JPWO2018216671A1 - candy - Google Patents

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JPWO2018216671A1
JPWO2018216671A1 JP2019520252A JP2019520252A JPWO2018216671A1 JP WO2018216671 A1 JPWO2018216671 A1 JP WO2018216671A1 JP 2019520252 A JP2019520252 A JP 2019520252A JP 2019520252 A JP2019520252 A JP 2019520252A JP WO2018216671 A1 JPWO2018216671 A1 JP WO2018216671A1
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extract
candy
present
peppermint
green tea
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JP7080880B2 (en
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健太 藤原
健太 藤原
将平 藤原
将平 藤原
雅 山本
雅 山本
美保 山下
美保 山下
孝文 湊
孝文 湊
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Taisho Pharmaceutical Co Ltd
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Taisho Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates

Abstract

本発明は、(i)エチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルからなる群から選ばれる少なくとも1種、並びに(ii)緑茶抽出物、ペパーミント抽出物、エルダーベリー抽出物、セージ、グァバ、及びトゥルシー抽出物からなる群から選ばれる少なくとも1種、を含む飴であって、清涼感の持続性と良好な風味を兼ね備えた飴を提供する。The present invention relates to (i) at least one selected from the group consisting of ethyl-3-p-menthan-3-carboxamide acetate and monomenthyl succinate; and (ii) a green tea extract, a peppermint extract, an elderberry extract, Provided is a candy comprising at least one selected from the group consisting of sage, guava, and Tulsi extract, the candy having both a sustained refreshing sensation and good flavor.

Description

本発明は、飴に関し、これは、食品、医薬部外品、又は医薬品分野において利用されうる。   The present invention relates to candy, which can be used in the food, quasi-drug, or pharmaceutical fields.

飴のカテゴリーに属する製品において、メントールなどで感じる「清涼感」や酸味で感じる「爽快感」など、喉を含めた口腔内に与える官能的要素が重要視されている。
「清涼感」の付与にあたり、ペパーミント精油、ハッカ精油の主要な構成成分であるl−メントールは清涼感を与える物質として知られている。しかし、l−メントールは揮発性が高く清涼感が持続しない点や飲食物に添加した場合苦味を感じる点などの欠点を持っている。
In products belonging to the candy category, emphasis is placed on the sensual elements imparted to the oral cavity, including the throat, such as the "freshness" felt by menthol and the "freshness" felt by sourness.
In imparting a “cool feeling”, l-menthol, which is a main component of essential oils of peppermint essential oil and mint essential oil, is known as a substance that provides a refreshing feeling. However, l-menthol has drawbacks such as high volatility and a lack of refreshing sensation and a bitter taste when added to foods and drinks.

歯磨組成物にメントール、ペパーミント油、ハッカ油などを配合し、清涼感を付与することは広く行われており、これら成分が配合された市販製品は多数存在する。また、清涼感を強化もしくは清涼感を持続させる検討は数多く行われており、メントール類と各種冷感剤とを含有する毛髪及び身体洗浄剤組成物が優れた清涼効果及びその持続性を有すること、メントール類と各種冷感剤とを組み合わせて冷感効果を有する香料組成物が口腔用組成物に配合されることが知られている(特許文献1及び2)。しかし、いずれの技術も清涼感の持続性は十分でなく、口腔用組成物におけるメントールの苦味の抑制も満足できるものではない。   Menthol, peppermint oil, peppermint oil and the like are blended in dentifrice compositions to impart a refreshing sensation, and there are many commercial products containing these components. In addition, many studies have been conducted to enhance the refreshing sensation or to maintain the refreshing sensation, and that the hair and body cleanser composition containing menthol and various cooling sensations has an excellent refreshing effect and its persistence. It is known that a fragrance composition having a cooling sensation effect is combined with an oral composition by combining menthols and various cooling sensation agents (Patent Documents 1 and 2). However, none of these techniques has a sufficient refreshing sensation, and it is not satisfactory in suppressing the bitterness of menthol in an oral composition.

