JPWO2013136943A1 - 血液成分分離装置、及び遠心分離器 - Google Patents
血液成分分離装置、及び遠心分離器 Download PDFInfo
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- JPWO2013136943A1 JPWO2013136943A1 JP2014504755A JP2014504755A JPWO2013136943A1 JP WO2013136943 A1 JPWO2013136943 A1 JP WO2013136943A1 JP 2014504755 A JP2014504755 A JP 2014504755A JP 2014504755 A JP2014504755 A JP 2014504755A JP WO2013136943 A1 JPWO2013136943 A1 JP WO2013136943A1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
- B04B7/08—Rotary bowls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0231—Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16J—PISTONS; CYLINDERS; SEALINGS
- F16J15/00—Sealings
- F16J15/16—Sealings between relatively-moving surfaces
- F16J15/34—Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member
- F16J15/3436—Pressing means
- F16J15/344—Pressing means the pressing force being applied by means of an elastic ring supporting the slip-ring
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16J—PISTONS; CYLINDERS; SEALINGS
- F16J15/00—Sealings
- F16J15/16—Sealings between relatively-moving surfaces
- F16J15/34—Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member
- F16J15/3464—Mounting of the seal
- F16J15/3476—Means for minimising vibrations of the slip-ring
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16J—PISTONS; CYLINDERS; SEALINGS
- F16J15/00—Sealings
- F16J15/16—Sealings between relatively-moving surfaces
- F16J15/34—Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member
- F16J15/36—Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member connected by a diaphragm or bellow to the other member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/331—Optical measuring means used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/42—Reducing noise
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Mechanical Engineering (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
Abstract
Description
62 流入管
63 流出通路
70 ステータ
71 底板
72 肩部流路
73 側壁
74 ボウルヘッド
75 ロータ
76 肩部
77 貯血空間
78 外殻
79 内殻
100 血液成分分離装置
110 遠心槽
112 蓋部
120 シール機構部分
121 リングキャップ
122 樹脂リング
125 固定リング
130 底部流路
621 管内流路
731 支持部
741 首部
742 リブ
743 肩部分
BC バフィーコート
PLT 血小板
PPP 血漿
RBC 赤血球
WBC 白血球
Claims (4)
- 血液または血液成分の流入口及び流出口を備えるステータと、前記ステータに対して回転可能に設けられたロータとを備える遠心分離器を有する血液成分分離装置において、
前記ステータと前記ロータの回転摺動部位を、所定の押圧力で押圧することによりシールすること、
前記所定の押圧力が、500グラム以下であること、
を特徴とする血液成分分離装置。 - 請求項1に記載する血液成分分離装置において、
前記ロータが、環状の固定リングを有すること、
前記ステータが、前記固定リングと接触し摺動する樹脂リングと、前記樹脂リングを保持するリングキャップを有すること、
前記リングキャップは、前記遠心分離器が前記血液成分分離装置にセットされたときに、前記樹脂リングに対して前記所定の押圧力を与えること、
前記リングキャップのゴム硬さが、60以上、かつ66以下であること、
を特徴とする血液成分分離装置。 - 請求項2に記載する血液成分分離装置において、
前記遠心分離器に血液を流入させない状態で前記ロータを回転させたときに、前記固定リングが前記樹脂リングに対して、スティックスリップを抑制すること、
を特徴とする血液成分分離装置。 - 血液または血液成分の流入口及び流出口を備えるステータと、前記ステータに対して回転可能に設けられたロータと、を有し、血液成分分離装置にセットされて使用される遠心分離器において、
前記ロータが、環状の固定リングを有すること、
前記ステータが、前記固定リングと接触し摺動する樹脂リングと、前記樹脂リングを保持するリングキャップを有すること、
前記リングキャップは、前記遠心分離器が前記血液成分分離装置にセットされたときに、前記樹脂リングに対して所定の押圧力を与えること、
前記リングキャップのゴム硬さが、60以上、かつ66以下であることにより、前記所定の押圧力が、500グラム以下とされること、
を特徴とする遠心分離器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012055878 | 2012-03-13 | ||
JP2012055878 | 2012-03-13 | ||
PCT/JP2013/054491 WO2013136943A1 (ja) | 2012-03-13 | 2013-02-22 | 血液成分分離装置、及び遠心分離器 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2013136943A1 true JPWO2013136943A1 (ja) | 2015-08-03 |
JP6034366B2 JP6034366B2 (ja) | 2016-11-30 |
Family
ID=49160861
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014504755A Active JP6034366B2 (ja) | 2012-03-13 | 2013-02-22 | 血液成分分離装置、及び遠心分離器 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20140378292A1 (ja) |
