JPS6384553A - Plastic container for infusion - Google Patents
Plastic container for infusionInfo
- Publication number
- JPS6384553A JPS6384553A JP61230911A JP23091186A JPS6384553A JP S6384553 A JPS6384553 A JP S6384553A JP 61230911 A JP61230911 A JP 61230911A JP 23091186 A JP23091186 A JP 23091186A JP S6384553 A JPS6384553 A JP S6384553A
- Authority
- JP
- Japan
- Prior art keywords
- ethylene
- propylene
- infusion
- plastic container
- infusions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001802 infusion Methods 0.000 title claims description 17
- 229920003023 plastic Polymers 0.000 title claims description 12
- 239000004033 plastic Substances 0.000 title claims description 12
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 7
- 239000005977 Ethylene Substances 0.000 claims description 7
- 229920005674 ethylene-propylene random copolymer Polymers 0.000 claims description 6
- 238000000071 blow moulding Methods 0.000 claims description 5
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims description 5
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims description 5
- 229920001384 propylene homopolymer Polymers 0.000 claims description 5
- 239000004711 α-olefin Substances 0.000 claims description 2
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000010410 layer Substances 0.000 description 24
- 229920001577 copolymer Polymers 0.000 description 8
- 239000011521 glass Substances 0.000 description 3
- 150000001336 alkenes Chemical class 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003633 blood substitute Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001519 homopolymer Polymers 0.000 description 2
- 239000011229 interlayer Substances 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 2
- 239000003058 plasma substitute Substances 0.000 description 2
- BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229920002457 flexible plastic Polymers 0.000 description 1
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 description 1
- 239000003978 infusion fluid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 229920005604 random copolymer Polymers 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Abstract] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
産業上の利用分野
本発明は、血液・血漿代用液など静脈注射用の輸液を収
容する可撓性を有する輸液用プラスチック容器に関する
ものである。DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to a flexible plastic container for infusion containing intravenous infusions such as blood and plasma substitutes.
従来技術
上記静脈注射用の輸液を収容する容器として従来より多
用されているのはガラス製容器である。BACKGROUND OF THE INVENTION Glass containers have traditionally been widely used as containers for containing the above-mentioned intravenous infusion solutions.
ガラス製容器は、滅菌時に加えられる高温麿に対して十
分に耐えることができ、ざらにきわめて透明性が高いと
いう特徴のほかに、化学的に安定しているので内部から
異物が析出することなくきわめて衛生的であるという特
徴を右する。Glass containers can withstand the high temperatures added during sterilization, are extremely transparent, and are chemically stable, so no foreign substances will precipitate from inside. It has the characteristic of being extremely hygienic.
また、近年溝としてもυ１れないこと、軽量であること
などの利点により急速にプラスチック化が進んでおり、
特に耐熱性・透明性の点よりブ［ｌピレン単独重合体を
ブロー成形した輸液用プラスチック容器が知られている
。In addition, in recent years, the use of plastic has rapidly progressed due to its advantages such as not being able to be used as a groove and being lightweight.
In particular, from the viewpoints of heat resistance and transparency, plastic containers for infusions are known that are made of blow-molded pyrene homopolymer.
発明が解決しようとする問題点
しかしながら、前掲前者のガラス製容器であれば落とす
と割れるという欠点及び重いという欠点を有しており、
さらに前掲後者のプラスチック製容器であれば、硬くて
変形せず、点滴時に口部を下にして、内部に空気を供給
せずども自らの胴部を変形して点滴を行うという所謂「
自然滴下」を行うことができないという欠点を右してい
る。なお、特開昭６１−１３５６６４号公報にプロビレ
ン単独重合体層の両側にエチレン−プロピレン共重合体
層を積層した３層フィルムを２枚重ねてピー１〜シール
して袋状の容器を製造する技術が示されているが、これ
は、フィルムによる成形である点、エチレンンープロピ
レン共重合体が内層と外層に配される点、したがって内
層にエチレン−プロピレン共重合体を配したためにこの
構成でブロー成形したときにエヂレンープロピレン共重
合体同志のピンチオフ強度の低下による底割れが発生し
たり、あるいはエチレン−プロピレン共重合体より析出
する異物が発生ずる点について何ら考慮されておらず、
さらに、外層にエチレン−プロピレン共重合体を配した
ために外からの接触に対して表面が傷付き易く、外観特
に運搬時及び使用時の透明性の低下について考慮されて
いない。Problems to be Solved by the Invention However, the above-mentioned glass containers have the drawbacks of breaking when dropped and being heavy.
