JPWO2019173503A5 - - Google Patents
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- Publication number
- JPWO2019173503A5 JPWO2019173503A5 JP2020570410A JP2020570410A JPWO2019173503A5 JP WO2019173503 A5 JPWO2019173503 A5 JP WO2019173503A5 JP 2020570410 A JP2020570410 A JP 2020570410A JP 2020570410 A JP2020570410 A JP 2020570410A JP WO2019173503 A5 JPWO2019173503 A5 JP WO2019173503A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- spik
- antibody
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023127022A JP7539536B2 (ja) | 2018-03-06 | 2023-08-03 | セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862639345P | 2018-03-06 | 2018-03-06 | |
| US62/639,345 | 2018-03-06 | ||
| US201862639850P | 2018-03-07 | 2018-03-07 | |
| US62/639,850 | 2018-03-07 | ||
| PCT/US2019/020999 WO2019173503A2 (en) | 2018-03-06 | 2019-03-06 | Serine protease inhibitor kazal (spik) compositions and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023127022A Division JP7539536B2 (ja) | 2018-03-06 | 2023-08-03 | セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021515597A JP2021515597A (ja) | 2021-06-24 |
| JP2021515597A5 JP2021515597A5 (https=) | 2022-03-15 |
| JPWO2019173503A5 true JPWO2019173503A5 (https=) | 2022-03-15 |
| JP7328261B2 JP7328261B2 (ja) | 2023-08-16 |
Family
ID=65818672
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020570410A Active JP7328261B2 (ja) | 2018-03-06 | 2019-03-06 | セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 |
| JP2023127022A Active JP7539536B2 (ja) | 2018-03-06 | 2023-08-03 | セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023127022A Active JP7539536B2 (ja) | 2018-03-06 | 2023-08-03 | セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12180301B2 (https=) |
| EP (1) | EP3762426A2 (https=) |
| JP (2) | JP7328261B2 (https=) |
| CN (2) | CN112292401A (https=) |
| CA (1) | CA3093295A1 (https=) |
| WO (1) | WO2019173503A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112292401A (zh) | 2018-03-06 | 2021-01-29 | 英凯尔生物科技有限责任公司 | 丝氨酸蛋白酶抑制剂Kazal(SPIK)组合物和方法 |
| EP3996816A1 (en) * | 2019-07-08 | 2022-05-18 | Imcare Biotech, LLC | Anti-serine protease inhibitor kazal (spik) antibodies, immunoconjugates, and methods of use |
| WO2021050217A1 (en) | 2019-09-11 | 2021-03-18 | Imcare Biotech, Llc. | Epitopes of anti-serine protease inhibitor kazal (spik) antibodies |
| EP4211468A4 (en) * | 2020-09-11 | 2024-10-09 | Glympse Bio, Inc. | DETECTION OF EX VIVO PROTEASE ACTIVITY FOR DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT OF DISEASES |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| KR100332254B1 (ko) | 1993-10-01 | 2002-09-27 | 데이꼬꾸 조끼 세이야꾸 가부시키가이샤 | 신규인펩티드유도체 |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| US6248564B1 (en) | 1997-08-29 | 2001-06-19 | Harvard University | Mutant MHC class I molecules |
| US20040018194A1 (en) | 2000-11-28 | 2004-01-29 | Francisco Joseph A. | Recombinant anti-CD30 antibodies and uses thereof |
| US6884869B2 (en) | 2001-04-30 | 2005-04-26 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| CA2467242A1 (en) | 2001-11-20 | 2003-05-30 | Seattle Genetics, Inc. | Treatment of immunological disorders using anti-cd30 antibodies |
| AU2003294210A1 (en) | 2002-07-31 | 2004-05-04 | Seattle Genetics, Inc | Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders |
| EP1391213A1 (en) | 2002-08-21 | 2004-02-25 | Boehringer Ingelheim International GmbH | Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| WO2007030560A2 (en) * | 2005-09-08 | 2007-03-15 | Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine | Identification of modulators of serine protease inhibitor kazal and their use as anti-cancer and anti-viral agents |
| CA2703140A1 (en) | 2007-10-25 | 2009-04-30 | Viventia Biotech Inc. | Antibodies against a cancer-associated epitope of variant hnrnpg and uses thereof |
| MX2011010265A (es) | 2009-04-01 | 2011-10-11 | Genentech Inc | Anticuerpos anti-fcrh5 e inmunoconjugados y metodos de uso. |
| US20110206697A1 (en) * | 2010-02-19 | 2011-08-25 | The Regents Of The University Of Michigan | Spink1 targeted therapy |
| US20140308657A1 (en) * | 2010-12-09 | 2014-10-16 | Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine | Serine protease inhibitor kazal antibodies |
| CN105968209B (zh) | 2011-04-19 | 2021-08-03 | 美国政府(由卫生和人类服务部的部长所代表) | 对磷脂酰肌醇蛋白聚糖3特异的人单克隆抗体及其用途 |
| WO2014127200A1 (en) | 2013-02-15 | 2014-08-21 | Immunomedics, Inc. | Chimeric and humanized anti-histone antibodies |
| WO2015164757A1 (en) | 2014-04-25 | 2015-10-29 | Oregon Health & Science University | Methods of viral neutralizing antibody epitope mapping |
| AU2017239637A1 (en) | 2016-03-29 | 2018-11-15 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| EP4219559A3 (en) * | 2017-12-22 | 2023-10-18 | Jounce Therapeutics, Inc. | Antibodies for lilrb2 |
| CN112292401A (zh) | 2018-03-06 | 2021-01-29 | 英凯尔生物科技有限责任公司 | 丝氨酸蛋白酶抑制剂Kazal(SPIK)组合物和方法 |
| CN109678950B (zh) | 2019-01-08 | 2022-05-10 | 灏灵赛奥（天津）生物科技有限公司 | spink1抗原、能够特异性结合spink1的抗体及其功能片段及其应用和产品 |
| CN109776679B (zh) * | 2019-01-08 | 2022-06-17 | 灏灵赛奥（天津）生物科技有限公司 | 一种丝氨酸蛋白酶抑制因子spink1的抗体、其制备方法和应用 |
| EP3996816A1 (en) | 2019-07-08 | 2022-05-18 | Imcare Biotech, LLC | Anti-serine protease inhibitor kazal (spik) antibodies, immunoconjugates, and methods of use |
| MX2022012752A (es) * | 2020-04-15 | 2023-01-16 | Voyager Therapeutics Inc | Compuestos de union a tau. |
-
2019
- 2019-03-06 CN CN201980017414.6A patent/CN112292401A/zh active Pending
- 2019-03-06 WO PCT/US2019/020999 patent/WO2019173503A2/en not_active Ceased
- 2019-03-06 US US16/978,634 patent/US12180301B2/en active Active
- 2019-03-06 JP JP2020570410A patent/JP7328261B2/ja active Active
- 2019-03-06 CN CN202510180099.6A patent/CN120005029A/zh active Pending
- 2019-03-06 EP EP19712403.5A patent/EP3762426A2/en active Pending
- 2019-03-06 CA CA3093295A patent/CA3093295A1/en active Pending
-
2023
- 2023-08-03 JP JP2023127022A patent/JP7539536B2/ja active Active
-
2024
- 2024-11-20 US US18/953,861 patent/US20250353927A1/en active Pending
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