特開2005−8535号公報JP 2005-8535 A 特開2007−2005号公報JP 2007-2005 A

本発明の目的は、清涼感の持続性と良好な風味を兼ね備えた飴を提供することである。   An object of the present invention is to provide a candy having both a refreshing sensation and good flavor.

本発明者らは、上記課題を解決するために鋭意検討した結果、冷涼成分であるエチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルからなる群から選ばれる少なくとも1種に、緑茶抽出物、ペパーミント抽出物、エルダーベリー抽出物、セージ、グァバ、及びトゥルシー抽出物からなる群から選ばれる少なくとも1種を組み合わせることにより、清涼感の持続性と良好な風味を兼ね備えた飴が調製できることを見出した。   The present inventors have conducted intensive studies in order to solve the above-mentioned problems, and as a result, have found that green tea is selected from at least one selected from the group consisting of ethyl-3-p-menthan-3-carboxamide acetate and monomenthyl succinate, which are cooling components. By combining at least one selected from the group consisting of extract, peppermint extract, elderberry extract, sage, guava, and tulsi extract, it is possible to prepare a candy having both a sustained refreshing sensation and a good flavor. Was found.

かかる知見により得られた本発明の態様は次のとおりである。
(1)(i)エチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルからなる群から選ばれる少なくとも1種、並びに
(ii)緑茶抽出物、ペパーミント抽出物、エルダーベリー抽出物、セージ、グァバ、及びトゥルシー抽出物からなる群から選ばれる少なくとも1種
を含む飴。
(2)成分(ii)が緑茶抽出物及びペパーミント抽出物からなる群から選ばれる少なくとも1種である、(1)に記載の飴。
(3)成分(i)がエチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルを含む、(1)又は(2)に記載の飴。
(4)成分(ii)が緑茶抽出物及びペパーミント抽出物を含む、(2)又は(3)に記載の飴。
The aspects of the present invention obtained from such findings are as follows.
(1) (i) at least one selected from the group consisting of ethyl-3-p-menthan-3-carboxamidoacetate and monomenthyl succinate; and (ii) green tea extract, peppermint extract, elderberry extract, sage Candy containing at least one selected from the group consisting of guava, guava, and Tulsi extract.
(2) The candy according to (1), wherein the component (ii) is at least one selected from the group consisting of a green tea extract and a peppermint extract.
(3) The candy according to (1) or (2), wherein the component (i) contains ethyl-3-p-menthan-3-carboxamidoacetate and monomenthyl succinate.
(4) The candy according to (2) or (3), wherein the component (ii) contains a green tea extract and a peppermint extract.

本発明により、清涼感の持続性と良好な風味を兼ね備えた飴を提供することが可能となった。   ADVANTAGE OF THE INVENTION By this invention, it became possible to provide the candy which had the persistence of the refreshing feeling and the favorable flavor.

本発明において、「エチル−3−p−メンタン−3−カルボキサミドアセテート」とは別名WS−5とも呼ばれ、例えば、Penta Manufacturing社等より市販品を購入することができる冷涼感に優れた化合物の一種であり、通常、香料として菓子類や清涼飲料等の添加剤として使用される。
エチル−3−p−メンタン−3−カルボキサミドアセテートの含有量は、本発明の飴全量に対して通常0.00001〜0.1W/W%であるが、本発明の効果の面から、0.0001〜0.1W/W%が好ましく、0.001〜0.1W/W%がより好ましく、異味・異臭を付与しないという点も含めた総合的観点からより好ましい含有量は、0.0001〜0.01W/W%である。0.1W/W%を超える量を添加すると、エチル−3−p−メンタン−3−カルボキサミドアセテートに起因する不快な刺激味により、服用感が著しく低下するため、好ましくない。
In the present invention, “ethyl-3-p-menthan-3-carboxamidoacetate” is also known as WS-5. For example, a compound having excellent cooling sensation that can be purchased from Penta Manufacturing, etc. It is a kind and is usually used as an additive for confectionery and soft drinks as a flavor.
The content of ethyl-3-p-menthan-3-carboxamidoacetate is usually 0.00001 to 0.1 W / W% based on the total amount of the candy of the present invention. The content is preferably from 0001 to 0.1 W / W%, more preferably from 0.001 to 0.1 W / W%, and the content is more preferably 0.0001 to 0.1 W / W% from the comprehensive viewpoint including the point that no off-flavor or odor is imparted. 0.01 W / W%. It is not preferable to add an amount exceeding 0.1 W / W%, because the unpleasant irritating taste caused by ethyl-3-p-menthan-3-carboxamide acetate significantly reduces the feeling of taking.

