JPS6313969B2 - - Google Patents

Info

Publication number
JPS6313969B2
JPS6313969B2 JP52029814A JP2981477A JPS6313969B2 JP S6313969 B2 JPS6313969 B2 JP S6313969B2 JP 52029814 A JP52029814 A JP 52029814A JP 2981477 A JP2981477 A JP 2981477A JP S6313969 B2 JPS6313969 B2 JP S6313969B2
Authority
JP
Japan
Prior art keywords
rotor
plasma
gradient
hbs antigen
sodium bromide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52029814A
Other languages
English (en)
Japanese (ja)
Other versions
JPS53115812A (en
Inventor
Jee Makuaree Uiriamu
Etsuchi Wasumusu Edowaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS53115812A publication Critical patent/JPS53115812A/ja
Publication of JPS6313969B2 publication Critical patent/JPS6313969B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Centrifugal Separators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2981477A 1977-02-23 1977-03-19 Hepatisis b antigen Granted JPS53115812A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7657/77A GB1554811A (en) 1977-02-23 1977-02-23 Purifying hepatitis b surface antigen

Publications (2)

Publication Number Publication Date
JPS53115812A JPS53115812A (en) 1978-10-09
JPS6313969B2 true JPS6313969B2 (enrdf_load_stackoverflow) 1988-03-29

Family

ID=9837320

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2981477A Granted JPS53115812A (en) 1977-02-23 1977-03-19 Hepatisis b antigen
JP58010648A Pending JPS58180431A (ja) 1977-02-23 1983-01-27 肝炎ｂ抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP58010648A Pending JPS58180431A (ja) 1977-02-23 1983-01-27 肝炎ｂ抗原

Country Status (6)

Country Link
JP (2) JPS53115812A (enrdf_load_stackoverflow)
CA (1) CA1088426A (enrdf_load_stackoverflow)
CH (1) CH636269A5 (enrdf_load_stackoverflow)
DE (1) DE2709581A1 (enrdf_load_stackoverflow)
FR (1) FR2382238A1 (enrdf_load_stackoverflow)
GB (1) GB1554811A (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7711378A (nl) * 1976-11-02 1978-05-05 Merck & Co Inc Werkwijze voor het bereiden van preparaten die dane-deeltjes bevatten.
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
US4029764A (en) * 1974-12-09 1977-06-14 Merck & Co., Inc. Hepatitis A antigen
US4017360A (en) * 1975-05-14 1977-04-12 Merck & Co., Inc. Method for purifying hepatitis B antigen

Also Published As

Publication number Publication date
JPS58180431A (ja) 1983-10-21
JPS53115812A (en) 1978-10-09
CH636269A5 (en) 1983-05-31
DE2709581A1 (de) 1978-09-07
GB1554811A (en) 1979-10-31
DE2709581C2 (enrdf_load_stackoverflow) 1988-04-07
FR2382238A1 (fr) 1978-09-29
CA1088426A (en) 1980-10-28
FR2382238B1 (enrdf_load_stackoverflow) 1981-05-29

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