FR2411833A1 - Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament - Google Patents

Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament

Info

Publication number
FR2411833A1
FR2411833A1 FR7737836A FR7737836A FR2411833A1 FR 2411833 A1 FR2411833 A1 FR 2411833A1 FR 7737836 A FR7737836 A FR 7737836A FR 7737836 A FR7737836 A FR 7737836A FR 2411833 A1 FR2411833 A1 FR 2411833A1
Authority
FR
France
Prior art keywords
alkyl
pains
quinolylamino
fluoro
benzoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7737836A
Other languages
English (en)
Other versions
FR2411833B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7737836A priority Critical patent/FR2411833A1/fr
Priority to SE7811839A priority patent/SE448091B/sv
Priority to ES475686A priority patent/ES475686A1/es
Priority to US05/966,964 priority patent/US4233305A/en
Priority to SU782696357A priority patent/SU837322A3/ru
Priority to IL56156A priority patent/IL56156A/xx
Priority to FI783833A priority patent/FI70574C/fi
Priority to IT52296/78A priority patent/IT1107671B/it
Priority to GB7848546A priority patent/GB2010243B/en
Priority to PT68916A priority patent/PT68916A/fr
Priority to AU42528/78A priority patent/AU520983B2/en
Priority to IE2476/78A priority patent/IE47618B1/en
Priority to DK561278A priority patent/DK149845C/da
Priority to HU78RO1003A priority patent/HU177031B/hu
Priority to JP15380478A priority patent/JPS5488277A/ja
Priority to LU80660A priority patent/LU80660A1/fr
Priority to CA317,952A priority patent/CA1115276A/fr
Priority to AR274807A priority patent/AR224116A1/es
Priority to NL7812206A priority patent/NL7812206A/xx
Priority to DE19782854341 priority patent/DE2854341A1/de
Priority to CH1279478A priority patent/CH636350A5/fr
Priority to AT0897378A priority patent/AT365578B/de
Publication of FR2411833A1 publication Critical patent/FR2411833A1/fr
Application granted granted Critical
Publication of FR2411833B1 publication Critical patent/FR2411833B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION A POUR OBJET LES COMPOSES DE FORMULE I: (CF DESSIN DANS BOPI) DANS LAQUELLE X, EN POSITION 8, REPRESENTE UN ATOME DE CHLORE OU UN RADICAL TRIFLUOROMETHYLE ET R UN ATOME D'HYDROGENE OU UN GROUPEMENT ESTERIFIANT, LEURS SELS AVEC LES ACIDES, AINSI QUE LEURS SELS AVEC LES BASES QUAND R REPRESENTE UN ATOME D'HYDROGENE.
FR7737836A 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament Granted FR2411833A1 (fr)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FR7737836A FR2411833A1 (fr) 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament
SE7811839A SE448091B (sv) 1977-12-15 1978-11-16 Nya 2-/(4-kinolinyl)-amino/-5-fluorbensoesyraderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa derivat
ES475686A ES475686A1 (es) 1977-12-15 1978-12-04 Procedimiento de preparacion de nuevos derivados del acido 2-(4-quinoleinil)-amino-5-fluorobenzoico.
US05/966,964 US4233305A (en) 1977-12-15 1978-12-06 Novel derivatives of 2-(4-quinolinylamino)-5-fluoro-benzoic acids
SU782696357A SU837322A3 (ru) 1977-12-15 1978-12-07 Способ получени производных 2-/(4-ХиНОлил)АМиНО/-5-фТОРбЕНзОй-НОй КиСлОТы или иХ СОлЕй C КиСлО-ТАМи
IL56156A IL56156A (en) 1977-12-15 1978-12-08 Derivatives of 2-(4-quinolinyl)amino 5-fluorobenzoic acid,process for preparing them and pharmaceutical compositions containing them
FI783833A FI70574C (fi) 1977-12-15 1978-12-13 Foerfarande foer framstaellning av nya farmaceutiskt anvaendbara derivat av 2-7(4-kinolinyl)-amino/-5-fluorbensoesyra
CA317,952A CA1115276A (fr) 1977-12-15 1978-12-14 Procede de preparation de nouveaux derives de l'acide 2/(4-quinoleinyl) amino/ 5-fluorobenzoique
PT68916A PT68916A (fr) 1977-12-15 1978-12-14 Procede de preparation de nouveaux derives de l'acide 2-(4-quinoleinyl)-amino -5 fluoro-benzoique
AU42528/78A AU520983B2 (en) 1977-12-15 1978-12-14 Derivatives of 2-(4 quinolinyl)amino) 5-fluoro benzoic acid
IT52296/78A IT1107671B (it) 1977-12-15 1978-12-14 Derivati dell'acido 2-4-chinolil ammino 5-fluoro-benzoico procedimento per la loro produzione loro impiego in qualita' di medicamenti e composizioni farmaceutiche che li contengono
DK561278A DK149845C (da) 1977-12-15 1978-12-14 Analogifremgangsmaade til fremstilling af 2-((4-quinolinyl)-amino)-5-flourbenzoesyrederivater
HU78RO1003A HU177031B (hu) 1977-12-15 1978-12-14 Sposob poluchenija novykh 2-/4-khinolinil-amino/-5-ftoro-benzojnoj kisloty
JP15380478A JPS5488277A (en) 1977-12-15 1978-12-14 Novel derivative of 22**44quinolinyl* amino** 55fluorobenzoic acid*its manufacture and pharmaceutical composition containing it
LU80660A LU80660A1 (fr) 1977-12-15 1978-12-14 Nouveaux derives de l'acide 2-((4-quinoleinyl)amino)5-fluorobenzoique,leur procede de preparation et leur application
GB7848546A GB2010243B (en) 1977-12-15 1978-12-14 2-(quinolin-4-ylamino)-5-fluorobenzoic acid derivatives
AR274807A AR224116A1 (es) 1977-12-15 1978-12-14 Procedimiento de preparacion de nuevos derivados del acido 2-((4-quinoleinil)-amino)-5-fluorobenzoico
IE2476/78A IE47618B1 (en) 1977-12-15 1978-12-14 2-(quinolin-4-ylamino)-5-fluorobenzoic acid derivatives
NL7812206A NL7812206A (nl) 1977-12-15 1978-12-15 Nieuwe 2-((4-chinolinyl)amino)-5-fluorbenzoeezuurderiva-ten, hun bereiding, hun toepassing als geneesmiddelen en farmaceutische preparaten, die deze nieuwe stoffen bevatten.
DE19782854341 DE2854341A1 (de) 1977-12-15 1978-12-15 Neue derivate der 2- eckige klammer auf (4-chinolinyl)-amino eckige klammer zu -5-fluorbenzoesaeure, verfahren zu deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden pharmazeutischen zusammensetzungen
CH1279478A CH636350A5 (fr) 1977-12-15 1978-12-15 Derives de l'acide 2-/(4-quinoleinyl) amino/ 5-fluorobenzoique, leurs procedes de preparation et les compositions pharmaceutiques les renfermant.
AT0897378A AT365578B (de) 1977-12-15 1978-12-15 Verfahren zur herstellung neuer derivate der 2((4-chinolinyl)amino)-5-fluorbenzoesaeure und ihrersalze

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7737836A FR2411833A1 (fr) 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
FR2411833A1 true FR2411833A1 (fr) 1979-07-13
FR2411833B1 FR2411833B1 (fr) 1980-11-14

Family

ID=9198894

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7737836A Granted FR2411833A1 (fr) 1977-12-15 1977-12-15 Nouveaux derives de l'acide 2(/4-quinoleinyl/amino) 5-fluoro benzoique, leur procede de preparation et leur application comme medicament

Country Status (1)

Country Link
FR (1) FR2411833A1 (fr)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/73 *

Also Published As

Publication number Publication date
FR2411833B1 (fr) 1980-11-14

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