本発明において、「コハク酸モノメンチル」とは、例えば、東京化成工業等より市販品を購入することができる冷涼感に優れた化合物の一種であり、通常、香料として菓子類や清涼飲料等の添加剤として使用される。
コハク酸モノメンチルの配合量は、本発明の飴全量に対して0.0001〜1W/W%であり、好ましくは0.004〜0.5W/W%であり、より好ましくは0.01〜0.5W/W%である。配合量が0.0001W/W%未満では、清涼感の持続性が十分に得られず、1W/W%を超えるとむしろ清涼感が抑えられ、香味発現が阻害されて使用上好ましくない。
In the present invention, "monomenthyl succinate" is, for example, a kind of a compound having an excellent cooling sensation that can be purchased from Tokyo Chemical Industry or the like, and is usually used as a flavoring agent for confectioneries and refreshing beverages. Used as an agent.
The blending amount of monomenthyl succinate is 0.0001 to 1 W / W%, preferably 0.004 to 0.5 W / W%, more preferably 0.01 to 0 W / W% based on the total amount of the candy of the present invention. 0.5 W / W%. If the amount is less than 0.0001 W / W%, the sustainability of the refreshing feeling cannot be sufficiently obtained, and if it exceeds 1 W / W%, the refreshing feeling is rather suppressed and the expression of flavor is inhibited, which is not preferable in use.

本発明において、「緑茶抽出物」とは、例えばCamellia属(例えばC.sinensis及びC.assamica)の例えばやぶきた種又はそれらの雑種から得られる茶葉から、例えば40〜140℃で0.1分〜120時間加熱処理した緑茶葉抽出液の濃縮物を溶剤抽出あるいは吸着剤等を用いて精製したものを使用できる。市販品として、例えば、商品名「ピュアフェノン」(小川香料(株)製)、商品名「ポリフェノン」(東京フードテクノ(株)製)、商品名「テアフラン」(伊藤園(株)製)、商品名「サンフェノン」(太陽化学(株)製)等を利用してもよい。
緑茶抽出物の配合量は、本発明の飴全量に対して0.0001〜10W/W%であり、好ましくは0.01〜5W/W%である。配合量が10W/W%以上では、苦味が強く発現し、使用上好ましくない。
In the present invention, “green tea extract” refers to, for example, 0.1 minute at 40 to 140 ° C. from tea leaves obtained from, for example, a camellia species of the genus Camellia (eg, C. sinensis and C. assamica) or hybrids thereof. A green tea leaf extract concentrate that has been heat-treated for up to 120 hours may be purified by solvent extraction or an adsorbent. Commercially available products include, for example, “Purephenon” (trade name, manufactured by Kogawa Kogyo Co., Ltd.), “Polyphenon” (trade name, manufactured by Tokyo Food Techno Co., Ltd.), “Theafran” (trade name, manufactured by ITO EN Co., Ltd.) The name “Sanphenon” (manufactured by Taiyo Chemical Co., Ltd.) may be used.
The blending amount of the green tea extract is 0.0001 to 10 W / W%, preferably 0.01 to 5 W / W%, based on the total amount of the candy of the present invention. When the blending amount is 10 W / W% or more, bitterness is strongly exhibited, which is not preferable in use.

