JPWO2019183186A5 - - Google Patents
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- JPWO2019183186A5 JPWO2019183186A5 JP2020550632A JP2020550632A JPWO2019183186A5 JP WO2019183186 A5 JPWO2019183186 A5 JP WO2019183186A5 JP 2020550632 A JP2020550632 A JP 2020550632A JP 2020550632 A JP2020550632 A JP 2020550632A JP WO2019183186 A5 JPWO2019183186 A5 JP WO2019183186A5
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- JP
- Japan
- Prior art keywords
- present application
- invention described
- application
- present
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Claims (1)
- 本願明細書に記載の発明。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862646432P | 2018-03-22 | 2018-03-22 | |
| US62/646,432 | 2018-03-22 | ||
| PCT/US2019/023111 WO2019183186A1 (en) | 2018-03-22 | 2019-03-20 | Heterocyclic compounds comprising pyridine useful as modulators of il-12, il-23 and/or ifn alpha responses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021518389A JP2021518389A (ja) | 2021-08-02 |
| JPWO2019183186A5 true JPWO2019183186A5 (ja) | 2022-03-31 |
| JP7485609B2 JP7485609B2 (ja) | 2024-05-16 |
Family
ID=66001366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550632A Active JP7485609B2 (ja) | 2018-03-22 | 2019-03-20 | ＩＬ－１２、ＩＬ－２３および／またはＩＦＮα応答のモジュレーターとして有用なピリジン含有ヘテロ環式化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11597721B2 (ja) |
| EP (1) | EP3768667B1 (ja) |
| JP (1) | JP7485609B2 (ja) |
| KR (1) | KR20200135425A (ja) |
| CN (1) | CN111936486B (ja) |
| ES (1) | ES2944733T3 (ja) |
| WO (1) | WO2019183186A1 (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210086674A (ko) * | 2018-10-30 | 2021-07-08 | 브리스톨-마이어스 스큅 컴퍼니 | Il-12, il-23 및/또는 ifn-알파의 조정과 관련된 상태의 치료를 위한 아미드-치환된 헤테로시클릭 화합물 |
| HRP20240643T1 (hr) * | 2020-03-11 | 2024-08-02 | Beijing Innocare Pharma Tech Co., Ltd. | Heterociklički spojevi za inhibiciju aktivnosti tyk2 |
| US20230295119A1 (en) | 2020-04-14 | 2023-09-21 | Gossamer Bio Services, Inc. | Substituted pyridines for the treatment of inflammatory diseases |
| CN116888125B (zh) * | 2021-04-07 | 2024-04-12 | 上海齐鲁制药研究中心有限公司 | Tyk2抑制剂及其用途 |
| CN117136058A (zh) * | 2021-05-04 | 2023-11-28 | 上海喆邺生物科技有限公司 | 一类含氮杂环吡啶类化合物 |
| BR112023026964A2 (pt) * | 2021-06-22 | 2024-03-12 | Medshine Discovery Inc | Composto de sulfoximina e uso do mesmo |
| CN117794911A (zh) * | 2021-07-15 | 2024-03-29 | 南京明德新药研发有限公司 | 含硫/磷的芳基类化合物及其应用 |
| EP4387964A1 (en) * | 2021-08-21 | 2024-06-26 | Relay Therapeutics, Inc. | Jak2 inhibitors and methods of use thereof |
| WO2023064223A1 (en) | 2021-10-11 | 2023-04-20 | Gossamer Bio Services, Inc. | Tri-substituted pyridines |
| AU2022378463A1 (en) | 2021-10-25 | 2024-05-09 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
| CN118401516A (zh) * | 2021-12-16 | 2024-07-26 | 凌科药业(杭州)有限公司 | Tyk2抑制剂及其组合物和方法 |
| EP4206196A1 (en) | 2021-12-29 | 2023-07-05 | Almirall S.A. | Pyrimidine substituted derivatives as tyk2 inhibitors |
| WO2024020221A1 (en) * | 2022-07-21 | 2024-01-25 | Arvinas Operations, Inc. | Modulators of tyk2 proteolysis and associated methods of use |
| WO2024131882A1 (zh) * | 2022-12-22 | 2024-06-27 | 南京明德新药研发有限公司 | 一种吡啶多取代化合物的盐型、晶型及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2763975B1 (en) * | 2011-10-05 | 2016-04-06 | Merck Sharp & Dohme Corp. | 3-pyridyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors |
| CA2860547A1 (en) | 2012-01-10 | 2013-07-18 | Johannes Cornelius Hermann | Pyridazine amide compounds and their use as syk inhibitors |
| MA38072A1 (fr) * | 2012-11-08 | 2016-07-29 | Bristol Myers Squibb Co | Composés hétérocycliques substitués par amide, utiles comme modulateurs d'il-12, il-23 et/ou de réponses à l'ifn? |
| AU2013341185B2 (en) | 2012-11-08 | 2017-07-13 | Bristol-Myers Squibb Company | Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFNalpha responses |
| WO2018111787A1 (en) | 2016-12-13 | 2018-06-21 | Bristol-Myers Squibb Company | Phosphine oxide alkyl amide substituted heteroaryl compounds as modulators of il-12, il-23, and/or ifn alpha responses |
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2019
- 2019-03-20 JP JP2020550632A patent/JP7485609B2/ja active Active
- 2019-03-20 KR KR1020207029906A patent/KR20200135425A/ko not_active Application Discontinuation
- 2019-03-20 EP EP19715330.7A patent/EP3768667B1/en active Active
- 2019-03-20 WO PCT/US2019/023111 patent/WO2019183186A1/en active Application Filing
- 2019-03-20 US US16/982,937 patent/US11597721B2/en active Active
- 2019-03-20 ES ES19715330T patent/ES2944733T3/es active Active
- 2019-03-20 CN CN201980020946.5A patent/CN111936486B/zh active Active