JPWO2019183186A5 - - Google Patents
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- JPWO2019183186A5 JPWO2019183186A5 JP2020550632A JP2020550632A JPWO2019183186A5 JP WO2019183186 A5 JPWO2019183186 A5 JP WO2019183186A5 JP 2020550632 A JP2020550632 A JP 2020550632A JP 2020550632 A JP2020550632 A JP 2020550632A JP WO2019183186 A5 JPWO2019183186 A5 JP WO2019183186A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862646432P | 2018-03-22 | 2018-03-22 | |
| US62/646,432 | 2018-03-22 | ||
| PCT/US2019/023111 WO2019183186A1 (en) | 2018-03-22 | 2019-03-20 | Heterocyclic compounds comprising pyridine useful as modulators of il-12, il-23 and/or ifn alpha responses |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021518389A JP2021518389A (ja) | 2021-08-02 |
| JP2021518389A5 JP2021518389A5 (https=) | 2022-03-31 |
| JPWO2019183186A5 true JPWO2019183186A5 (https=) | 2022-03-31 |
| JP7485609B2 JP7485609B2 (ja) | 2024-05-16 |
Family
ID=66001366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550632A Active JP7485609B2 (ja) | 2018-03-22 | 2019-03-20 | ＩＬ－１２、ＩＬ－２３および／またはＩＦＮα応答のモジュレーターとして有用なピリジン含有ヘテロ環式化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11597721B2 (https=) |
| EP (1) | EP3768667B1 (https=) |
| JP (1) | JP7485609B2 (https=) |
| KR (1) | KR102741437B1 (https=) |
| CN (1) | CN111936486B (https=) |
| ES (1) | ES2944733T3 (https=) |
| WO (1) | WO2019183186A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3118094A1 (en) * | 2018-10-30 | 2020-05-07 | Bristol-Myers Squibb Company | Amide-substituted heterocyclic compounds for the treatment of conditions related to the modulation of il-12, il-23 and/or ifn-alpha |
| AU2020209216A1 (en) | 2019-01-18 | 2021-08-26 | Astrazeneca Ab | PCSK9 inhibitors and methods of use thereof |
| SG11202107614PA (en) | 2019-01-18 | 2021-08-30 | Astrazeneca Ab | Pcsk9 inhibitors and methods of use thereof |
| DK4038063T3 (da) * | 2020-03-11 | 2024-05-21 | Beijing Innocare Pharma Tech Co Ltd | Heterocykliske forbindelser til inhibering af tyk2-aktiviteter |
| US20230295119A1 (en) | 2020-04-14 | 2023-09-21 | Gossamer Bio Services, Inc. | Substituted pyridines for the treatment of inflammatory diseases |
| WO2022135430A1 (en) | 2020-12-22 | 2022-06-30 | InventisBio Co., Ltd. | Heteroaryl compounds, preparation methods and uses thereof |
| EP4308556A4 (en) | 2021-03-16 | 2025-02-19 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Amino heteroaryl compounds and compositions |
| CN115141149A (zh) * | 2021-03-30 | 2022-10-04 | 浙江文达医药科技有限公司 | 作为tyk2假激酶结构域抑制剂的杂环化合物及合成方法和用途 |
| CN116888125B (zh) * | 2021-04-07 | 2024-04-12 | 上海齐鲁制药研究中心有限公司 | Tyk2抑制剂及其用途 |
| AU2022268464B2 (en) * | 2021-05-04 | 2025-04-17 | Shanghai Zheye Biotechnology Co. Ltd. | Nitrogen-containing heterocyclic pyridine compound |
| US20240317718A1 (en) * | 2021-05-14 | 2024-09-26 | Bristol-Myers Squibb Company | Substituted heterocyclic compounds |
| TWI825800B (zh) * | 2021-06-22 | 2023-12-11 | 大陸商南京明德新藥研發有限公司 | 亞磺醯亞胺類化合物及其應用 |
| WO2023284869A1 (zh) * | 2021-07-15 | 2023-01-19 | 南京明德新药研发有限公司 | 含硫/磷的芳基类化合物及其应用 |
| EP4387964A1 (en) * | 2021-08-21 | 2024-06-26 | Relay Therapeutics, Inc. | Jak2 inhibitors and methods of use thereof |
| WO2023064223A1 (en) | 2021-10-11 | 2023-04-20 | Gossamer Bio Services, Inc. | Tri-substituted pyridines |
| JP2024539280A (ja) | 2021-10-25 | 2024-10-28 | カイメラ セラピューティクス， インコーポレイテッド | Ｔｙｋ２分解剤およびそれらの使用 |
| EP4448514A4 (en) | 2021-12-16 | 2025-10-29 | Lynk Pharmaceuticals Co Ltd | TYK2 INHIBITORS AND ASSOCIATED COMPOSITIONS AND PROCESSES |
| EP4206196A1 (en) | 2021-12-29 | 2023-07-05 | Almirall S.A. | Pyrimidine substituted derivatives as tyk2 inhibitors |
| WO2024020221A1 (en) * | 2022-07-21 | 2024-01-25 | Arvinas Operations, Inc. | Modulators of tyk2 proteolysis and associated methods of use |
| WO2024131882A1 (zh) * | 2022-12-22 | 2024-06-27 | 南京明德新药研发有限公司 | 一种吡啶多取代化合物的盐型、晶型及其制备方法 |
| CN120607493B (zh) * | 2025-06-04 | 2026-04-24 | 江西科技师范大学 | 一种含嘧啶结构的酰胺类化合物及其在制备tyk2 jh2激酶抑制剂中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013052393A1 (en) | 2011-10-05 | 2013-04-11 | Merck Sharp & Dohme Corp. | 3-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| WO2013104573A1 (en) | 2012-01-10 | 2013-07-18 | F. Hoffmann-La Roche Ag | Pyridazine amide compounds and their use as syk inhibitors |
| US9315494B2 (en) | 2012-11-08 | 2016-04-19 | Bristol-Myers Squibb Company | Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFNα responses |
| MY194668A (en) * | 2012-11-08 | 2022-12-12 | Bristol Myers Squibb Co | Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn() responses |
| CN110267964B (zh) | 2016-12-13 | 2022-05-03 | 百时美施贵宝公司 | 作为IL-12、IL-23及/或IFNα响应调节剂的经取代的杂芳基氧化膦化合物 |
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2019
- 2019-03-20 EP EP19715330.7A patent/EP3768667B1/en active Active
- 2019-03-20 WO PCT/US2019/023111 patent/WO2019183186A1/en not_active Ceased
- 2019-03-20 US US16/982,937 patent/US11597721B2/en active Active
- 2019-03-20 KR KR1020207029906A patent/KR102741437B1/ko active Active
- 2019-03-20 CN CN201980020946.5A patent/CN111936486B/zh active Active
- 2019-03-20 JP JP2020550632A patent/JP7485609B2/ja active Active
- 2019-03-20 ES ES19715330T patent/ES2944733T3/es active Active