JPWO2018221430A1 - 観察容器及び微小粒子計測装置 - Google Patents
観察容器及び微小粒子計測装置 Download PDFInfo
- Publication number
- JPWO2018221430A1 JPWO2018221430A1 JP2019522204A JP2019522204A JPWO2018221430A1 JP WO2018221430 A1 JPWO2018221430 A1 JP WO2018221430A1 JP 2019522204 A JP2019522204 A JP 2019522204A JP 2019522204 A JP2019522204 A JP 2019522204A JP WO2018221430 A1 JPWO2018221430 A1 JP WO2018221430A1
- Authority
- JP
- Japan
- Prior art keywords
- light
- observation container
- plate portion
- imaging
- observation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010419 fine particle Substances 0.000 title claims abstract description 59
- 238000005259 measurement Methods 0.000 title claims description 58
- 238000003384 imaging method Methods 0.000 claims abstract description 153
- 239000011859 microparticle Substances 0.000 claims description 70
- 230000003287 optical effect Effects 0.000 claims description 13
- 238000005192 partition Methods 0.000 claims description 9
- 238000013459 approach Methods 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 4
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 230000035699 permeability Effects 0.000 claims description 2
- 239000007788 liquid Substances 0.000 abstract description 20
- 238000004458 analytical method Methods 0.000 description 30
- 230000007246 mechanism Effects 0.000 description 11
- 230000004048 modification Effects 0.000 description 10
- 238000012986 modification Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 6
- 235000013601 eggs Nutrition 0.000 description 6
- 230000003595 spectral effect Effects 0.000 description 6
- 238000011156 evaluation Methods 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 238000001228 spectrum Methods 0.000 description 5
- 230000004308 accommodation Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000005284 excitation Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 229910000530 Gallium indium arsenide Inorganic materials 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 239000006143 cell culture medium Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000010801 machine learning Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 238000003909 pattern recognition Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 229910052714 tellurium Inorganic materials 0.000 description 1
- PORWMNRCUJJQNO-UHFFFAOYSA-N tellurium atom Chemical compound [Te] PORWMNRCUJJQNO-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B11/00—Measuring arrangements characterised by the use of optical techniques
- G01B11/24—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0854—Double walls
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/144—Imaging characterised by its optical setup
- G01N2015/1445—Three-dimensional imaging, imaging in different image planes, e.g. under different angles or at different depths, e.g. by a relative motion of sample and detector, for instance by tomography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1497—Particle shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0378—Shapes