本発明において、「ペパーミント抽出物」とは、例えばシソ科属のペパーミント(Mentha pipertia L.別名はセイヨウハッカ)の葉または全草から、水、二酸化炭素若しくはエタノール等の有機溶剤により抽出するか、又は水蒸気蒸留により得られたペパーミント抽出液の濃縮物を溶剤抽出あるいは吸着剤等を用いて精製したものを使用できる。市販品として、例えば、商品名「ペパーミント抽出液BG」(丸善製薬(株))、商品名「ミントポリフェノール」(小川香料(株))等を利用してもよい。
ペパーミント抽出物の配合量は、本発明の飴全量に対して0.0001〜10W/W%であり、好ましくは0.001〜5W/W%であり、より好ましくは0.01〜5W/W%である。配合量が10W/W%以上では、苦味・渋みが強く使用上好ましくない。
In the present invention, "peppermint extract" refers to, for example, extracted from leaves or whole grass of peppermint of the genus Labiatae (Mentha pipetia L. also known as common mint) with an organic solvent such as water, carbon dioxide or ethanol, Alternatively, a concentrate obtained by extracting a peppermint extract obtained by steam distillation using a solvent extraction or an adsorbent can be used. As a commercially available product, for example, trade name “Peppermint Extract BG” (Maruzen Pharmaceutical Co., Ltd.), trade name “Mint Polyphenol” (Ogawa Perfume Co., Ltd.) and the like may be used.
The blending amount of the peppermint extract is 0.0001 to 10 W / W%, preferably 0.001 to 5 W / W%, more preferably 0.01 to 5 W / W, based on the total amount of the candy of the present invention. %. If the compounding amount is 10 W / W% or more, bitterness and astringency are strong, which is not preferable for use.

本発明において、「エルダーベリー抽出物」とは、ニワトコ属の植物であるセイヨウニワトコの果実から抽出・精製されたエキス又は粉末であり、例えば、市販品の「エルダーベリー果実色素」(トレードピア(株))、「エルダーベリーエキス末」((株)ライフヘルスケア)等を利用してもよい。   In the present invention, the “elderberry extract” is an extract or powder extracted and purified from the fruit of the elderberry, which is a plant of the genus Elderberry. For example, a commercially available “Elderberry fruit pigment” (tradepia ( ), "Elderberry Extract Powder" (Life Healthcare Co., Ltd.) and the like.

本発明において、「セージ」とは、シソ科の植物であるセージの葉または花穂を粉砕或いは抽出・精製することにより得られた粉末又はエキスであり、例えば、市販品の「セージパウダー」(エスビー食品(株))、「セージ乾燥エキス」(アスク薬品(株))等を利用してもよい。   In the present invention, the term "sage" refers to a powder or extract obtained by crushing, extracting, or purifying sage leaves or spikes of a Lamiaceae plant. For example, commercially available "sage powder" (S.B. Foods Co., Ltd.), "Sage Dried Extract" (Ask Pharmaceutical Co., Ltd.) and the like may be used.

本発明において、「グァバ」とは、フトモモ科に属する植物グァバの葉を粉砕或いは抽出・精製することにより得られた粉末又はエキスであり、例えば、「グァバフェノン」(備前化成(株))、「グァバの葉(粉末)」((株)ピーアットライフ)等を利用してもよい。   In the present invention, “guava” is a powder or extract obtained by crushing or extracting / purifying leaves of a plant guava belonging to the family Myrtaceae, for example, “Guavaphenone” (Bizen Kasei Co., Ltd.), "Guava leaves (powder)" (Pat Life Co., Ltd.) or the like may be used.

本発明において、「トゥルシー抽出物」とは、シソ科に属する植物トゥルシーの葉を抽出・精製することにより得られたエキス又は粉末であり、例えば「トゥルシー抽出物」、「トゥルシーSCFE」((株)サビンサジャパンコーポレーション)、「ホーリーバジルエキス」(バイオアクティブズジャパン(株))等を利用してもよい。
エルダーベリー抽出物、セージ、グァバ、トゥルシー抽出物の各配合量は、本発明の飴全量に対して0.0001〜10W/W%であり、好ましくは0.001〜5W/W%である。配合量が10W/W%以上では、苦味・渋みが強く使用上好ましくない。
In the present invention, the “Tulsi extract” is an extract or powder obtained by extracting and purifying leaves of a plant Tulsi belonging to the Labiatae family. For example, “Tulsi extract”, “Tulsi SCFE” ((stock) ) Sabinsa Japan Corporation), “Holy Basil Extract” (Bioactives Japan K.K.) and the like may be used.
The amount of each of the elderberry extract, sage, guava, and tulsi extract is 0.0001 to 10 W / W%, preferably 0.001 to 5 W / W%, based on the total amount of the candy of the present invention. If the compounding amount is 10 W / W% or more, bitterness and astringency are strong, which is not preferable for use.

