyclic urea derivatives as crhr2 antagonist |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521142A JP2021521142A (ja) | 2021-08-26 |
| JPWO2019198692A5 true JPWO2019198692A5 (ko) | 2023-05-19 |
| JP7357932B2 JP7357932B2 (ja) | 2023-10-10 |
Family
ID=68164246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555239A Active JP7357932B2 (ja) | 2018-04-09 | 2019-04-09 | Ｃｒｈｒ２拮抗薬としての縮合環状尿素誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11802120B2 (ko) |
| EP (1) | EP3774739B1 (ko) |
| JP (1) | JP7357932B2 (ko) |
| KR (1) | KR102590854B1 (ko) |
| CN (1) | CN111868037B (ko) |
| BR (1) | BR112020020708A8 (ko) |
| CA (1) | CA3094609A1 (ko) |
| ES (1) | ES2917634T3 (ko) |
| MX (1) | MX2020010568A (ko) |
| TW (1) | TWI822754B (ko) |
| WO (1) | WO2019198692A1 (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202140480A (zh) * | 2020-01-15 | 2021-11-01 | 日商拉夸里亞創藥股份有限公司 | 作為crhr2拮抗劑之螺雜環衍生物 |
| EP3901152A1 (en) * | 2020-04-23 | 2021-10-27 | F. Hoffmann-La Roche AG | Kv3 enhancers for the treatment of cognitive disorders |
| EP4222142A4 (en) * | 2020-09-30 | 2024-10-16 | Raqualia Pharma Inc | 3-HYDROXYOXINDOLE DERIVATIVES USEFUL AS CRHR2 ANTAGONISTS |
| CN117279923A (zh) * | 2021-04-27 | 2023-12-22 | 南京明德新药研发有限公司 | 六元杂芳并脲环的衍生物及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999057103A1 (fr) | 1998-04-30 | 1999-11-11 | Nippon Chemiphar Co., Ltd. | Derive d'imidazole condense et agent therapeutique permettant de traiter une maladie du foie |
| PL366934A1 (en) | 2001-04-30 | 2005-02-07 | Glaxo Group Limited | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) |
| JP2004533465A (ja) * | 2001-06-12 | 2004-11-04 | グラクソ グループ リミテッド | コルチコトロピン放出因子アンタゴニスト |
| JP2007161585A (ja) | 2004-06-25 | 2007-06-28 | Taisho Pharmaceut Co Ltd | 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体 |
| JP2008517060A (ja) * | 2004-10-19 | 2008-05-22 | エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド | Ｃｒｆ受容体アンタゴニストおよびその製法 |
| WO2007149938A2 (en) | 2006-06-21 | 2007-12-27 | The Salk Institute Biological Studies | Methods for promoting hair growth |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| JP5748777B2 (ja) * | 2010-02-02 | 2015-07-15 | ノバルティス アーゲー | Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体 |
| US20150094310A1 (en) * | 2012-04-23 | 2015-04-02 | Holsboermaschmeyer Neurochemie Gmbh | Crhr1 antagonists for use in the treatment of patients having crh overactivity |
-
2019
- 2019-04-09 CA CA3094609A patent/CA3094609A1/en active Pending
- 2019-04-09 JP JP2020555239A patent/JP7357932B2/ja active Active
- 2019-04-09 ES ES19785626T patent/ES2917634T3/es active Active
- 2019-04-09 MX MX2020010568A patent/MX2020010568A/es unknown
- 2019-04-09 CN CN201980019725.6A patent/CN111868037B/zh active Active
- 2019-04-09 WO PCT/JP2019/015392 patent/WO2019198692A1/en active Application Filing
- 2019-04-09 EP EP19785626.3A patent/EP3774739B1/en active Active
- 2019-04-09 TW TW108112345A patent/TWI822754B/zh active
- 2019-04-09 BR BR112020020708A patent/BR112020020708A8/pt unknown
- 2019-04-09 KR KR1020207030243A patent/KR102590854B1/ko active IP Right Grant
- 2019-04-09 US US17/046,196 patent/US11802120B2/en active Active
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