JPS649991A - Benzoxepino(5,4-c)pyridazine compound - Google Patents

Benzoxepino(5,4-c)pyridazine compound

Info

Publication number
JPS649991A
JPS649991A JP16613587A JP16613587A JPS649991A JP S649991 A JPS649991 A JP S649991A JP 16613587 A JP16613587 A JP 16613587A JP 16613587 A JP16613587 A JP 16613587A JP S649991 A JPS649991 A JP S649991A
Authority
JP
Japan
Prior art keywords
formula
alkyl
compound expressed
benzoxepino
expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16613587A
Other languages
Japanese (ja)
Other versions
JP2531687B2 (en
Inventor
Tatsu Nakao
Kenji Morita
Minoru Obata
Minoru Kawakami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP62166135A priority Critical patent/JP2531687B2/en
Publication of JPS649991A publication Critical patent/JPS649991A/en
Application granted granted Critical
Publication of JP2531687B2 publication Critical patent/JP2531687B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound expressed by formula I (R<1> and R<2> are H, halo gen, trifluoromethyl, OH, amine nitro, cyano, 1-4C alkyl, etc.; R<3> is H, 1-8C alkyl, hydroxy -1-4C alkyl, 2-5C alkanoyloxy -1-4C alkyl, pyridyl, aryl, etc.; dotted line is single bond or double bonds). EXAMPLE:2-( 4-Methoxyphenyl )-10-methyl-2,3,4,4a,5,6-hexahydro [1]-benzoxepino [5,4-c]pyridazine-3-one. USE:An antianxiety agent and biophylaxial ability enhancing agent. PREPARATION:A compound expressed by formula II is reacted with a hydrazine derivative expressed by the formula R<3>-NHNH2 or hydrate thereof of acid addition salt thereof to afford a compound expressed by formula III, which then subjected to ring closure reaction to provided the compound expressed by formula I.
JP62166135A 1987-07-01 1987-07-01 Benzoxepino [5,4-c] pyridazine compounds Expired - Lifetime JP2531687B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62166135A JP2531687B2 (en) 1987-07-01 1987-07-01 Benzoxepino [5,4-c] pyridazine compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62166135A JP2531687B2 (en) 1987-07-01 1987-07-01 Benzoxepino [5,4-c] pyridazine compounds

Publications (2)

Publication Number Publication Date
JPS649991A true JPS649991A (en) 1989-01-13
JP2531687B2 JP2531687B2 (en) 1996-09-04

Family

ID=15825684

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62166135A Expired - Lifetime JP2531687B2 (en) 1987-07-01 1987-07-01 Benzoxepino [5,4-c] pyridazine compounds

Country Status (1)

Country Link
JP (1) JP2531687B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045541A (en) * 1987-11-02 1991-09-03 Yoshitomi Pharmaceutical Industries, Ltd. Fused pyridazine compounds and their pharmaceutical use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045541A (en) * 1987-11-02 1991-09-03 Yoshitomi Pharmaceutical Industries, Ltd. Fused pyridazine compounds and their pharmaceutical use

Also Published As

Publication number Publication date
JP2531687B2 (en) 1996-09-04

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