JPWO2019155474A5 - - Google Patents
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- Publication number
- JPWO2019155474A5 JPWO2019155474A5 JP2020542989A JP2020542989A JPWO2019155474A5 JP WO2019155474 A5 JPWO2019155474 A5 JP WO2019155474A5 JP 2020542989 A JP2020542989 A JP 2020542989A JP 2020542989 A JP2020542989 A JP 2020542989A JP WO2019155474 A5 JPWO2019155474 A5 JP WO2019155474A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- slamf6
- cell population
- var3
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims 17
- 101000633786 Homo sapiens SLAM family member 6 Proteins 0.000 claims 15
- 210000001744 T-lymphocyte Anatomy 0.000 claims 15
- 206010028980 Neoplasm Diseases 0.000 claims 9
- 201000011510 cancer Diseases 0.000 claims 9
- 102100029197 SLAM family member 6 Human genes 0.000 claims 8
- 102000046571 human SLAMF6 Human genes 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 239000002243 precursor Substances 0.000 claims 5
- 210000004881 tumor cell Anatomy 0.000 claims 5
- 229940030156 cell vaccine Drugs 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 210000004443 dendritic cell Anatomy 0.000 claims 3
- 229940029030 dendritic cell vaccine Drugs 0.000 claims 3
- 229940030325 tumor cell vaccine Drugs 0.000 claims 3
- 201000001441 melanoma Diseases 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862629129P | 2018-02-12 | 2018-02-12 | |
| US62/629,129 | 2018-02-12 | ||
| PCT/IL2019/050163 WO2019155474A1 (en) | 2018-02-12 | 2019-02-11 | Modulation of slamf6 splice variants for cancer therapy |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021516668A JP2021516668A (ja) | 2021-07-08 |
| JPWO2019155474A5 true JPWO2019155474A5 (https=) | 2022-02-21 |
| JP2021516668A5 JP2021516668A5 (https=) | 2022-02-21 |
| JP7458318B2 JP7458318B2 (ja) | 2024-03-29 |
Family
ID=67548888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542989A Active JP7458318B2 (ja) | 2018-02-12 | 2019-02-11 | 癌治療のためのｓｌａｍｆ６スプライスバリアントの調節 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11834487B2 (https=) |
| EP (1) | EP3752252A4 (https=) |
| JP (1) | JP7458318B2 (https=) |
| IL (1) | IL276117B1 (https=) |
| WO (1) | WO2019155474A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL267614A (en) | 2019-06-24 | 2019-09-26 | Lotem Michal | Nucleic acids to modulate SLAMF6 isoforms |
| CN117867107A (zh) * | 2023-11-24 | 2024-04-12 | 南通大学附属医院 | 一种构建肠癌诊断和预后相关的甲基化位点的诊断模型方法及其诊断标志物slamf6 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US7479269B2 (en) | 1988-11-23 | 2009-01-20 | Genetics Institute, Llc | Methods for selectively enriching TH1 and TH2 cells |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5719867A (en) | 1995-06-30 | 1998-02-17 | Scientific-Atlanta, Inc. | Plural telephony channel baseband signal demodulator for a broadband communications system |
| CA2454185A1 (en) | 2001-07-19 | 2003-01-30 | Innate Pharma | Ntb-a, a surface molecule involved in natural killer cells activity |
| MXPA04001986A (es) | 2001-08-29 | 2004-06-07 | Genentech Inc | Composiciones y metodos para el tratamiento de enfermedades relacionadas a la inmunidad. |
| JP2005206478A (ja) | 2004-01-20 | 2005-08-04 | Kirin Brewery Co Ltd | 樹状細胞膜分子−ＩｇＦｃ融合ポリペプチドまたはそれに対する抗体を含む医薬組成物 |
| WO2005124346A1 (en) | 2004-05-17 | 2005-12-29 | The Board Of Trustees Of The University Of Illinois | 4-1bb receptors are expressed on regulatory t-cells |
| PL1642905T3 (pl) | 2004-10-02 | 2009-04-30 | Immatics Biotechnologies Gmbh | Epitopy immunogenicznych komórek pomocniczych T z antygenów guzów ludzkich oraz sposoby immunoterapeutyczne wykorzystujące te epitopy |
| EP1871911A2 (en) | 2005-04-07 | 2008-01-02 | Chiron Corporation | Cancer-related genes (prlr) |
| EP1916302A4 (en) | 2005-08-17 | 2009-10-21 | Takara Bio Inc | PROCESS FOR THE PRODUCTION OF LYMPHOCYTES |
| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| US7847067B2 (en) | 2006-08-28 | 2010-12-07 | ARCA Biopharma | Antibodies to NTB-A |
| WO2012129201A1 (en) | 2011-03-22 | 2012-09-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| CN105431449B (zh) | 2013-04-05 | 2021-08-24 | 港大科桥有限公司 | 新的pd1同种型及其用于加强免疫应答的用途 |
| US10287354B2 (en) | 2013-12-20 | 2019-05-14 | Novartis Ag | Regulatable chimeric antigen receptor |
| CA2935903A1 (en) | 2014-01-09 | 2015-07-16 | Hadasit Medical Research Services And Development Ltd. | Improved cell compositions and methods for cancer therapy |
| DK3317301T3 (da) | 2015-07-29 | 2021-06-28 | Immutep Sas | Kombinationsterapier omfattende antistofmolekyler mod lag-3 |
| WO2017075478A2 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures |
| NL2017267B1 (en) | 2016-07-29 | 2018-02-01 | Aduro Biotech Holdings Europe B V | Anti-pd-1 antibodies |
| US20190262399A1 (en) | 2016-09-07 | 2019-08-29 | The Broad Institute, Inc. | Compositions and methods for evaluating and modulating immune responses |
| IL267614A (en) | 2019-06-24 | 2019-09-26 | Lotem Michal | Nucleic acids to modulate SLAMF6 isoforms |
-
2019
- 2019-02-11 IL IL276117A patent/IL276117B1/en unknown
- 2019-02-11 WO PCT/IL2019/050163 patent/WO2019155474A1/en not_active Ceased
- 2019-02-11 JP JP2020542989A patent/JP7458318B2/ja active Active
- 2019-02-11 EP EP19751265.0A patent/EP3752252A4/en active Pending
- 2019-02-11 US US16/968,967 patent/US11834487B2/en active Active
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