ES311825A1 - Procedimiento de preparaciën de derivados de la piperacina - Google Patents
Procedimiento de preparaciën de derivados de la piperacinaInfo
- Publication number
- ES311825A1 ES311825A1 ES0311825A ES311825A ES311825A1 ES 311825 A1 ES311825 A1 ES 311825A1 ES 0311825 A ES0311825 A ES 0311825A ES 311825 A ES311825 A ES 311825A ES 311825 A1 ES311825 A1 ES 311825A1
- Authority
- ES
- Spain
- Prior art keywords
- cooh
- reacting
- general formula
- compound
- trifluoromethylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Punching Or Piercing (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15439/64A GB1105522A (en) | 1964-04-14 | 1964-04-14 | N-phenylpiperazine compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES311825A1 true ES311825A1 (es) | 1966-02-01 |
Family
ID=10059167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0311825A Expired ES311825A1 (es) | 1964-04-14 | 1965-04-14 | Procedimiento de preparaciën de derivados de la piperacina |
Country Status (11)
Country | Link |
---|---|
US (1) | US3326916A (es) |
AT (4) | AT257618B (es) |
BE (1) | BE662455A (es) |
CH (2) | CH444869A (es) |
DE (1) | DE1595933A1 (es) |
ES (1) | ES311825A1 (es) |
FR (1) | FR4239M (es) |
GB (1) | GB1105522A (es) |
IL (1) | IL23338A (es) |
NL (1) | NL6504788A (es) |
NO (1) | NO117423B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789255A (fr) * | 1971-09-30 | 1973-03-26 | Synthelabo | N-cyano-ethyl n'-m-chlorophenyl piperazine et ses |
FR2201084B1 (es) * | 1972-09-29 | 1975-10-31 | Bouchara Emile | |
US4202898A (en) * | 1978-06-05 | 1980-05-13 | Synthelabo | Method of treating anxiety and depression |
JPS574921A (en) * | 1980-06-13 | 1982-01-11 | Chugai Pharmaceut Co Ltd | Remedy for cardiovascular disorder |
DE19734516A1 (de) * | 1997-08-08 | 1999-02-11 | Bayer Ag | Verfahren zur Herstellung von N-Aryl-N'-alkyl-piperazinen |
SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
SE0401465D0 (sv) * | 2004-06-08 | 2004-06-08 | Carlsson A Research Ab | New substituted piperdines as modulators of dopamine neurotransmission |
MXPA06013941A (es) * | 2004-06-08 | 2007-12-10 | Neurosearch Sweden Ab | Fenilpiperidinas disustituidas, novedosas, como moduladores de la neurotransmision de dopamina y serotonina. |
CA2569843A1 (en) | 2004-06-08 | 2005-12-22 | A. Carlsson Research Ab | New disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission |
US7851629B2 (en) * | 2004-06-08 | 2010-12-14 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission |
WO2006040156A1 (en) * | 2004-10-13 | 2006-04-20 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-sulfonylphenyl)-piperidines |
EP1802573B1 (en) * | 2004-10-13 | 2016-09-28 | Teva Pharmaceuticals International GmbH | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
SE529246C2 (sv) * | 2005-10-13 | 2007-06-12 | Neurosearch Sweden Ab | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission |
US9012476B2 (en) | 2011-12-08 | 2015-04-21 | IVAX International GmbH | Hydrobromide salt of pridopidine |
WO2013152105A1 (en) | 2012-04-04 | 2013-10-10 | IVAX International GmbH | Pharmaceutical compositions for combination therapy |
-
0
- BE BE662455D patent/BE662455A/xx unknown
-
1964
- 1964-04-14 AT AT924366A patent/AT257618B/de active
- 1964-04-14 GB GB15439/64A patent/GB1105522A/en not_active Expired
-
1965
- 1965-04-07 US US446417A patent/US3326916A/en not_active Expired - Lifetime
- 1965-04-09 CH CH263867A patent/CH444869A/fr unknown
- 1965-04-09 CH CH498665A patent/CH435295A/fr unknown
- 1965-04-12 NO NO157660A patent/NO117423B/no unknown
- 1965-04-12 IL IL23338A patent/IL23338A/en unknown
- 1965-04-14 FR FR13237A patent/FR4239M/fr not_active Expired
- 1965-04-14 AT AT924466A patent/AT257619B/de active
- 1965-04-14 ES ES0311825A patent/ES311825A1/es not_active Expired
- 1965-04-14 AT AT346065A patent/AT262293B/de active
- 1965-04-14 NL NL6504788A patent/NL6504788A/xx unknown
- 1965-04-14 AT AT924566A patent/AT257620B/de active
- 1965-04-14 DE DE19651595933 patent/DE1595933A1/de active Pending
Also Published As
Publication number | Publication date |
---|---|
US3326916A (en) | 1967-06-20 |
DE1595933A1 (de) | 1970-02-12 |
FR4239M (es) | 1966-06-20 |
NL6504788A (es) | 1965-10-15 |
AT257620B (de) | 1967-10-10 |
BE662455A (es) | |
CH435295A (fr) | 1967-05-15 |
IL23338A (en) | 1968-08-22 |
CH444869A (fr) | 1967-10-15 |
GB1105522A (en) | 1968-03-06 |
AT257619B (de) | 1967-10-10 |
AT257618B (de) | 1967-10-10 |
AT262293B (de) | 1968-06-10 |
NO117423B (es) | 1969-08-11 |
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