本発明の飴の一実施態様では、緑茶抽出物及びペパーミント抽出物からなる群から選ばれる少なくとも1種を含むことが好ましく、緑茶抽出物及びペパーミント抽出物を含むことが特に好ましい。
本発明の飴の別の実施態様では、エチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルを含むことが好ましい。
本発明の飴の更なる実施態様では、エチル−3−p−メンタン−3−カルボキサミドアセテート、コハク酸モノメンチル、緑茶抽出物を含むことが好ましい。
In one embodiment of the candy of the present invention, it preferably contains at least one member selected from the group consisting of a green tea extract and a peppermint extract, and particularly preferably contains a green tea extract and a peppermint extract.
In another embodiment of the candy of the present invention, it preferably comprises ethyl-3-p-menthan-3-carboxamide acetate and monomenthyl succinate.
In a further embodiment of the candy of the present invention, it preferably comprises ethyl-3-p-menthan-3-carboxamide acetate, monomenthyl succinate, green tea extract.

本発明の「飴」とは、糖、糖アルコール、水あめなどを主原料とする口腔内で溶解および咀嚼して服用する固形物であり、例えば、ハードキャンディ、ソフトキャンディ、トローチ、錠菓、フィルム剤が挙げられるが、これに限定されるものではなく、また、その製造方法、形状および容器等の包装形態も限定されるものではない。また、飴には、上述した成分以外にもその他の成分として、糖類や糖アルコール類(砂糖、ブドウ糖、果糖、異性化糖、還元水あめ、マルチトール、ソルビトール、パラチニット、エリスリトール、オリゴ糖など)、塩類(食塩など)、甘味料(アスパルテーム、アセスルファムカリウム、スクラロース、アドバンテーム、ネオテーム、プシコースなど)、酸味料(クエン酸、リンゴ酸、酒石酸、フマル酸、アスコルビン酸、リン酸など)、香料、着色料、保存料、ミネラル類、ビタミン類、アミノ酸及びその塩類、生薬、生薬抽出物、カフェイン、ローヤルゼリー、食物繊維等を、本発明の効果を損なわない範囲で適宜に配合することができる。   The "candy" of the present invention is a solid substance that is dissolved and chewed in the oral cavity and mainly taken from sugar, sugar alcohol, starch syrup, etc., for example, hard candy, soft candy, troche, tablet confectionery, film Examples thereof include, but are not limited to, agents, and methods for producing the same, shapes, and packaging forms such as containers are not limited. In addition, in addition to the above-mentioned components, candy includes sugars and sugar alcohols (sugar, glucose, fructose, isomerized sugar, reduced starch syrup, maltitol, sorbitol, palatinit, erythritol, oligosaccharides, etc.), Salts (salts, etc.), sweeteners (aspartame, acesulfame potassium, sucralose, advantame, neotame, psicose, etc.), acidulants (citric acid, malic acid, tartaric acid, fumaric acid, ascorbic acid, phosphoric acid, etc.), flavors, coloring Ingredients, preservatives, minerals, vitamins, amino acids and salts thereof, crude drugs, crude drug extracts, caffeine, royal jelly, dietary fiber, and the like can be appropriately blended as long as the effects of the present invention are not impaired.

以下に、実施例、比較例及び試験例を挙げ、本発明を更に詳細に説明するが、これらは、本発明の範囲を何ら限定するものではない。   Hereinafter, the present invention will be described in more detail with reference to Examples, Comparative Examples, and Test Examples, but these do not limit the scope of the present invention at all.

