DK196785A - ACID ADDITION SALTS OF A BASIC TIOETER AND PROCEDURE FOR PREPARING THEREOF - Google Patents

ACID ADDITION SALTS OF A BASIC TIOETER AND PROCEDURE FOR PREPARING THEREOF Download PDF

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Publication number
DK196785A
DK196785A DK196785A DK196785A DK196785A DK 196785 A DK196785 A DK 196785A DK 196785 A DK196785 A DK 196785A DK 196785 A DK196785 A DK 196785A DK 196785 A DK196785 A DK 196785A
Authority
DK
Denmark
Prior art keywords
acid addition
tioeter
preparing
procedure
basic
Prior art date
Application number
DK196785A
Other languages
Danish (da)
Other versions
DK196785D0 (en
Inventor
E Kasztreiner
O Fuchs
A Lazar
N Makk
T Lang
L Toldy
B Stefko
T Balogh
T Somogyi
J Engler
J Kosary
J Borvendeg
E Diesler
A Szabo
B Vitolis
P Matyus
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK196785D0 publication Critical patent/DK196785D0/en
Publication of DK196785A publication Critical patent/DK196785A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

med cystearoin eller et syreadditionssalt deraf, eller behandler 5-dimetylaminometyl-2-furfurylalkohol med svovltrioxyd eller et middel egnet til indførelse af svovltrioxyd i nærværelse af et opløsningsmiddel, og derefter fraskiller og omsætter det herved dannede (5-dimetylaminometyl-2-furylmetyl)-hydrogensulfat med formel III med cysteamin eller et syreadditionssalt deraf. Det vundne syreadditionssalt kan isoleres eller basen I kan frigøres fra og renses og eventuelt omdannes til et andet syreadditionssalt.with cystearoin or an acid addition salt thereof, or treating 5-dimethylaminomethyl-2-furfuryl alcohol with sulfur trioxide or an agent suitable for introducing sulfur trioxide in the presence of a solvent, and then separating and reacting the resulting (5-dimethylaminomethyl-2-furyl) hydrogen sulfate of formula III with cysteamine or an acid addition salt thereof. The obtained acid addition salt can be isolated or the base I can be released from and purified and optionally converted to another acid addition salt.

Forbindelsen I og dens syreadditionssalte er mellemprodukter til fremstilling af l-{2-[5-dimetylaminometyl-2-(furylraetyltio)-ætyl]}-amino-l-metylamino-2-nitroætylen med formlenCompound I and its acid addition salts are intermediates for the preparation of 1- {2- [5-dimethylaminomethyl-2- (furylraethylthio) ethyl]} - amino-1-methylamino-2-nitroethylene of the formula

Figure DK196785AD00021

der er et kendt lægemiddel mod mavesår og tolvfingertarms-sår.There is a known drug for peptic ulcer and duodenal ulcer.

DK196785A 1984-05-02 1985-05-02 ACID ADDITION SALTS OF A BASIC TIOETER AND PROCEDURE FOR PREPARING THEREOF DK196785A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU841690A HU198196B (en) 1984-05-02 1984-05-02 Process for production of basic tioether and its salts
HU169084 1984-05-02

Publications (2)

Publication Number Publication Date
DK196785D0 DK196785D0 (en) 1985-05-02
DK196785A true DK196785A (en) 1985-11-03

Family

ID=10955710

Family Applications (1)

Application Number Title Priority Date Filing Date
DK196785A DK196785A (en) 1984-05-02 1985-05-02 ACID ADDITION SALTS OF A BASIC TIOETER AND PROCEDURE FOR PREPARING THEREOF

Country Status (16)

Country Link
KR (1) KR920005828B1 (en)
AR (1) AR240455A1 (en)
AT (1) AT387573B (en)
CA (1) CA1268474A (en)
CS (1) CS259878B2 (en)
DK (1) DK196785A (en)
ES (1) ES8609292A1 (en)
FI (1) FI88501C (en)
GR (1) GR851062B (en)
HU (1) HU198196B (en)
IT (1) IT1200464B (en)
MX (1) MX161373A (en)
NO (1) NO168942C (en)
PT (1) PT80382B (en)
SU (1) SU1375133A3 (en)
YU (1) YU45714B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
CH640846A5 (en) * 1977-07-29 1984-01-31 Allen & Hanburys Ltd Aminoalkylfuran derivative
ES497514A0 (en) * 1980-12-05 1981-10-16 Liade Sa Lab PROCEDURE FOR OBTAINING A HETEROCICLICAL PRIMARY AMINE DERIVATIVE
ES502940A0 (en) * 1981-06-10 1982-11-01 Lafarquim PROCEDURE FOR OBTAINING DERIVATIVES OF FURIL METHYL MERCAPTAN AND ITS SALTS OF PHARMACOLOGICAL INTEREST
ES8206505A1 (en) * 1981-10-21 1982-08-16 Liade Sa Lab Procedure for obtaining a heterociclic derivative of dimethylamine and its physiologically acceptable salts. (Machine-translation by Google Translate, not legally binding)
ES8301226A1 (en) * 1981-11-20 1982-11-16 Especialidades Latinas Medic U Procedure for obtaining N- (2-5-dimethylamine, methyl-2-furanyl-methyl-thio-ethyl-n'-methyl-s-nitro-etano-diamine. (Machine-translation by Google Translate, not legally binding)

Also Published As

Publication number Publication date
YU73385A (en) 1987-12-31
CS259878B2 (en) 1988-11-15
AR240455A1 (en) 1990-04-30
AT387573B (en) 1989-02-10
CA1268474A (en) 1990-05-01
PT80382B (en) 1987-08-19
FI851742A0 (en) 1985-05-02
IT8520558A0 (en) 1985-05-02
HUT37774A (en) 1986-02-28
SU1375133A3 (en) 1988-02-15
FI88501B (en) 1993-02-15
NO851727L (en) 1985-11-04
NO168942C (en) 1992-04-22
MX161373A (en) 1990-09-18
FI88501C (en) 1993-05-25
YU45714B (en) 1992-07-20
GR851062B (en) 1985-11-25
KR920005828B1 (en) 1992-07-20
FI851742L (en) 1985-11-03
KR850008671A (en) 1985-12-21
CS316085A2 (en) 1988-03-15
ES542782A0 (en) 1986-08-16
DK196785D0 (en) 1985-05-02
PT80382A (en) 1985-06-01
NO168942B (en) 1992-01-13
IT1200464B (en) 1989-01-18
ATA129585A (en) 1988-07-15
HU198196B (en) 1989-08-28
ES8609292A1 (en) 1986-08-16

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