JPS633861B2 - - Google Patents

Info

Publication number
JPS633861B2
JPS633861B2 JP53149382A JP14938278A JPS633861B2 JP S633861 B2 JPS633861 B2 JP S633861B2 JP 53149382 A JP53149382 A JP 53149382A JP 14938278 A JP14938278 A JP 14938278A JP S633861 B2 JPS633861 B2 JP S633861B2
Authority
JP
Japan
Prior art keywords
coumarin
hexyloxy
azide
tetrazol
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53149382A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5576873A (en
Inventor
Kyoshi Kuryama
Jun Nakano
Kyonoshin Ichikawa
Kyoshi Ito
Juji Suzuki
Katsuro Ishizuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP14938278A priority Critical patent/JPS5576873A/ja
Priority to US06/094,502 priority patent/US4363812A/en
Priority to CA000339932A priority patent/CA1144553A/en
Priority to EP79104687A priority patent/EP0011839B1/en
Priority to DE7979104687T priority patent/DE2964859D1/de
Publication of JPS5576873A publication Critical patent/JPS5576873A/ja
Publication of JPS633861B2 publication Critical patent/JPS633861B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP14938278A 1978-11-30 1978-11-30 Coumarin derivative, its preparation, and antiallergic drugs containing it as active constituent Granted JPS5576873A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP14938278A JPS5576873A (en) 1978-11-30 1978-11-30 Coumarin derivative, its preparation, and antiallergic drugs containing it as active constituent
US06/094,502 US4363812A (en) 1978-11-30 1979-11-15 3-(Tetrazol-5-yl), 4-methyl-8-alkoxy coumarins and anti-allergic compositions thereof
CA000339932A CA1144553A (en) 1978-11-30 1979-11-15 Coumarin derivatives, process for preparing the same and composition containing the same
EP79104687A EP0011839B1 (en) 1978-11-30 1979-11-26 Coumarin derivatives, process for preparing the same and pharmaceutical composition containing the same
DE7979104687T DE2964859D1 (en) 1978-11-30 1979-11-26 Coumarin derivatives, process for preparing the same and pharmaceutical composition containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14938278A JPS5576873A (en) 1978-11-30 1978-11-30 Coumarin derivative, its preparation, and antiallergic drugs containing it as active constituent

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP19320283A Division JPS59112985A (ja) 1983-10-15 1983-10-15 クマリン誘導体、その製造法およびそれを有効成分とする抗アレルギ−剤
JP27117184A Division JPS60190715A (ja) 1984-12-21 1984-12-21 クマリン誘導体を有効成分とする抗アレルギ−剤

Publications (2)

Publication Number Publication Date
JPS5576873A JPS5576873A (en) 1980-06-10
JPS633861B2 true JPS633861B2 (en, 2012) 1988-01-26

Family

ID=15473899

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14938278A Granted JPS5576873A (en) 1978-11-30 1978-11-30 Coumarin derivative, its preparation, and antiallergic drugs containing it as active constituent

Country Status (5)

Country Link
US (1) US4363812A (en, 2012)
EP (1) EP0011839B1 (en, 2012)
JP (1) JPS5576873A (en, 2012)
CA (1) CA1144553A (en, 2012)
DE (1) DE2964859D1 (en, 2012)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671087A (en) * 1979-11-15 1981-06-13 Kaken Pharmaceut Co Ltd Courmarine derivative, its preparation, and antiallergic agent containing the same as the effective component
DE2950291A1 (de) * 1979-12-14 1981-06-19 Basf Ag, 6700 Ludwigshafen Neue cumarinverbindungen und verfahren zur herstellung von cumarinverbindungen
JPS56158781A (en) * 1980-05-10 1981-12-07 Kaken Pharmaceut Co Ltd Tetrazolecoumarin derivative, its preparation and antiallergic agent containing the same as active constitutent
JPS61137881A (ja) * 1984-12-10 1986-06-25 Kaken Pharmaceut Co Ltd クロメン誘導体、その製法およびそれを有効成分とする抗アレルギ−剤
US20060257337A1 (en) * 2005-04-28 2006-11-16 David Sherris Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis
USRE46558E1 (en) 2005-04-28 2017-09-26 Paloma Pharmaceuticals, Inc. Compositions and methods to treat diseases characterized by cellular proliferation and angiogenesis
EP1996021B1 (en) * 2006-02-28 2017-12-13 Paloma Pharmaceuticals, Inc. Compositions and methods to treat diseases characterized by cellular proliferation and angiogenesis
EP2271334B1 (en) * 2008-03-25 2015-08-12 Paloma Pharmaceuticals, Inc. Methods of treating fibrotic disorders
WO2012112791A1 (en) 2011-02-16 2012-08-23 Paloma Pharmaceuticals, Inc. Radiation countermeasure agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683720A (en) * 1949-12-15 1954-07-13 Endo Products Inc Process for the preparation of 6-nitro-coumarin-3-carboxylic acid
US2977372A (en) * 1958-04-09 1961-03-28 William G Finnegan Process for preparing substituted tetrazoles
DE1768364A1 (de) * 1968-05-06 1972-08-03 Bayer Ag 7-Cyan-cumarine
BE759292A (fr) * 1969-11-27 1971-05-24 Allen & Hanburys Ltd Derives de xanthone, leur preparation et leur emploi
GB1434645A (en) * 1973-10-11 1976-05-05 Beecham Group Ltd Tetrazole coumarin derivatives
US4059704A (en) * 1973-10-11 1977-11-22 Beecham Group Limited Tetrazole coumarin derivatives
US4116971A (en) * 1977-08-15 1978-09-26 Warner-Lambert Company 3-(1h-tetrazol-5-yl)chromones

Also Published As

Publication number Publication date
EP0011839A1 (en) 1980-06-11
CA1144553A (en) 1983-04-12
JPS5576873A (en) 1980-06-10
DE2964859D1 (en) 1983-03-24
EP0011839B1 (en) 1983-02-16
US4363812A (en) 1982-12-14

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