- G01N2021/0382—Frustoconical, tapered cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6497—Miscellaneous applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Microscoopes, Condenser (AREA)
- Length Measuring Devices By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
Abstract
Description
(1)撮像装置による撮像の対象となる微小粒子を含む試料が収容され、互いに交差する第1板部及び第2板部により構成された底部を有し、
前記第1板部は、互いに平行な平面である第1内面と第1外面とを有し、
前記第2板部は、互いに平行な平面である第2内面と第2外面とを有し、
前記第1板部及び前記第2板部の両方において、前記微小粒子の観察に用いられる光の波長に対して透光性を有する領域を有する、観察容器、
(2)撮像装置による撮像の対象となる微小粒子を含む試料が収容され、互いに交差する第1板部及び第2板部により構成された底部を有し、
前記第1板部は、第1内面と平面からなる第1外面とを有し、
前記第2板部は、第2内面と平面からなる第2外面とを有し、
前記第1外面と前記第2外面との交線は、直線状に伸び、
前記第1外面と前記第2外面との交線に対して垂直な断面において、前記第1内面と前記第1外面とは互いに平行であると共に、前記第2内面と前記第2外面とは互いに平行であり、
前記第1板部の厚み及び前記第2板部の厚みは、それぞれ前記第1外面と前記第2外面との交線に沿って変化し、
前記第1内面と前記第2内面との交線は、前記底部の中央部において前記第1外面と前記第2外面との交線に近付くと共に、その曲率半径は、1mm〜10mmであり、
前記第1板部及び前記第2板部の両方において、前記微小粒子の観察に用いられる光の波長に対して透光性を有する領域を有する、観察容器、
である。
最初に本願発明の実施態様を列記して説明する。
本発明に係る観察容器及び微小粒子測定装置の具体例を、以下に図面を参照しつつ説明する。なお、本発明はこれらの例示に限定されるものではなく、特許請求の範囲によって示され、特許請求の範囲と均等の意味及び範囲内での全ての変更が含まれることが意図される。
Claims (14)
- 撮像装置による撮像の対象となる微小粒子を含む試料が収容され、互いに交差する第1板部及び第2板部により構成された底部を有し、
前記第1板部は、互いに平行な平面である第1内面と第1外面とを有し、
前記第2板部は、互いに平行な平面である第2内面と第2外面とを有し、
前記第1板部及び前記第2板部の両方において、前記微小粒子の観察に用いられる光の波長に対して透光性を有する領域を有する、観察容器。 - 前記第1板部及び前記第2板部は、互いに直交するように配置される、請求項1に記載の観察容器。
- 前記透光性を有する領域は、350nm〜2000nmの波長帯の光を透過する、請求項1又は2に記載の観察容器。
- 撮像装置による撮像の対象となる微小粒子を含む試料が収容され、互いに交差する第1板部及び第2板部により構成された底部を有し、
前記第1板部は、第1内面と平面からなる第1外面とを有し、
前記第2板部は、第2内面と平面からなる第2外面とを有し、
前記第1外面と前記第2外面との交線は、直線状に伸び、
前記第1外面と前記第2外面との交線に対して垂直な断面において、前記第1内面と前記第1外面とは互いに平行であると共に、前記第2内面と前記第2外面とは互いに平行であり、
前記第1板部の厚み及び前記第2板部の厚みは、それぞれ前記第1外面と前記第2外面との交線に沿って変化し、
前記第1内面と前記第2内面との交線は、前記底部の中央部において前記第1外面と前記第2外面との交線に近付くと共に、その曲率半径は、1mm〜10mmであり、
前記第1板部及び前記第2板部の両方において、前記微小粒子の観察に用いられる光の波長に対して透光性を有する領域を有する、観察容器。 - 前記透光性を有する領域は、350nm〜2000nmの波長帯の光を透過する、請求項4に記載の観察容器。
- 前記微小粒子を含む試料を収容する収容部を複数有する、請求項1〜5のいずれか一項に記載の観察容器。
- 前記複数の収容部は、前記収容部の側壁よりも低い隔壁により区画されていて、前記隔壁よりも上側で前記複数の収容部はつながっている、請求項6に記載の観察容器。
- 前記微小粒子を含む試料を収容する収容部の上方を覆うとともに、前記収容部内と外部の通気性を確保する蓋部を有する、請求項1〜7のいずれか一項に記載の観察容器。
- 底面が平坦であって、前記観察容器を自立可能に支持する支持部を有する、請求項1〜8のいずれか一項に記載の観察容器。
- 請求項1〜9のいずれか一項に記載の観察容器と、
前記試料に対して測定光を照射する光源部と、
前記光源部から照射された測定光によって生じる前記微小粒子の像を、前記観察容器の前記第1板部及び前記第2板部のそれぞれの外側で撮像する複数の撮像部と、
を有し、
前記観察容器のうち前記撮像部が受光する光の光路上となる領域は、前記微小粒子の観察に用いられる光の波長に対して透光性を有する、微小粒子計測装置。 - 前記撮像部は、前記受光する光の光軸が前記撮像部の前に設けられる前記第1板部又は前記第2板部に対して直交する位置に設けられる、請求項10に記載の微小粒子計測装置。
- 前記光源部から照射される光は350nm〜2000nmの波長帯の一部を含む、請求項10又は11に記載の微小粒子計測装置。
- 前記光源部は、前記微小粒子を挟んで前記複数の撮像部に対向する位置に複数設けられる、請求項10〜12のいずれか一項に記載の微小粒子計測装置。
- 前記撮像部は、前記光源部から照射された測定光に対して前記微小粒子が発した蛍光を撮像する、請求項10〜12のいずれか一項に記載の微小粒子計測装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2017105795 | 2017-05-29 | ||
JP2017105795 | 2017-05-29 | ||
PCT/JP2018/020257 WO2018221430A1 (ja) | 2017-05-29 | 2018-05-28 | 観察容器及び微小粒子計測装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2018221430A1 true JPWO2018221430A1 (ja) | 2020-04-09 |
JP7070566B2 JP7070566B2 (ja) | 2022-05-18 |
Family
ID=64454690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019522204A Active JP7070566B2 (ja) | 2017-05-29 | 2018-05-28 | 観察容器及び微小粒子計測装置 |
Country Status (5)
Country | Link |
---|---|