EP (1) | EP2826503B1 (ja) |
JP (1) | JP6034366B2 (ja) |
CN (1) | CN104168930B (ja) |
WO (1) | WO2013136943A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2985151C (en) * | 2015-05-07 | 2023-06-13 | Aenitis Technologies | Multiple blood bag system |
EP3512577A1 (en) | 2016-09-16 | 2019-07-24 | Fenwal, Inc. | Blood separation systems and methods employing centrifugal and spinning membrane separation techniques |
US11311823B2 (en) | 2019-03-05 | 2022-04-26 | Fenwal, Inc. | Collection of mononuclear cells and peripheral blood stem cells |
EP4238596A3 (en) | 2019-05-23 | 2023-12-13 | Fenwal, Inc. | Centrifugal separation and collection of red blood cells or both red blood cells and plasma |
EP4238595A3 (en) | 2019-05-23 | 2023-11-29 | Fenwal, Inc. | Adjustment of target interface location between separated fluid components in a centrifuge |
EP3791904B1 (en) | 2019-09-16 | 2022-02-09 | Fenwal, Inc. | Dynamic adjustment of algorithms for separation and collection of blood components |
US11969536B2 (en) | 2019-12-12 | 2024-04-30 | Fenwal, Inc. | Systems enabling alternative approaches to therapeutic red blood cell exchange and/or therapeutic plasma exchange |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0545187B2 (ja) * | 1985-04-26 | 1993-07-08 | Baxter Int | |
JPH0714496B2 (ja) * | 1988-10-21 | 1995-02-22 | フィルターミスト インターナショナル ピーエルシー | 分離機およびその作動方法 |
JP2001079452A (ja) * | 1999-07-15 | 2001-03-27 | Hitachi Koki Co Ltd | 遠心機 |
JP2006247217A (ja) * | 2005-03-11 | 2006-09-21 | Terumo Corp | 遠心分離器 |
JP4296149B2 (ja) * | 2002-04-26 | 2009-07-15 | 天藤製薬株式会社 | 包装容器 |
JP2010119913A (ja) * | 2008-11-17 | 2010-06-03 | Hitachi Koki Co Ltd | 遠心分離機 |
JP4808219B2 (ja) * | 2005-08-26 | 2011-11-02 | 巴工業株式会社 | デカンタ型遠心分離機 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3565330A (en) * | 1968-07-11 | 1971-02-23 | Cryogenic Technology Inc | Rotary seal and centrifuge incorporating same |
DE69827019T2 (de) * | 1997-05-20 | 2006-02-02 | Zymequest, Inc., Beverly | Gerät und verfahren zur verarbeitung von biologischen zellen |
CN1182882C (zh) * | 1998-12-24 | 2005-01-05 | 生物安全股份有限公司 | 特别用于浓缩造血干细胞的血液分离系统 |
-
2013
- 2013-02-22 WO PCT/JP2013/054491 patent/WO2013136943A1/ja active Application Filing
- 2013-02-22 EP EP13761915.1A patent/EP2826503B1/en active Active
- 2013-02-22 CN CN201380013864.0A patent/CN104168930B/zh active Active
- 2013-02-22 JP JP2014504755A patent/JP6034366B2/ja active Active
-
2014
- 2014-09-09 US US14/481,603 patent/US20140378292A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0545187B2 (ja) * | 1985-04-26 | 1993-07-08 | Baxter Int | |
JPH0714496B2 (ja) * | 1988-10-21 | 1995-02-22 | フィルターミスト インターナショナル ピーエルシー | 分離機およびその作動方法 |
JP2001079452A (ja) * | 1999-07-15 | 2001-03-27 | Hitachi Koki Co Ltd | 遠心機 |
JP4296149B2 (ja) * | 2002-04-26 | 2009-07-15 | 天藤製薬株式会社 | 包装容器 |
JP2006247217A (ja) * | 2005-03-11 | 2006-09-21 | Terumo Corp | 遠心分離器 |
JP4808219B2 (ja) * | 2005-08-26 | 2011-11-02 | 巴工業株式会社 | デカンタ型遠心分離機 |
JP2010119913A (ja) * | 2008-11-17 | 2010-06-03 | Hitachi Koki Co Ltd | 遠心分離機 |
Also Published As
Publication number | Publication date |
---|---|
CN104168930B (zh) | 2016-10-12 |
EP2826503A1 (en) | 2015-01-21 |
US20140378292A1 (en) | 2014-12-25 |
EP2826503A4 (en) | 2015-11-18 |
WO2013136943A1 (ja) | 2013-09-19 |
EP2826503B1 (en) | 2017-05-03 |
CN104168930A (zh) | 2014-11-26 |
JP6034366B2 (ja) | 2016-11-30 |
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