JPS649991A - Benzoxepino(5,4-c)pyridazine compound - Google Patents
Benzoxepino(5,4-c)pyridazine compoundInfo
- Publication number
- JPS649991A JPS649991A JP16613587A JP16613587A JPS649991A JP S649991 A JPS649991 A JP S649991A JP 16613587 A JP16613587 A JP 16613587A JP 16613587 A JP16613587 A JP 16613587A JP S649991 A JPS649991 A JP S649991A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- compound expressed
- benzoxepino
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound expressed by formula I (R<1> and R<2> are H, halo gen, trifluoromethyl, OH, amine nitro, cyano, 1-4C alkyl, etc.; R<3> is H, 1-8C alkyl, hydroxy -1-4C alkyl, 2-5C alkanoyloxy -1-4C alkyl, pyridyl, aryl, etc.; dotted line is single bond or double bonds). EXAMPLE:2-( 4-Methoxyphenyl )-10-methyl-2,3,4,4a,5,6-hexahydro [1]-benzoxepino [5,4-c]pyridazine-3-one. USE:An antianxiety agent and biophylaxial ability enhancing agent. PREPARATION:A compound expressed by formula II is reacted with a hydrazine derivative expressed by the formula R<3>-NHNH2 or hydrate thereof of acid addition salt thereof to afford a compound expressed by formula III, which then subjected to ring closure reaction to provided the compound expressed by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62166135A JP2531687B2 (en) | 1987-07-01 | 1987-07-01 | Benzoxepino [5,4-c] pyridazine compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62166135A JP2531687B2 (en) | 1987-07-01 | 1987-07-01 | Benzoxepino [5,4-c] pyridazine compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS649991A true JPS649991A (en) | 1989-01-13 |
JP2531687B2 JP2531687B2 (en) | 1996-09-04 |
Family
ID=15825684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62166135A Expired - Lifetime JP2531687B2 (en) | 1987-07-01 | 1987-07-01 | Benzoxepino [5,4-c] pyridazine compounds |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2531687B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5045541A (en) * | 1987-11-02 | 1991-09-03 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused pyridazine compounds and their pharmaceutical use |
-
1987
- 1987-07-01 JP JP62166135A patent/JP2531687B2/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5045541A (en) * | 1987-11-02 | 1991-09-03 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused pyridazine compounds and their pharmaceutical use |
Also Published As
Publication number | Publication date |
---|---|
JP2531687B2 (en) | 1996-09-04 |
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