砂糖167gと水あめ167gに水60gを添加し、常法にて加熱溶解して煮詰め、飴生地300gを調製した。その後、表1〜6記載の組成となるように各成分を飴生地に添加し、成形、冷却固化させることでハードキャンディ(1個あたり2.3g、1処方あたり40個)を得た。得られたサンプル1個について試食し、舐め終わってから10分後の清涼感を実施例1〜9および比較例1〜4はパネル4名にて、また、実施例10〜13および比較例5〜10はパネル3名にてVAS(Visual Analog Scale)法を用いて評価した。すなわち、横に引かれた直線の左端を「清涼感を感じない」、右端を「清涼感を非常に感じる」とし、清涼感の程度を左端からの距離を測定して点数とした。各サンプル毎に平均値を算出した上で、各コントロール(実施例1、2については比較例1;実施例3〜5については比較例2;実施例6〜8、10〜13、比較例5〜8については比較例3;実施例9については比較例4;比較例10については比較例9)の清涼感を1とした場合の値を算出した。なお、実施例のペパーミント抽出物は小川香料(株)の「ミントポリフェノール」を、緑茶抽出物は小川香料(株)の「ピュアフェノン」を、エルダーベリー抽出物はトレードピア(株)の「エルダーベリー果実色素」を、セージ粉末はエスビー食品(株)の「セージパウダー」を、グァバ粉末は(株)ピーアットライフの「グァバの葉(粉末)」を、トゥルシー抽出物は(株)サビンサジャパンコーポレーションの「トゥルシーSCFE」を使用した。また、比較例のカシス抽出物は(株)明治フードマテリアの「明治カシスポリフェノール(AC10)」を、はちみつは日新蜂蜜(株)の「純粋ハンガリー産アカシアはちみつ」を、エルダーフラワー抽出物は(株)生活の木の「有機エルダーフラワー」より熱水抽出したものを、プロポリス抽出物は(株)FAPジャパンの「超臨界抽出プロポリスエキス末」を使用した。また、表中の「香料※」には、エチル−3−p−メンタン−3−カルボキサミドアセテート(WS−5)、N,2,3−トリメチル−2−(1−メチルエチル)ブタンアミド(WS−23)およびコハク酸モノメンチルのいずれも含まれていない。   60 g of water was added to 167 g of sugar and 167 g of starch syrup, and the mixture was dissolved by heating in a conventional manner and boiled down to prepare 300 g of candy dough. Thereafter, each component was added to the candy dough so as to have the composition shown in Tables 1 to 6, molded, cooled and solidified to obtain hard candy (2.3 g per piece, 40 pieces per prescription). One sample obtained was tasted, and the refreshing feeling 10 minutes after licking was finished was evaluated by four panelists in Examples 1 to 9 and Comparative Examples 1 to 4, and in Examples 10 to 13 and Comparative Example 5 10 to 10 were evaluated by three panelists using the VAS (Visual Analog Scale) method. That is, the left end of the straight line drawn horizontally was “do not feel a refreshing sensation”, the right end was “feeling a refreshing sensation”, and the degree of the refreshing sensation was measured by measuring the distance from the left end. After calculating the average value for each sample, each control (Comparative Example 1 for Examples 1 and 2; Comparative Example 2 for Examples 3 to 5; Examples 6 to 8, 10 to 13, and Comparative Example 5) The values of Comparative Example 3 for Examples 8 to 9; Comparative Example 4 for Example 9; and Comparative Example 9 for Comparative Example 10 where the cooling sensation was 1 were calculated. In addition, the peppermint extract of the examples is "Mint Polyphenol" of Ogawa Perfume Co., Ltd., the green tea extract is "Pure Phenone" of Ogawa Perfume Co., Ltd., and the elderberry extract is "Elder" of Tradepia Co., Ltd. Berry fruit pigment ”, sage powder is“ Sage Powder ”of SB Foods Co., Ltd., guava powder is“ Guava leaf (powder) ”of P @ at Life Co., Ltd., and Tulsi extract is Sabinsa Japan Co., Ltd. Corporation "Tulsi SCFE" was used. In addition, the cassis extract of Comparative Example was “Meiji Cassis Polyphenol (AC10)” of Meiji Food Materia Co., Ltd., the honey was “Pure Hungarian Acacia Honey” of Nisshin Honey Co., Ltd., and the elder flower extract was ( The hot water extracted from "Organic Elder Flower" of Living Tree Co., Ltd., and the propolis extract used was "Supercritical Extraction Propolis Extract Powder" from FAP Japan. In addition, “perfume *” in the table includes ethyl-3-p-menthan-3-carboxamide acetate (WS-5), N, 2,3-trimethyl-2- (1-methylethyl) butanamide (WS- Neither 23) nor monomenthyl succinate is contained.