Furthermore, if it is a plastic container of the latter type mentioned above, it is hard and does not deform, and during infusion, the mouth part is turned downward and the infusion is carried out by deforming its own body without supplying air inside.
It has the disadvantage of not being able to perform 'natural dripping'. Furthermore, as disclosed in JP-A-61-135664, a bag-shaped container is manufactured by stacking two three-layer films in which ethylene-propylene copolymer layers are laminated on both sides of a propylene homopolymer layer and sealing them. This technology is shown in the following, but this is due to the fact that it is molded by a film and that the ethylene-propylene copolymer is placed in the inner and outer layers. No consideration was given to the occurrence of bottom cracks due to a decrease in the pinch-off strength of the ethylene-propylene copolymer during blow molding, or the occurrence of foreign substances precipitated from the ethylene-propylene copolymer.
Furthermore, since the ethylene-propylene copolymer is disposed in the outer layer, the surface is easily damaged by contact from the outside, and no consideration has been given to reducing the appearance, especially the transparency during transportation and use.
問題点を解決するための手段
本発明は、ブロー成形により形成された内部に血液・血
漿代用液などの輸液を充填する輸液用プラスデック容器
において、プロピレン単独重合体あるいは３重量％未渦
のエチレンもしくはα−オレフィンを含有するプ［ｌピ
レンとの共重合体を内層と外層に配し、その中間層側に
３〜９巾量重量エチレンを含有するエヂレンープロピレ
ンランダム共千合体を配したことを特徴とするものであ
る。Means for Solving the Problems The present invention provides a PlusDeck container for infusions, which is formed by blow molding and is filled with infusions such as blood and plasma substitutes, using propylene homopolymer or 3% by weight non-vortexed ethylene. Alternatively, a copolymer with propylene containing α-olefin is arranged in the inner and outer layers, and an ethylene-propylene random copolymer containing 3 to 9 width weight ethylene is arranged in the middle layer side. It is characterized by this.
作用
このように、プ［］ピビレの単独重合体で構成された輸
液用プラスチック容器の中間層に３〜９申♀％のエチレ
ンを含有するエチレン−プロピレンランダム共重合体を
配したことにより充分なピンチオフ強度と衛生性を保持
するとともに、エチレン−プロピレン共重合体の柔軟性
のために自然滴下が可能であり、エヂレンープロピレン
ランダム共（０合体とプロピレン単独重合体およびエチ
レンｂｂ＜はα−オレフィンとプロピレンとの共重合体
との良好なる層間接着性を有するものである。Effect: As described above, by placing an ethylene-propylene random copolymer containing 3 to 9% ethylene in the middle layer of a plastic container for infusions made of a homopolymer of propylene, sufficient In addition to maintaining pinch-off strength and hygiene, natural dripping is possible due to the flexibility of the ethylene-propylene copolymer. It has good interlayer adhesion with the copolymer of olefin and propylene.
実施例 本発明の一実施例を図面に基づき説明する。Example An embodiment of the present invention will be described based on the drawings.
図中１は、容器本体２及びキレツブ３より構成される輸
液用プラスチック容器である。容器本体２は中間層２ｂ
、外層２ａ及び内層２Ｃより構成され、中間層２ｂには
エチレン−プロピレンランダム共重合体を有し、外層２
ａと内層２ｃにはプロピレン単独重合体を有する。なお
、外層２ａは０．４ＩｒｕｒＩ、中間層２ｂは０．６Ｍ
、内層２ｃは０゜２ｍである。上記輸液用プラスチック
容器１は、上記構成のパリスンをブロー成形することに
より得られる。In the figure, reference numeral 1 indicates a plastic container for infusion, which is composed of a container body 2 and a receptacle 3. The container body 2 has an intermediate layer 2b
, is composed of an outer layer 2a and an inner layer 2C, the middle layer 2b has an ethylene-propylene random copolymer, and the outer layer 2
a and the inner layer 2c contain a propylene homopolymer. In addition, the outer layer 2a is 0.4IrurI, and the middle layer 2b is 0.6M.
, the inner layer 2c is 0°2m. The above-mentioned plastic container 1 for infusion is obtained by blow molding the parison having the above-mentioned structure.
