JPWO2019178296A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2019178296A5
JPWO2019178296A5 JP2020548709A JP2020548709A JPWO2019178296A5 JP WO2019178296 A5 JPWO2019178296 A5 JP WO2019178296A5 JP 2020548709 A JP2020548709 A JP 2020548709A JP 2020548709 A JP2020548709 A JP 2020548709A JP WO2019178296 A5 JPWO2019178296 A5 JP WO2019178296A5
Authority
JP
Japan
Prior art keywords
cells
cell
reprogramming
aged
aging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020548709A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021518331A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/022149 external-priority patent/WO2019178296A1/en
Publication of JP2021518331A publication Critical patent/JP2021518331A/ja
Publication of JPWO2019178296A5 publication Critical patent/JPWO2019178296A5/ja
Priority to JP2023172587A priority Critical patent/JP2024016026A/ja
Pending legal-status Critical Current

Links

JP2020548709A 2018-03-13 2019-03-13 細胞加齢の反転のための一過性細胞リプログラミング Pending JP2021518331A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023172587A JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862642538P 2018-03-13 2018-03-13
US62/642,538 2018-03-13
PCT/US2019/022149 WO2019178296A1 (en) 2018-03-13 2019-03-13 Transient cellular reprogramming for reversal of cell aging

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023172587A Division JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Publications (2)

Publication Number Publication Date
JP2021518331A JP2021518331A (ja) 2021-08-02
JPWO2019178296A5 true JPWO2019178296A5 (zh) 2023-03-02

Family

ID=67907311

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020548709A Pending JP2021518331A (ja) 2018-03-13 2019-03-13 細胞加齢の反転のための一過性細胞リプログラミング
JP2023172587A Pending JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023172587A Pending JP2024016026A (ja) 2018-03-13 2023-10-04 細胞加齢の反転のための一過性細胞リプログラミング

Country Status (13)

