JPS643170A - Novel process for producing pyridine derivative - Google Patents

Novel process for producing pyridine derivative

Info

Publication number
JPS643170A
JPS643170A JP15630187A JP15630187A JPS643170A JP S643170 A JPS643170 A JP S643170A JP 15630187 A JP15630187 A JP 15630187A JP 15630187 A JP15630187 A JP 15630187A JP S643170 A JPS643170 A JP S643170A
Authority
JP
Japan
Prior art keywords
grignard reagent
pyridyl
aldehyde
ketone
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15630187A
Other languages
Japanese (ja)
Other versions
JP2583061B2 (en
JPH013170A (en
Inventor
Naomichi Furukawa
Takashi Fujiwara
Naomasa Shibuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Priority to JP62156301A priority Critical patent/JP2583061B2/en
Publication of JPS643170A publication Critical patent/JPS643170A/en
Publication of JPH013170A publication Critical patent/JPH013170A/en
Application granted granted Critical
Publication of JP2583061B2 publication Critical patent/JP2583061B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Abstract

PURPOSE: To obtain a variety of pyridine derivatives by forming a pyridyl Grignard reagent from 2-, 3-, or 4-iodopyridine and a Grignard reagent and allowing the pyridyl Grignard reagent to reach with a ketone, aldehyde or ester.
CONSTITUTION: A pyridyl Grignard reagent is formed from 2-, 3-. or 4- iodopyridine and a Grignard reagent of the formula: RMgX (R is alkyl, alkenyl; X is halogen) and the pyridyl Grignard reagent is allowed to react with a ketone, aldehyde (containing α,β-unsaturated ketone or aldehyde) or ester to effect the addition of the pyridyl group to the ketone or aldehyde group or conjugated double bonds to give a pyridine derivative such as phenyl-2-pyridylcarbinol, the compound of formula I or formula II.
COPYRIGHT: (C)1989,JPO&Japio
JP62156301A 1987-06-23 1987-06-23 Novel production method of pyridine derivatives Expired - Lifetime JP2583061B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62156301A JP2583061B2 (en) 1987-06-23 1987-06-23 Novel production method of pyridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62156301A JP2583061B2 (en) 1987-06-23 1987-06-23 Novel production method of pyridine derivatives

Publications (3)

Publication Number Publication Date
JPS643170A true JPS643170A (en) 1989-01-06
JPH013170A JPH013170A (en) 1989-01-06
JP2583061B2 JP2583061B2 (en) 1997-02-19

Family

ID=15624818

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62156301A Expired - Lifetime JP2583061B2 (en) 1987-06-23 1987-06-23 Novel production method of pyridine derivatives

Country Status (1)

Country Link
JP (1) JP2583061B2 (en)

Also Published As

Publication number Publication date
JP2583061B2 (en) 1997-02-19

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