JPS634807B2 - - Google Patents
Info
- Publication number
- JPS634807B2 JPS634807B2 JP406481A JP406481A JPS634807B2 JP S634807 B2 JPS634807 B2 JP S634807B2 JP 406481 A JP406481 A JP 406481A JP 406481 A JP406481 A JP 406481A JP S634807 B2 JPS634807 B2 JP S634807B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- uric acid
- present
- hyperuricemia
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 201000001431 Hyperuricemia Diseases 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- MLCGWPUVZKTVLO-UHFFFAOYSA-N traxanox Chemical compound C=1C(C(C2=CC=CN=C2O2)=O)=C2C(Cl)=CC=1C=1N=NNN=1 MLCGWPUVZKTVLO-UHFFFAOYSA-N 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 description 14
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 12
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 12
- 229940116269 uric acid Drugs 0.000 description 12
- 230000000694 effects Effects 0.000 description 6
- 230000029142 excretion Effects 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 230000002485 urinary effect Effects 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- 238000004737 colorimetric analysis Methods 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000000043 antiallergic agent Substances 0.000 description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- -1 9-chloro-5-oxo-7-(1H -tetrazol-5-yl)-5H-[1]Benzopyrano[2,3-b]pyridine sodium salt Chemical compound 0.000 description 1
- 229940126062 Compound A Drugs 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- CHRHZFQUDFAQEQ-UHFFFAOYSA-L calcium;2-hydroxyacetate Chemical compound [Ca+2].OCC([O-])=O.OCC([O-])=O CHRHZFQUDFAQEQ-UHFFFAOYSA-L 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000012050 conventional carrier Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 150000004686 pentahydrates Chemical class 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- HQAITFAUVZBHNB-UHFFFAOYSA-N sodium;pentahydrate Chemical compound O.O.O.O.O.[Na] HQAITFAUVZBHNB-UHFFFAOYSA-N 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP406481A JPS57118515A (en) | 1981-01-13 | 1981-01-13 | Remedy for hyperuremia |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP406481A JPS57118515A (en) | 1981-01-13 | 1981-01-13 | Remedy for hyperuremia |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57118515A JPS57118515A (en) | 1982-07-23 |
JPS634807B2 true JPS634807B2 (sl) | 1988-02-01 |
Family
ID=11574403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP406481A Granted JPS57118515A (en) | 1981-01-13 | 1981-01-13 | Remedy for hyperuremia |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57118515A (sl) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984001711A1 (en) * | 1982-10-30 | 1984-05-10 | Yoshitomi Pharmaceutical | Hypotensives |
-
1981
- 1981-01-13 JP JP406481A patent/JPS57118515A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS57118515A (en) | 1982-07-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPH11139971A (ja) | ロキソプロフェン含有医薬製剤 | |
US20120142737A1 (en) | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination | |
HUT72313A (en) | Pharmaceutical compositions for treating menstrual symptoms and process for their preparation | |
JP2019533660A (ja) | 急性腎障害を処置する方法 | |
EP0399051B1 (en) | Polyvalent antiinflammatory agent | |
JP2000515559A (ja) | 体重減量方法 | |
JPH0140009B2 (sl) | ||
US3705946A (en) | Method of treating hyperuricemia | |
KR0133555B1 (ko) | 5-플루오로우라실계 화합물에 기인한 염증의 발생을 억제할 수 있는 비-주사제 형태의 항암조성물 | |
JP2009073851A (ja) | ロキソプロフェン含有医薬製剤2 | |
JP3982889B2 (ja) | イブプロフェン含有医薬製剤 | |
CA1273875A (en) | Antiinflammatory compositions and methods | |
JPS634807B2 (sl) | ||
US10045984B2 (en) | Combination therapy | |
EP1353624B1 (en) | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination | |
HU199290B (en) | Process for production of medical compositions against hyperurichemie containing derivatives of oxoquinasoline | |
JP3272369B2 (ja) | イミダゾール誘導体を含有する抗hiv組成物 | |
JP2548223B2 (ja) | 腎臓疾患治療剤 | |
JP2772717B2 (ja) | 高尿酸血症および痛風治療用の薬剤としてのアモルファス状または結晶状のオキシプリノールのアルカリ塩およびアルカリ土類塩 | |
JPS634806B2 (sl) | ||
KR0132568B1 (ko) | 이뇨 또는 항고혈압 조성물 | |
EP0267442B1 (en) | Tetrazolylquinazolinones as anti-hyperuricemic agents | |
EP0301466B1 (en) | Uricosuric composition | |
JP3254712B2 (ja) | 医薬組成物 | |
JP2621382B2 (ja) | 尿酸排泄剤 |