Country Link
US (1) US20210010034A1 (zh)
EP (1) EP3764795A4 (zh)
JP (2) JP2021518331A (zh)
KR (1) KR20200131301A (zh)
CN (1) CN112154210A (zh)
AU (1) AU2019235861A1 (zh)
BR (1) BR112020018602A2 (zh)
CA (1) CA3093823A1 (zh)
CR (1) CR20200462A (zh)
IL (1) IL277265A (zh)
MX (1) MX2020009491A (zh)
SG (1) SG11202008839WA (zh)
WO (1) WO2019178296A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020206187A1 (en) * 2019-04-02 2020-10-08 Centagen, Inc Engineered system of stem cell rejuvenation to treat aging and disease
WO2021026362A1 (en) 2019-08-07 2021-02-11 Edifice Health, Inc. Treatment of prevention of cardiovascular disease
TWI789724B (zh) * 2020-03-20 2023-01-11 台灣粒線體應用技術股份有限公司 粒線體用於治療及/或預防肌腱受損或其相關疾病之用途
WO2021211382A1 (en) * 2020-04-13 2021-10-21 Edifice Health, Inc. Compounds and methods for modifying iage
WO2022115492A1 (en) * 2020-11-24 2022-06-02 Lyell Immunopharma, Inc. Methods for making, compositions comprising, and methods of using rejuvenated t cells
WO2023288287A2 (en) * 2021-07-15 2023-01-19 Turn Biotechnologies, Inc. Synthetic, persistent rna constructs and methods of use for cell rejuvenation and for treatment
WO2023288285A1 (en) 2021-07-15 2023-01-19 Turn Biotechnologies, Inc. Polycistronic expression vectors
WO2023061485A1 (zh) * 2021-10-14 2023-04-20 北京干细胞与再生医学研究院 年轻化骨骼肌肉细胞及其制备方法和应用
WO2023201097A1 (en) 2022-04-15 2023-10-19 Turn Biotechnologies, Inc. Methods and compositions for immune cell rejuvenation and therapies using rejuvenated immune cells
WO2023215857A2 (en) * 2022-05-06 2023-11-09 President And Fellows Of Harvard College Treatments for age-related cellular dysfunction
WO2024012503A1 (zh) * 2022-07-12 2024-01-18 南京瑞初医药有限公司 组合物及其使用方法
WO2024012502A1 (zh) * 2022-07-12 2024-01-18 南京瑞初医药有限公司 组合物及其使用方法
WO2024155957A1 (en) 2023-01-19 2024-07-25 Altos Labs, Inc. Use of regeneration factors in organ transplantation
CN116426469B (zh) * 2023-06-07 2023-09-08 北京大学口腔医学院 LAP2α在间充质干细胞成脂向分化中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2578685T (lt) * 2005-08-23 2019-06-10 The Trustees Of The University Of Pennsylvania Rnr, apimančios modifikuotus nukleozidus ir jų panaudojimo būdai
US9012219B2 (en) * 2005-08-23 2015-04-21 The Trustees Of The University Of Pennsylvania RNA preparations comprising purified modified RNA for reprogramming cells
US8669048B2 (en) * 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
DK3287525T3 (da) * 2009-12-07 2020-01-20 Univ Pennsylvania RNA-præparater omfattende oprenset modificeret RNA til omprogrammering af celler
US9057053B2 (en) * 2010-01-19 2015-06-16 The Board Of Trustees Of The Leland Stanford Junior University Direct conversion of cells to cells of other lineages
US8962331B2 (en) * 2010-02-01 2015-02-24 The Board Of Trustees Of The Leland Stanford Junior University Method of making induced pluripotent stem cell from adipose stem cells using minicircle DNA vectors
EP3415616B1 (en) * 2011-04-08 2024-05-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for rejuvenating cells
US10155929B2 (en) * 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
WO2015120225A1 (en) * 2014-02-10 2015-08-13 The Board Of Trustees Of The Leland Stanford Junior University ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA
EP3180443A1 (en) * 2014-08-13 2017-06-21 Timmons, James Archibald Healthcare diagnostic
WO2016112111A1 (en) * 2015-01-08 2016-07-14 The Board Of Trustees Of The Leland Stanford Junior University Factors and cells that provide for induction of bone, bone marrow, and cartilage
JP2018501809A (ja) * 2015-01-14 2018-01-25 メモリアル スローン−ケタリング キャンサー センター 年齢改変細胞および年齢改変細胞を作製するための方法
EP3132809A1 (en) * 2015-08-21 2017-02-22 Bioskinco GmbH Composition and products comprising senescent cells for use in tissue regeneration
US11298380B2 (en) * 2018-01-02 2022-04-12 Khloris Biosciences, Inc. IPSC-based vaccine as a prophylactic and therapeutic treatment for cancer
WO2020167648A1 (en) * 2019-02-15 2020-08-20 The Board Of Trustees Of The Leland Stanford Junior University Generation of type 1 regulatory t cells through transcription factor targeting
US20220175899A1 (en) * 2019-04-11 2022-06-09 The Board Of Trustees Of The Leland Stanford Junior University Cytotoxic t lymphocytes specific for mutated forms of epidermal growth factor receptor for use in treating cancer
US20230045590A1 (en) * 2019-12-23 2023-02-09 The Board Of Trustees Of The Leland Stanford Junior University Genetically corrected cells for therapeutic use

Similar Documents

Publication Publication Date Title
JP2021518331A (ja) 細胞加齢の反転のための一過性細胞リプログラミング
AU2022200207B2 (en) Compositions and methods for induced tissue regeneration in mammalian species
CN104937095B (zh) 肾细胞群及其用途
US20100135970A1 (en) Methods for Reprogramming Adult Somatic Cells and Uses Thereof
US20200199541A1 (en) Blood vessel organoid, methods of producing and using said organoids
JPWO2019178296A5 (zh)
CN102459576A (zh) 用于调节干细胞的组合物和方法及其应用
CN109152799A (zh) 胰腺干细胞及其用途
Sarkar et al. Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Kenigsberg et al. Genome engineering of human urine-derived stem cells to express lactoferrin and deoxyribonuclease
RU2801316C2 (ru) Транзиентное клеточное перепрограммирование для обращения старения клетки
Shao et al. Human muscle stem/progenitor cells are bi-potential adult stem cells
Sarkar Transient Reprogramming for Multifaceted Reversal of Aging Phenotypes
US20110052551A1 (en) Cardiac myocyte morphogenic compositions and methods of use therefor
Zhang et al. Exploring the Presence of Female Germline Stem Cells in Rats and Mice
US20150056172A1 (en) Methods and compositions using fgf-8 to enhance cardiac regeneration and attenuate adverse cardiac remodeling