JPS6456616A - Antiulcer agent - Google Patents
Antiulcer agentInfo
- Publication number
- JPS6456616A JPS6456616A JP21267287A JP21267287A JPS6456616A JP S6456616 A JPS6456616 A JP S6456616A JP 21267287 A JP21267287 A JP 21267287A JP 21267287 A JP21267287 A JP 21267287A JP S6456616 A JPS6456616 A JP S6456616A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- compound
- formula
- during storage
- inhibitory action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE:To obtain an antiulcer agent, containing a specific benzimidazole derivative, having excellent stability during storage and inhibitory action on various experimental ulcers and useful as a remedy for gastric or duodenal ulcers. CONSTITUTION:An antiulcer agent containing 2-[2-(3,5-dimethyl)pyridylmethyl sulfinyl]-5-cyclopropylmeth-yloxybenzimidazole, expressed by formula II and obtained by oxidizing a sulfide compound expressed by formula I with an oxidiz ing agent (e.g., m-chloroperbenzoic acid) in the presence of a reaction solvent as an active ingredient. Sufficient stability during storage is provided by using the above-mentioned compound without carrying out conversion of the compound into an alkali salt thereof. The agent has excellent inhibitory action on gastric acid secretion due to inhibition of (H<+>+K<+>) ATPase (adenosine triphosphatase) activity by oral administration thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21267287A JPH0676323B2 (en) | 1987-08-28 | 1987-08-28 | Anti-ulcer agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21267287A JPH0676323B2 (en) | 1987-08-28 | 1987-08-28 | Anti-ulcer agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6456616A true JPS6456616A (en) | 1989-03-03 |
JPH0676323B2 JPH0676323B2 (en) | 1994-09-28 |
Family
ID=16626486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP21267287A Expired - Lifetime JPH0676323B2 (en) | 1987-08-28 | 1987-08-28 | Anti-ulcer agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0676323B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR890100838A (en) * | 1988-12-22 | 1991-03-15 | Haessle Ab | A novel therapeutic active compound and preparation method therefore. |
-
1987
- 1987-08-28 JP JP21267287A patent/JPH0676323B2/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR890100838A (en) * | 1988-12-22 | 1991-03-15 | Haessle Ab | A novel therapeutic active compound and preparation method therefore. |
Also Published As
Publication number | Publication date |
---|---|
JPH0676323B2 (en) | 1994-09-28 |
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