JPWO2018234492A5 - - Google Patents
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- Publication number
- JPWO2018234492A5 JPWO2018234492A5 JP2019571042A JP2019571042A JPWO2018234492A5 JP WO2018234492 A5 JPWO2018234492 A5 JP WO2018234492A5 JP 2019571042 A JP2019571042 A JP 2019571042A JP 2019571042 A JP2019571042 A JP 2019571042A JP WO2018234492 A5 JPWO2018234492 A5 JP WO2018234492A5
- Authority
- JP
- Japan
- Prior art keywords
- modified protein
- asparaginase
- amino acid
- seq
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023030460A JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762523061P | 2017-06-21 | 2017-06-21 | |
| EP17177237.9A EP3418383A1 (en) | 2017-06-21 | 2017-06-21 | Modified l-asparaginase |
| EP17177237.9 | 2017-06-21 | ||
| US62/523,061 | 2017-06-21 | ||
| US15/671,086 | 2017-08-07 | ||
| US15/671,086 US10174302B1 (en) | 2017-06-21 | 2017-08-07 | Modified L-asparaginase |
| PCT/EP2018/066647 WO2018234492A1 (en) | 2017-06-21 | 2018-06-21 | L-ASPARAGINASE MODIFIED |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023030460A Division JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020528743A JP2020528743A (ja) | 2020-10-01 |
| JPWO2018234492A5 true JPWO2018234492A5 (https=) | 2025-05-08 |
| JP2020528743A5 JP2020528743A5 (https=) | 2025-05-08 |
| JP7808424B2 JP7808424B2 (ja) | 2026-01-29 |
Family
ID=64737515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571042A Active JP7808424B2 (ja) | 2017-06-21 | 2018-06-21 | 修飾されたｌ－アスパラギナーゼ |
| JP2023030460A Active JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023030460A Active JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP3642340B1 (https=) |
| JP (2) | JP7808424B2 (https=) |
| KR (1) | KR102727396B1 (https=) |
| CN (1) | CN111315878B (https=) |
| AU (1) | AU2018287145B2 (https=) |
| BR (1) | BR112019027479A2 (https=) |
| CA (1) | CA3068100A1 (https=) |
| DK (1) | DK3642340T3 (https=) |
| ES (1) | ES2979314T3 (https=) |
| FI (1) | FI3642340T3 (https=) |
| IL (1) | IL271504B2 (https=) |
| MX (2) | MX2019015502A (https=) |
| SA (2) | SA519410870B1 (https=) |
| SG (1) | SG11201912625QA (https=) |
| WO (1) | WO2018234492A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2877539T3 (es) | 2015-12-22 | 2021-11-17 | Xl Protein Gmbh | Acidos nucleicos que codifican secuencias repetitivas de aminoácidos ricos en residuos de prolina y alanina que tienen bajas secuencias de nucleótidos repetitivas |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| IL271504B2 (en) * | 2017-06-21 | 2024-05-01 | Jazz Pharmaceuticals Ireland Ltd | Modified l-asparaginase |
| WO2019101308A1 (en) * | 2017-11-22 | 2019-05-31 | Merz Pharma Gmbh & Co. Kgaa | Novel recombinant botulinum toxin with increased duration of effect |
| CN113473980A (zh) | 2019-03-01 | 2021-10-01 | 弗拉梅尔爱尔兰有限公司 | 在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物 |
| JP2022553399A (ja) * | 2019-10-25 | 2022-12-22 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 組換えｌ－アスパラギナーゼ |
| US20220227805A1 (en) * | 2020-12-23 | 2022-07-21 | Jazz Pharmaceuticals Ireland Ltd. | Methods of purifying charge-shielded fusion proteins |
| WO2022211829A1 (en) | 2021-03-30 | 2022-10-06 | Jazz Pharmaceuticals Ireland Ltd. | Dosing of recombinant l-asparaginase |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| WO2024015529A2 (en) | 2022-07-14 | 2024-01-18 | Jazz Pharmaceuticals Ireland Ltd. | Combination therapies involving l-asparaginase |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| GB8519753D0 (en) * | 1985-08-06 | 1985-09-11 | Health Lab Service Board | Production of 1-asparaginase |
| GB9017002D0 (en) * | 1990-08-02 | 1990-09-19 | Health Lab Service Board | Improved method for the purification of erwina l-asparaginase |
| US7985548B2 (en) | 2006-03-03 | 2011-07-26 | The United States Of America As Represented By The Department Of Health And Human Services | Materials and methods directed to asparagine synthetase and asparaginase therapies |
| US7666652B2 (en) * | 2007-03-09 | 2010-02-23 | Novozymes A/S | Asparaginases |
| ATE502114T1 (de) | 2007-06-21 | 2011-04-15 | Univ Muenchen Tech | Biologisch aktive proteine mit erhöhter in-vivo- und/oder in-vitro-stabilität |
| WO2011003633A1 (en) * | 2009-07-06 | 2011-01-13 | Alize Pharma Ii | Pegylated l-asparaginase |
| WO2011144756A1 (en) | 2010-05-21 | 2011-11-24 | Xl-Protein Gmbh | Biosynthetic proline/alanine random coil polypeptides and their uses |
| CN117462693A (zh) | 2012-02-27 | 2024-01-30 | 阿穆尼克斯运营公司 | Xten缀合组合物和制造其的方法 |
| IL271504B2 (en) | 2017-06-21 | 2024-05-01 | Jazz Pharmaceuticals Ireland Ltd | Modified l-asparaginase |
-
2018
- 2018-06-21 IL IL271504A patent/IL271504B2/en unknown
- 2018-06-21 EP EP18731853.0A patent/EP3642340B1/en active Active
- 2018-06-21 BR BR112019027479-0A patent/BR112019027479A2/pt unknown
- 2018-06-21 DK DK18731853.0T patent/DK3642340T3/da active
- 2018-06-21 JP JP2019571042A patent/JP7808424B2/ja active Active
- 2018-06-21 EP EP22204187.3A patent/EP4180525A1/en active Pending
- 2018-06-21 CA CA3068100A patent/CA3068100A1/en active Pending
- 2018-06-21 AU AU2018287145A patent/AU2018287145B2/en active Active
- 2018-06-21 SG SG11201912625QA patent/SG11201912625QA/en unknown
- 2018-06-21 CN CN201880054251.4A patent/CN111315878B/zh active Active
- 2018-06-21 KR KR1020207002029A patent/KR102727396B1/ko active Active
- 2018-06-21 MX MX2019015502A patent/MX2019015502A/es unknown
- 2018-06-21 WO PCT/EP2018/066647 patent/WO2018234492A1/en not_active Ceased
- 2018-06-21 FI FIEP18731853.0T patent/FI3642340T3/fi active
- 2018-06-21 ES ES18731853T patent/ES2979314T3/es active Active
-
2019
- 2019-12-18 MX MX2024015050A patent/MX2024015050A/es unknown
- 2019-12-21 SA SA519410870A patent/SA519410870B1/ar unknown
- 2019-12-21 SA SA522433360A patent/SA522433360B1/ar unknown
-
2023
- 2023-02-28 JP JP2023030460A patent/JP7770352B2/ja active Active
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