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比較例1に対し、実施例1および実施例2の10分後の清涼感が強いことが認められた。
比較例2に対し、実施例3および実施例4の10分後の清涼感が強く、実施例5では、さらに清涼感が強いことが認められた。
比較例3に対し、実施例6、10〜13の10分後の清涼感が強く、実施例7および実施例8はさらに清涼感が強いことが認められた。
比較例4に対し、実施例9の10分後の清涼感が強いことが認められた。
実施例1〜13では、コントロールである比較例1〜4に比べて、舐め終わってから10分後の清涼感の持続性の向上効果が認められた。また、比較例5〜8の素材、比較例10の冷涼成分では、舐め終わってから10分後の清涼感の持続性の向上効果がないことがわかった。
Compared to Comparative Example 1, it was recognized that the refreshing sensation of Example 1 and Example 2 after 10 minutes was stronger.
Compared to Comparative Example 2, it was found that the refreshing sensation after 10 minutes in Examples 3 and 4 was stronger, and that in Example 5, the refreshing sensation was stronger.
Compared to Comparative Example 3, it was found that the refreshing sensation after 10 minutes of Examples 6 and 10 to 13 was stronger, and that the cooling sensations of Examples 7 and 8 were even stronger.
Compared to Comparative Example 4, it was recognized that the refreshing feeling after 10 minutes of Example 9 was stronger.
In Examples 1 to 13, the effect of improving the sustainability of the refreshing feeling 10 minutes after licking was recognized, as compared with Comparative Examples 1 to 4 as the control. In addition, it was found that the materials of Comparative Examples 5 to 8 and the cooling component of Comparative Example 10 had no effect of improving the sustainability of the refreshing feeling 10 minutes after licking was completed.

本発明により、清涼感の持続性と良好な風味を兼ね備えた飴を提供することが可能となった。よって、本発明を医薬品、医薬部外品及び食品として提供することにより、これらの産業の発達が期待される。   ADVANTAGE OF THE INVENTION By this invention, it became possible to provide the candy which had the persistence of the refreshing feeling and the favorable flavor. Therefore, development of these industries is expected by providing the present invention as pharmaceuticals, quasi-drugs, and foods.

本出願は、日本で2017年5月23日に出願された特願2017−101767号を基礎としており、その内容は本明細書にすべて包含される。   This application is based on a patent application No. 2017-101767 filed on May 23, 2017 in Japan, the contents of which are incorporated in full herein.

Claims (4)

(i)エチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルからなる群から選ばれる少なくとも1種、並びに
(ii)緑茶抽出物、ペパーミント抽出物、エルダーベリー抽出物、セージ、グァバ、及びトゥルシー抽出物からなる群から選ばれる少なくとも1種
を含む飴。
(I) at least one selected from the group consisting of ethyl-3-p-menthan-3-carboxamide acetate and monomenthyl succinate; and (ii) green tea extract, peppermint extract, elderberry extract, sage, guava, And a candy comprising at least one selected from the group consisting of Tulsi extract.
成分(ii)が緑茶抽出物及びペパーミント抽出物からなる群から選ばれる少なくとも1種である、請求項1に記載の飴。   The candy according to claim 1, wherein the component (ii) is at least one selected from the group consisting of a green tea extract and a peppermint extract. 成分(i)がエチル−3−p−メンタン−3−カルボキサミドアセテート及びコハク酸モノメンチルを含む、請求項1又は2に記載の飴。   The candy according to claim 1 or 2, wherein component (i) comprises ethyl-3-p-menthan-3-carboxamidoacetate and monomenthyl succinate. 成分(ii)が緑茶抽出物及びペパーミント抽出物を含む、請求項2又は3に記載の飴。   The candy according to claim 2 or 3, wherein component (ii) comprises a green tea extract and a peppermint extract.
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