JPWO2019167874A1 - Apoa4に対するモノクローナル抗体、免疫学的測定方法及び測定用キット - Google Patents

Apoa4に対するモノクローナル抗体、免疫学的測定方法及び測定用キット Download PDF

Info

Publication number
JPWO2019167874A1
JPWO2019167874A1 JP2020503487A JP2020503487A JPWO2019167874A1 JP WO2019167874 A1 JPWO2019167874 A1 JP WO2019167874A1 JP 2020503487 A JP2020503487 A JP 2020503487A JP 2020503487 A JP2020503487 A JP 2020503487A JP WO2019167874 A1 JPWO2019167874 A1 JP WO2019167874A1
Authority
JP
Japan
Prior art keywords
antibody
apoa4
amino acid
seq
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020503487A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019167874A5 (https=
Inventor
曜子 井田
曜子 井田
小原 隆
隆 小原
英美子 湯本
英美子 湯本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co Ltd filed Critical Eisai R&D Management Co Ltd
Publication of JPWO2019167874A1 publication Critical patent/JPWO2019167874A1/ja
Publication of JPWO2019167874A5 publication Critical patent/JPWO2019167874A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04Sandwich assay format

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
JP2020503487A 2018-02-27 2019-02-25 Apoa4に対するモノクローナル抗体、免疫学的測定方法及び測定用キット Pending JPWO2019167874A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018033113 2018-02-27
JP2018033113 2018-02-27
PCT/JP2019/007033 WO2019167874A1 (ja) 2018-02-27 2019-02-25 Apoa4に対するモノクローナル抗体、免疫学的測定方法及び測定用キット

Publications (2)

Publication Number Publication Date
JPWO2019167874A1 true JPWO2019167874A1 (ja) 2021-03-18
JPWO2019167874A5 JPWO2019167874A5 (https=) 2022-02-25

Family

ID=67805043

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020503487A Pending JPWO2019167874A1 (ja) 2018-02-27 2019-02-25 Apoa4に対するモノクローナル抗体、免疫学的測定方法及び測定用キット

Country Status (4)

Country Link
US (1) US11327078B2 (https=)
EP (1) EP3760641A4 (https=)
JP (1) JPWO2019167874A1 (https=)
WO (1) WO2019167874A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114773466B (zh) * 2020-11-26 2023-08-29 江苏荃信生物医药股份有限公司 一种抗人白介素23及包含其的试剂盒及其检测方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT412129B (de) 2001-07-26 2004-09-27 Vitateq Biotechnology Gmbh Verfahren zur diagnose von nierenschädigungen im frühstadium durch messen der apoa-iv-menge in einer serum- oder plasmaprobe
AT502227B1 (de) 2005-08-08 2007-08-15 Vitateq Biotechnology Gmbh Verfahren zur diagnose von tumoren
FR2893136A1 (fr) 2005-11-10 2007-05-11 Sanofi Aventis Sa Procedes de diagnostic de maladies hepatiques et de criblage de molecules pour le traitement de ces maladies
DK2102239T3 (da) * 2006-11-30 2012-05-29 Res Dev Foundation Forbedrede immunoglobulin-biblioteker
AR086250A1 (es) * 2011-05-05 2013-11-27 Hoffmann La Roche Polipeptido de fusion presentador de una secuencia de aminoacidos y utilizacion del mismo
US9534058B2 (en) * 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
SG11201604664PA (en) * 2013-12-12 2016-07-28 Stemcentrx Inc Novel anti-dpep3 antibodies and methods of use
CA2939941A1 (en) * 2014-02-21 2015-08-27 Abbvie Stemcentrx Llc Anti-dll3 antibodies and drug conjugates for use in melanoma
TW201617368A (zh) * 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗mfi2抗體及使用方法
AU2016284871B2 (en) * 2015-06-23 2022-09-29 Innate Pharma Multispecific NK engager proteins
MX383464B (es) * 2015-07-13 2025-03-14 Cytomx Therapeutics Inc Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos.
US20200341014A1 (en) * 2016-03-18 2020-10-29 Eisai R&D Management Co., Ltd. PD Marker of Hepatocyte Growth Factor (HGF)
JP6786958B2 (ja) 2016-08-26 2020-11-18 株式会社リコー 出力装置、情報提供システム、音波出力方法、及びプログラム

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THERAPEUTIC APHERESIS AND DIALYSIS, 2010, VOL. 14, NO. 3, PP. 341-348, JPN6023003824, ISSN: 0005118770 *

Also Published As

Publication number Publication date
US20210055300A1 (en) 2021-02-25
US11327078B2 (en) 2022-05-10
EP3760641A1 (en) 2021-01-06
WO2019167874A1 (ja) 2019-09-06
EP3760641A4 (en) 2021-11-24

Similar Documents

Publication Publication Date Title
AU2015254257B2 (en) Anti-MUC1 antibody or antigen-binding fragment of same, and use thereof
US11372001B2 (en) Anti-human IgG4 monoclonal antibody and methods of making and using same
US20110076700A1 (en) Anti-crp antibody and utilization of the same
EP4047017B1 (en) Monoclonal antibody, measurement reagent for cytokeratin 18 fragment, reagent kit, and measurement method
KR101338517B1 (ko) 인간 간-카르복실에스터라제 1을 특이적으로 인식하는 단일클론 항체, 상기 항체를 생산하는 하이브리도마 세포주 및 이의 용도
US11327078B2 (en) Monoclonal antibody against APOA4, immunological measurement method, and kit for measurement
WO2017188312A1 (ja) 抗医薬品抗体の測定方法
JP7807250B2 (ja) Dupan-2抗原の測定方法、測定試薬及び測定キット
JP7803727B2 (ja) Dupan-2抗原の測定方法、測定試薬及び測定キット
US20250296994A1 (en) Monoclonal antibody, reagent for measuring crtac1b, reagent kit, and method for measuring crtac1b
CN116143929B (zh) 抗重组人凝血因子VIIa-Fc融合蛋白的抗体及其应用
JP7222501B2 (ja) 末端シアル酸残基がα2,3結合でガラクトースに結合した糖鎖に特異的に結合するモノクローナル抗体、及び、末端シアル酸残基がα2,3結合でガラクトースに結合した糖鎖の測定方法
JP6407990B2 (ja) アウグリン免疫学的検定
JP5448424B2 (ja) ヒトIgGのFcを含有するタンパク質の測定試薬
WO2026081529A1 (zh) Il-1r2在鉴定对象免疫状态中的应用
EP2495564B1 (en) 5.9 kDa PEPTIDE IMMUNOASSAY METHOD
JP4803943B2 (ja) 肝細胞増殖因子活性化因子阻害因子−1に対する抗体とその用途
CN116003592A (zh) 针对人血小板生成素的抗体
JP2018080167A (ja) 肝性リパーゼに対する抗体及びその利用
HK40031146A (en) Anti-human igg4 monoclonal antibody and human igg4 assay reagent using said antibody
JP2019210211A (ja) ウシプロカルシトニンを特異的に認識する抗体、その抗原結合断片、および、その使用
JP2007254428A (ja) 天然で未変性のcdtに対する抗体、抗体の製造方法、ハイブリドーマ、及び免疫測定方法
JP2005314397A (ja) 抗コンドロモジュリン−1特異的抗体及びその利用

Legal Events

Date Code Title Description
RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20200706

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20200706

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220216

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220216

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230207

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20230801