JPS6438099A - Fused protein or dihydrofolate reductase and bradykinin - Google Patents
Fused protein or dihydrofolate reductase and bradykininInfo
- Publication number
- JPS6438099A JPS6438099A JP8540687A JP8540687A JPS6438099A JP S6438099 A JPS6438099 A JP S6438099A JP 8540687 A JP8540687 A JP 8540687A JP 8540687 A JP8540687 A JP 8540687A JP S6438099 A JPS6438099 A JP S6438099A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- pblak1
- dihydrofolate reductase
- column chromatography
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010022394 Threonine synthase Proteins 0.000 title abstract 2
- 102000004419 dihydrofolate reductase Human genes 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 101800004538 Bradykinin Proteins 0.000 title 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 title 1
- 102100035792 Kininogen-1 Human genes 0.000 title 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 title 1
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 238000004440 column chromatography Methods 0.000 abstract 2
- 239000013612 plasmid Substances 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8540687A JPS6438099A (en) | 1987-04-07 | 1987-04-07 | Fused protein or dihydrofolate reductase and bradykinin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8540687A JPS6438099A (en) | 1987-04-07 | 1987-04-07 | Fused protein or dihydrofolate reductase and bradykinin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6438099A true JPS6438099A (en) | 1989-02-08 |
| JPH0354560B2 JPH0354560B2 (enrdf_load_html_response) | 1991-08-20 |
Family
ID=13857912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8540687A Granted JPS6438099A (en) | 1987-04-07 | 1987-04-07 | Fused protein or dihydrofolate reductase and bradykinin |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6438099A (enrdf_load_html_response) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05507209A (ja) * | 1991-02-06 | 1993-10-21 | ジェネティックス・インスティテュート・インコーポレイテッド | チオレドキシンおよびチオレドキシン様分子に対するペプチドおよび蛋白融合 |
-
1987
- 1987-04-07 JP JP8540687A patent/JPS6438099A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05507209A (ja) * | 1991-02-06 | 1993-10-21 | ジェネティックス・インスティテュート・インコーポレイテッド | チオレドキシンおよびチオレドキシン様分子に対するペプチドおよび蛋白融合 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0354560B2 (enrdf_load_html_response) | 1991-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |