JPS631305B2 - - Google Patents

Info

Publication number
JPS631305B2
JPS631305B2 JP53153804A JP15380478A JPS631305B2 JP S631305 B2 JPS631305 B2 JP S631305B2 JP 53153804 A JP53153804 A JP 53153804A JP 15380478 A JP15380478 A JP 15380478A JP S631305 B2 JPS631305 B2 JP S631305B2
Authority
JP
Japan
Prior art keywords
group
formula
carbon atoms
trifluoromethyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53153804A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5488277A (en
Inventor
Are Andore
Meie Jan
Dorae Roje
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7737835A external-priority patent/FR2411832A1/fr
Priority claimed from FR7737836A external-priority patent/FR2411833A1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS5488277A publication Critical patent/JPS5488277A/ja
Publication of JPS631305B2 publication Critical patent/JPS631305B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP15380478A 1977-12-15 1978-12-14 Novel derivative of 22**44quinolinyl* amino** 55fluorobenzoic acid*its manufacture and pharmaceutical composition containing it Granted JPS5488277A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7737835A FR2411832A1 (fr) 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2/(4-quinoleinyl) amino/5-fluorobenzoique, leur procede de preparation et leur application comme medicament.
FR7737836A FR2411833A1 (fr) 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
JPS5488277A JPS5488277A (en) 1979-07-13
JPS631305B2 true JPS631305B2 (en, 2012) 1988-01-12

Family

ID=26220343

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15380478A Granted JPS5488277A (en) 1977-12-15 1978-12-14 Novel derivative of 22**44quinolinyl* amino** 55fluorobenzoic acid*its manufacture and pharmaceutical composition containing it

Country Status (21)

Country Link
US (1) US4233305A (en, 2012)
JP (1) JPS5488277A (en, 2012)
AR (1) AR224116A1 (en, 2012)
AT (1) AT365578B (en, 2012)
AU (1) AU520983B2 (en, 2012)
CA (1) CA1115276A (en, 2012)
CH (1) CH636350A5 (en, 2012)
DE (1) DE2854341A1 (en, 2012)
DK (1) DK149845C (en, 2012)
ES (1) ES475686A1 (en, 2012)
FI (1) FI70574C (en, 2012)
GB (1) GB2010243B (en, 2012)
HU (1) HU177031B (en, 2012)
IE (1) IE47618B1 (en, 2012)
IL (1) IL56156A (en, 2012)
IT (1) IT1107671B (en, 2012)
LU (1) LU80660A1 (en, 2012)
NL (1) NL7812206A (en, 2012)
PT (1) PT68916A (en, 2012)
SE (1) SE448091B (en, 2012)
SU (1) SU837322A3 (en, 2012)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6322584A (ja) * 1986-07-15 1988-01-30 Senjiyu Seiyaku Kk １−ハイドロキシ−５−オキソ−５Ｈ−ピリド〔３，２−ａ〕フエノキサジン−３−カルボン酸エステル類
IL89029A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5578607A (en) * 1993-12-17 1996-11-26 The Procter & Gamble Company 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3232944A (en) * 1966-02-01 Monoglycerides 0f (carbgxy pl-ienyl amtno) chlgroqukngltnes
CH408915A (fr) * 1962-02-16 1966-03-15 Roussel Uclaf Procédé de préparation d'un nouveau composé utilisable, notamment, pour le traitement des manifestations inflammatoires et/ou douloureuses
CA731646A (en) * 1962-05-08 1966-04-05 Roussel-Uclaf 4-(2'(.beta.-MORPHOLYLETHOXYCARBONYL) PHENYLAMINE) 7-CHLORO QUINOLEINE ET SES SELS, AINSI QUE LEUR PROCEDE DE PREPARATION
FR6935M (en, 2012) * 1967-12-29 1969-05-05
FR7870M (en, 2012) * 1968-11-08 1970-04-27
ZA726593B (en) * 1971-10-19 1973-06-27 Abbott Lab Novel derivatives of 2,3-dihydroxypropyl-n-(7 or 8-chloro-4-quinolinyl)anthranilate
CH585221A5 (en, 2012) * 1972-07-28 1977-02-28 Synthelabo
US3971789A (en) * 1972-10-21 1976-07-27 John Wyeth & Brother Limited O-(4-Quinolylamino)benzamides
FR2233059B1 (en, 2012) * 1973-06-13 1976-09-03 Roussel Uclaf
GB1474296A (en) * 1975-01-23 1977-05-18 Wyeth John & Brother Ltd 4-aminoquinoline derivatives

Also Published As

Publication number Publication date
AT365578B (de) 1982-01-25
SE448091B (sv) 1987-01-19
DK561278A (da) 1979-06-16
CA1115276A (fr) 1981-12-29
DK149845B (da) 1986-10-13
ES475686A1 (es) 1979-04-16
FI70574C (fi) 1986-09-24
SE7811839L (sv) 1979-06-16
SU837322A3 (ru) 1981-06-07
AR224116A1 (es) 1981-10-30
DE2854341C2 (en, 2012) 1990-05-23
GB2010243A (en) 1979-06-27
LU80660A1 (fr) 1979-07-20
GB2010243B (en) 1982-05-19
HU177031B (hu) 1981-06-28
US4233305A (en) 1980-11-11
JPS5488277A (en) 1979-07-13
FI70574B (fi) 1986-06-06
DK149845C (da) 1987-03-02
IE47618B1 (en) 1984-05-02
NL7812206A (nl) 1979-06-19
AU520983B2 (en) 1982-03-11
IL56156A0 (en) 1979-03-12
IT7852296A0 (it) 1978-12-14
DE2854341A1 (de) 1979-06-28
AU4252878A (en) 1979-06-21
IE782476L (en) 1979-06-15
ATA897378A (de) 1981-06-15
CH636350A5 (fr) 1983-05-31
PT68916A (fr) 1979-01-01
IL56156A (en) 1984-11-30
FI783833A7 (fi) 1979-06-16
IT1107671B (it) 1985-11-25

Similar Documents

Publication Publication Date Title
US4107310A (en) Quinoline-3-carboxamides
JPS626703B2 (en, 2012)
JPS6126539B2 (en, 2012)
BG61323B2 (bg) Производни на пиперидина,тяхното получаване и използването им като лекарства
EP0177392A1 (fr) Nouvelles (pyridyl-2)-1 pipérazines, leur procédé de préparation et leur application en thérapeutique
FR2493315A1 (fr) Derive de piperazine, procede pour sa preparation et composition analgesique en contenant
JPS6216942B2 (en, 2012)
FR2480284A1 (fr) Amines antihypertensives, leur procede de preparation et compositions antihypertensives en contenant.
JPS6322049A (ja) 不可逆的ド−パミン−β−ヒドロキシラ−ゼ抑制剤
WO1984000546A1 (fr) Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
EP0231709A2 (fr) Nouvelles phényl-naphtyridines fonctionnalisées en position-3, leur procédé de préparation, médicaments les contenant, notamment anti-ulcères
FR2549058A1 (fr) Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
CA1139763A (fr) Procede d'obtention de nouveaux aryltrifluoroethanols
JPS631305B2 (en, 2012)
FR2567520A1 (fr) Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres
US3530137A (en) Certain alkyl and aryl ethers and thioethers of tropine and derivatives thereof
FR2460934A1 (fr) Derives d'isoquinoleine contenant du soufre, procedes pour leur preparation et compositions pharmaceutiques les contenant
EP0032856B1 (fr) Nouveaux dérivés de dihydro-2,3-imidazo(1,2-b)pyridazines, leur procédé de préparation et leur application en thérapeutique
US4221798A (en) Hypotensive 2-heterocycloamino-imidazolines
EP0005091B1 (fr) Nouvelles pipérazines monosubstituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
FR2462438A1 (fr) Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments
JPS6229585A (ja) エーテル化若しくはエステル化しうるジヒドロキシ基により位置２で置換された４―ｏｈキノリンカルボン酸の新規の誘導体、その製造方法、及び医薬としてのその使用
FR2649981A1 (fr) Derives de dihydropyrimidothiazine, leur procede de preparation et compositions pharmaceutiques les contenant
CA1211441A (fr) Procede de preparation de nouvelles piperidinoguanidines substituees, et des compositions pharmaceutiques en renfermant
JPS62108863A (ja) ２−ピリジル酢酸誘導体、その製法およびそれを含む医薬