JPS6440484A - Benzopyranopyridineacetic acid ester compound - Google Patents

Benzopyranopyridineacetic acid ester compound

Info

Publication number
JPS6440484A
JPS6440484A JP19679887A JP19679887A JPS6440484A JP S6440484 A JPS6440484 A JP S6440484A JP 19679887 A JP19679887 A JP 19679887A JP 19679887 A JP19679887 A JP 19679887A JP S6440484 A JPS6440484 A JP S6440484A
Authority
JP
Japan
Prior art keywords
formula
compound
substituted
group
benzopyranopyridineacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP19679887A
Other languages
Japanese (ja)
Inventor
Takanori Oe
Kazuyuki Kawasaki
Michio Terasawa
Tomonori Imayoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP19679887A priority Critical patent/JPS6440484A/en
Publication of JPS6440484A publication Critical patent/JPS6440484A/en
Pending legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I {R<1> and R<2> are H or lower alkyl; R<3> is (substituted)phenyl, haloalkyl or group of formula -A-R<4> [A is alkylene; R<4> is (substituted)phenyl, hetero-aryl, OH, alkoxy, alkylthio, phenylthio, acyloxy, carboxy, (substituted)benzoyl, group of formula II, etc.]}. EXAMPLE:2-Hydroxyethyl.alpha,2-dimethyl-5H-[ 1 ]benzopyrano[2,3-b]pyridine-7-ace tic acid 2-hydroxyethyl ester. USE:An anti-inflammatory agent, an analgesic and an antipyretic. The side effect of gastric disorder is remarkably mitigated. PREPARATION:The compound of formula III is made to react with the compound of formula R<3>-X [X is reactive atom. or group (e.g. halogen or methanesulfonyloxy)] preferably in the presence of a base (e.g. potassium carbonate) in an inert solvent (e.g. DMF) at 0-100 deg.C for 1-24hr.
JP19679887A 1987-08-06 1987-08-06 Benzopyranopyridineacetic acid ester compound Pending JPS6440484A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP19679887A JPS6440484A (en) 1987-08-06 1987-08-06 Benzopyranopyridineacetic acid ester compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19679887A JPS6440484A (en) 1987-08-06 1987-08-06 Benzopyranopyridineacetic acid ester compound

Publications (1)

Publication Number Publication Date
JPS6440484A true JPS6440484A (en) 1989-02-10

Family

ID=16363825

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19679887A Pending JPS6440484A (en) 1987-08-06 1987-08-06 Benzopyranopyridineacetic acid ester compound

Country Status (1)

Country Link
JP (1) JPS6440484A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607966A (en) * 1994-12-23 1997-03-04 Alcon Laboratories, Inc. Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory prodrugs
US5643943A (en) * 1994-12-23 1997-07-01 Alcon Laboratories, Inc. Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
US5811453A (en) * 1994-12-23 1998-09-22 Alcon Laboratories, Inc. Viscoelastic compositions and methods of use
US5925673A (en) * 1994-12-23 1999-07-20 Alcon Laboratories, Inc. Benzofurans and benzopyrans as cytoprotective agents
WO2023046078A1 (en) * 2021-09-24 2023-03-30 石家庄迪斯凯威医药科技有限公司 Novel pranoprofen derivative, and pharmaceutical composition and use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4993397A (en) * 1973-01-13 1974-09-05
JPS49125365A (en) * 1973-04-03 1974-11-30

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4993397A (en) * 1973-01-13 1974-09-05
JPS49125365A (en) * 1973-04-03 1974-11-30

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607966A (en) * 1994-12-23 1997-03-04 Alcon Laboratories, Inc. Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory prodrugs
US5643943A (en) * 1994-12-23 1997-07-01 Alcon Laboratories, Inc. Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis
US5811453A (en) * 1994-12-23 1998-09-22 Alcon Laboratories, Inc. Viscoelastic compositions and methods of use
US5811438A (en) * 1994-12-23 1998-09-22 Alcon Laboratories, Inc. Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory products
US5925673A (en) * 1994-12-23 1999-07-20 Alcon Laboratories, Inc. Benzofurans and benzopyrans as cytoprotective agents
US6242480B1 (en) 1994-12-23 2001-06-05 Alcon Laboratories, Inc. Ophthalmic viscoelastic compositions
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
US5908849A (en) * 1995-09-12 1999-06-01 Alcon Laboratories, Inc. Anti-oxidant esters of non-steroidal anti-inflammatory agents
US5998465A (en) * 1995-09-12 1999-12-07 Alcon Laboratories, Inc. Esters of non-steroidal anti-flammatory carboxylic acids
WO2023046078A1 (en) * 2021-09-24 2023-03-30 石家庄迪斯凯威医药科技有限公司 Novel pranoprofen derivative, and pharmaceutical composition and use thereof

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