US (1) | US11333596B2 (ja) |
EP (1) | EP3633350A4 (ja) |
JP (1) | JP7070566B2 (ja) |
CN (2) | CN208795640U (ja) |
WO (1) | WO2018221430A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3770580A4 (en) * | 2018-03-20 | 2021-05-19 | Sumitomo Electric Industries, Ltd. | FINE PARTICLE MEASUREMENT DEVICE |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0843400A (ja) * | 1994-07-29 | 1996-02-16 | Olympus Optical Co Ltd | 特異的結合反応を応用した分析方法及び装置並びにこれに用いられる反応容器 |
JPH10253624A (ja) * | 1997-03-13 | 1998-09-25 | Toa Medical Electronics Co Ltd | 粒子測定装置 |
JPH11183358A (ja) * | 1997-12-25 | 1999-07-09 | Kowa Co | 蛍光粒子撮像用容器 |
JP2001133397A (ja) * | 1999-11-05 | 2001-05-18 | Fujirebio Inc | 検体の検査装置 |
JP2009002674A (ja) * | 2007-06-19 | 2009-01-08 | Furukawa Electric Co Ltd:The | 微細粒子のスクリーニング装置および微細粒子のスクリーニング方法 |
WO2010122346A1 (en) * | 2009-04-23 | 2010-10-28 | Avacta Limited | Cuvette and optical method |
EP2450690A1 (en) * | 2010-11-04 | 2012-05-09 | Qiagen GmbH | Vessel for Accurate Optical Measurements |
JP2013170861A (ja) * | 2012-02-20 | 2013-09-02 | Dainippon Screen Mfg Co Ltd | 撮像装置、試料保持プレートおよび撮像方法 |
WO2015036589A1 (de) * | 2013-09-13 | 2015-03-19 | Johann Wolfgang Goethe-Universität | Küvette für eine inverse fluoreszenz-untersuchung |
JP2015165249A (ja) * | 2015-06-25 | 2015-09-17 | 株式会社Screenホールディングス | 試料保持プレート、撮像装置および撮像方法 |
WO2016009796A1 (ja) * | 2014-07-14 | 2016-01-21 | 株式会社日立ハイテクノロジーズ | マルチチャンネル分析装置 |
JP2017058352A (ja) * | 2015-09-18 | 2017-03-23 | シスメックス株式会社 | 粒子撮像装置および粒子撮像方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11295208A (ja) * | 1998-04-13 | 1999-10-29 | Sysmex Corp | 粒子撮像装置 |
US6522775B2 (en) | 2001-03-28 | 2003-02-18 | Alan C. Nelson | Apparatus and method for imaging small objects in a flow stream using optical tomography |
JP2010256320A (ja) * | 2009-02-09 | 2010-11-11 | Fujifilm Corp | 光波干渉測定装置 |
JP5997256B2 (ja) | 2011-04-15 | 2016-09-28 | コンスティテューション・メディカル・インコーポレイテッドConstitution Medical, Inc. | 細胞の体積および成分の計測 |
JP2015211727A (ja) * | 2014-05-01 | 2015-11-26 | オリンパス株式会社 | 内視鏡装置 |
JP6454489B2 (ja) * | 2014-07-10 | 2019-01-16 | オリンパス株式会社 | 観察システム |
WO2016154038A1 (en) * | 2015-03-20 | 2016-09-29 | Illumina, Inc. | Fluidics cartridge for use in the vertical or substantially vertical position |
-
2018
- 2018-05-28 CN CN201820801491.3U patent/CN208795640U/zh active Active
- 2018-05-28 CN CN201880035531.0A patent/CN110678736B/zh active Active
- 2018-05-28 EP EP18809727.3A patent/EP3633350A4/en not_active Withdrawn
- 2018-05-28 JP JP2019522204A patent/JP7070566B2/ja active Active
- 2018-05-28 WO PCT/JP2018/020257 patent/WO2018221430A1/ja active Application Filing
-
2019
- 2019-11-26 US US16/695,661 patent/US11333596B2/en active Active
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0843400A (ja) * | 1994-07-29 | 1996-02-16 | Olympus Optical Co Ltd | 特異的結合反応を応用した分析方法及び装置並びにこれに用いられる反応容器 |
JPH10253624A (ja) * | 1997-03-13 | 1998-09-25 | Toa Medical Electronics Co Ltd | 粒子測定装置 |
JPH11183358A (ja) * | 1997-12-25 | 1999-07-09 | Kowa Co | 蛍光粒子撮像用容器 |
JP2001133397A (ja) * | 1999-11-05 | 2001-05-18 | Fujirebio Inc | 検体の検査装置 |