外層２ａ及び内層２Ｃには、プロピレンの単独重合体の
ほか、プロピレンと３重量％未渦のエチレンまたはα−
オレフィンとのランダムもしくはブロック共重合体でも
よい。これらの樹脂はメルトフローレイト（ＪＩＳ
Ｋ６７５８、以下ＭＦＲという）が０．２〜５．０ｇ／
１０ｍ１ｎ、で、曲げ弾性率（ＪＩＳ Ｋ７２０３）
が８０００〜１４０００に！Ｆ／ｃｍのものが使用でき
る。In addition to a propylene homopolymer, the outer layer 2a and the inner layer 2C contain propylene and 3% by weight of unvortexed ethylene or α-
It may also be a random or block copolymer with an olefin. These resins have a melt flow rate (JIS
K6758 (hereinafter referred to as MFR) is 0.2 to 5.0 g/
10m1n, flexural modulus (JIS K7203)
has increased from 8,000 to 14,000! F/cm can be used.
また、中間層２ｂのエチレン−プロピレンランダム共重
合体とは、エチレン含量が３〜９＠量％で、ＭＦＲが０
．５〜３．０ｇ／１０ｍ１ｎ、、曲げ弾性率２０００〜
５０００Ｋｇ／ｃＩｉのものが使用できる。In addition, the ethylene-propylene random copolymer of the intermediate layer 2b has an ethylene content of 3 to 9% by weight and an MFR of 0.
．． 5~3.0g/10m1n, flexural modulus 2000~
5000Kg/cIi can be used.
本発明の目的でめる自然滴下を行いうるための柔軟性を
満足するためには、一般的に６０００Ｋｇ／７以下の曲
げ弾性率であることが必要である。In order to satisfy the flexibility required to perform natural dripping for the purpose of the present invention, it is generally necessary to have a flexural modulus of 6000 kg/7 or less.
このためには、中間層のエヂレンープロピレンランダム
共重合体は、すくなくとも全肉厚に対して５０％以上の
比率の肉厚が必要である。For this purpose, the thickness of the ethylene-propylene random copolymer of the intermediate layer must be at least 50% or more of the total thickness.
発明の効果
本発明は以上のように構成したので、ブロー成形により
形成された容器は、充分なピンチオフ強度と衛生性を保
持しながら、自然滴下を行うに適した柔軟性と層間接着
性を有するものである。Effects of the Invention Since the present invention is configured as described above, the container formed by blow molding has flexibility and interlayer adhesion suitable for natural dripping while maintaining sufficient pinch-off strength and hygiene. It is something.
第１図は本発明の一実施例に係る輸液用プラスチック容
器の仝休を示す斜視図、第２図は第１図の輸液用プラス
チック容器の胴部の一部を示す要部破断側面図である。
１・・・・輸液用プラスチック容器
２・・・・容器本体 ２ａ・・外層
２ｂ・・中間層 ２Ｃ・・内層FIG. 1 is a perspective view showing the rest of the plastic container for infusion according to an embodiment of the present invention, and FIG. 2 is a side view with a main part cut away showing a part of the body of the plastic container for infusion shown in FIG. 1. be. 1...Plastic container for infusion 2...Container body 2a...Outer layer 2b...Middle layer 2C...Inner layer
Claims (1)
液を充填する輸液用プラスチック容器において、内層及
び外層にプロピレン単独重合体あるいは３重量％未満の
エチレンもしくはα−オレフィンを含有するプロピレン
との共重合体を配し、中間層に３〜９重量％のエチレン
を含有するエチレン−プロピレンランダム共重合体を配
して三層構造としたことを特徴とする輸液用プラスチッ
ク容器。In plastic containers for infusions formed by blow molding and filled with infusions for intravenous injection, the inner and outer layers are made of propylene homopolymer or copolymerized with propylene containing less than 3% by weight of ethylene or α-olefin. 1. A plastic container for infusions, characterized in that it has a three-layer structure in which an ethylene-propylene random copolymer containing 3 to 9% by weight of ethylene is arranged in the intermediate layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61230911A JPS6384553A (en) | 1986-09-29 | 1986-09-29 | Plastic container for infusion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61230911A JPS6384553A (en) | 1986-09-29 | 1986-09-29 | Plastic container for infusion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6384553A true JPS6384553A (en) | 1988-04-15 |
| JPH053311B2 JPH053311B2 (en) | 1993-01-14 |
Family
ID=16915214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61230911A Granted JPS6384553A (en) | 1986-09-29 | 1986-09-29 | Plastic container for infusion |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6384553A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62106765A (en) * | 1985-11-01 | 1987-05-18 | 昭和電工株式会社 | Medical bag |
-
1986
- 1986-09-29 JP JP61230911A patent/JPS6384553A/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62106765A (en) * | 1985-11-01 | 1987-05-18 | 昭和電工株式会社 | Medical bag |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH053311B2 (en) | 1993-01-14 |
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