JP2009002674A (ja) * | 2007-06-19 | 2009-01-08 | Furukawa Electric Co Ltd:The | 微細粒子のスクリーニング装置および微細粒子のスクリーニング方法 |
WO2010122346A1 (en) * | 2009-04-23 | 2010-10-28 | Avacta Limited | Cuvette and optical method |
EP2450690A1 (en) * | 2010-11-04 | 2012-05-09 | Qiagen GmbH | Vessel for Accurate Optical Measurements |
JP2013170861A (ja) * | 2012-02-20 | 2013-09-02 | Dainippon Screen Mfg Co Ltd | 撮像装置、試料保持プレートおよび撮像方法 |
WO2015036589A1 (de) * | 2013-09-13 | 2015-03-19 | Johann Wolfgang Goethe-Universität | Küvette für eine inverse fluoreszenz-untersuchung |
WO2016009796A1 (ja) * | 2014-07-14 | 2016-01-21 | 株式会社日立ハイテクノロジーズ | マルチチャンネル分析装置 |
JP2015165249A (ja) * | 2015-06-25 | 2015-09-17 | 株式会社Screenホールディングス | 試料保持プレート、撮像装置および撮像方法 |
JP2017058352A (ja) * | 2015-09-18 | 2017-03-23 | シスメックス株式会社 | 粒子撮像装置および粒子撮像方法 |
Non-Patent Citations (2)
Title |
---|
"13.分光光度計用セル・NMR試料管", 総合カタログ30, JPN7018002614, April 2013 (2013-04-01), JP, ISSN: 0004742932 * |
"4.H.ライフサイエンス・分析〜分析機器・用品", 研究用総合機器2017, JPN7018002613, November 2016 (2016-11-01), JP, pages 1241 - 1246, ISSN: 0004742931 * |
Also Published As
Publication number | Publication date |
---|---|
EP3633350A4 (en) | 2020-06-03 |
US11333596B2 (en) | 2022-05-17 |
US20200096435A1 (en) | 2020-03-26 |
EP3633350A1 (en) | 2020-04-08 |
CN208795640U (zh) | 2019-04-26 |
WO2018221430A1 (ja) | 2018-12-06 |
CN110678736A (zh) | 2020-01-10 |
JP7070566B2 (ja) | 2022-05-18 |
CN110678736B (zh) | 2022-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11353439B2 (en) | Method for bone scan in meat | |
KR20170140182A (ko) | 공간적 범위를 갖는 생물학적 샘플의 움직임에 대한 광학적 검출 방법 및 장치 | |
KR102652472B1 (ko) | 혼돈파 센서를 이용한 시료 특성 탐지 장치 | |
WO2016080442A1 (ja) | 品質評価方法及び品質評価装置 | |
KR101872240B1 (ko) | 가시광/근적외선 초분광 현미경기반 영상 측정장치를 이용한 영상 측정방법 | |
CN111366558A (zh) | 一种多波长偏振散射测量装置 | |
CN109477793B (zh) | 质量评估方法以及质量评估装置 | |
JP7070566B2 (ja) | 観察容器及び微小粒子計測装置 | |
WO2018061131A1 (ja) | 細胞状態計測装置 | |
US11768146B2 (en) | Fine particle measurement device | |
JP6895297B2 (ja) | 細胞塊の評価方法及び細胞塊の状態解析装置 | |
CN110050182A (zh) | 用于确定折射率的装置和方法 | |
CN109844606A (zh) | 试样观察装置及试样观察方法 | |
TR202008917A2 (tr) | Çok amaçli spektroskopi̇k, hi̇perspektral ve di̇ji̇tal görüntüleme ci̇hazi | |
US20110310384A1 (en) | Methods and system for confocal light scattering spectroscopic imaging | |
US11624899B2 (en) | Device for analyzing large-area sample based on image, device for analyzing sample based on image by using difference in medium characteristic, and method for measuring and analyzing sample using the same | |
US20230215194A1 (en) | Device for analyzing large-area sample based on image, device for analyzing sample based on image by using difference in medium characteristic, and method for measuring and analyzing sample using the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210322 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220111 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220314 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20220405 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20220418 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7070566 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |