AT262293B - Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen - Google Patents

Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen

Info

Publication number
AT262293B
AT262293B AT346065A AT346065A AT262293B AT 262293 B AT262293 B AT 262293B AT 346065 A AT346065 A AT 346065A AT 346065 A AT346065 A AT 346065A AT 262293 B AT262293 B AT 262293B
Authority
AT
Austria
Prior art keywords
phenylpiperazines
bases
preparation
new
acid addition
Prior art date
Application number
AT346065A
Other languages
English (en)
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Application granted granted Critical
Publication of AT262293B publication Critical patent/AT262293B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Punching Or Piercing (AREA)
AT346065A 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen AT262293B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15439/64A GB1105522A (en) 1964-04-14 1964-04-14 N-phenylpiperazine compounds

Publications (1)

Publication Number Publication Date
AT262293B true AT262293B (de) 1968-06-10

Family

ID=10059167

Family Applications (4)

Application Number Title Priority Date Filing Date
AT924366A AT257618B (de) 1964-04-14 1964-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen
AT924466A AT257619B (de) 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen
AT346065A AT262293B (de) 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen
AT924566A AT257620B (de) 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT924366A AT257618B (de) 1964-04-14 1964-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen
AT924466A AT257619B (de) 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT924566A AT257620B (de) 1964-04-14 1965-04-14 Verfahren zur Herstellung von neuen N-Phenylpiperazinen

Country Status (11)

Country Link
US (1) US3326916A (de)
AT (4) AT257618B (de)
BE (1) BE662455A (de)
CH (2) CH435295A (de)
DE (1) DE1595933A1 (de)
ES (1) ES311825A1 (de)
FR (1) FR4239M (de)
GB (1) GB1105522A (de)
IL (1) IL23338A (de)
NL (1) NL6504788A (de)
NO (1) NO117423B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789255A (fr) * 1971-09-30 1973-03-26 Synthelabo N-cyano-ethyl n'-m-chlorophenyl piperazine et ses
FR2201084B1 (de) * 1972-09-29 1975-10-31 Bouchara Emile
US4202898A (en) * 1978-06-05 1980-05-13 Synthelabo Method of treating anxiety and depression
JPS574921A (en) * 1980-06-13 1982-01-11 Chugai Pharmaceut Co Ltd Remedy for cardiovascular disorder
DE19734516A1 (de) * 1997-08-08 1999-02-11 Bayer Ag Verfahren zur Herstellung von N-Aryl-N'-alkyl-piperazinen
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
SE0401465D0 (sv) * 2004-06-08 2004-06-08 Carlsson A Research Ab New substituted piperdines as modulators of dopamine neurotransmission
AU2005251906B2 (en) 2004-06-08 2011-03-31 Nsab, Filial Af Neurosearch Sweden Ab, Sverige New disubstituted phenylpiperidines/piperazines as modulators of dopamine neurotransmission
US7851629B2 (en) * 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
DE602005021641D1 (de) * 2004-06-08 2010-07-15 Nsab, Filial Af Neurosearch Sweden Ab Neue disubstituierte phenylpiperidine und piperazine als modulatoren der dopamin-neurotransmission
WO2006040155A1 (en) * 2004-10-13 2006-04-20 Neurosearch Sweden Ab Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine
JP2008515952A (ja) * 2004-10-13 2008-05-15 ニューロサーチ スウェーデン アクチボラゲット 4−(3−スルホニルフェニル)−ピペリジンの合成方法
SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
MX347209B (es) 2011-12-08 2017-04-19 Teva Pharmaceuticals Int Gmbh La sal de bromhidrato de pridopidina.
MX2014011971A (es) 2012-04-04 2015-01-16 Ivax Int Gmbh Composiciones farmaceuticas para terapia de combinacion.

Also Published As

Publication number Publication date
AT257618B (de) 1967-10-10
AT257620B (de) 1967-10-10
IL23338A (en) 1968-08-22
DE1595933A1 (de) 1970-02-12
NO117423B (de) 1969-08-11
CH435295A (fr) 1967-05-15
FR4239M (de) 1966-06-20
AT257619B (de) 1967-10-10
GB1105522A (en) 1968-03-06
ES311825A1 (es) 1966-02-01
US3326916A (en) 1967-06-20
BE662455A (de)
CH444869A (fr) 1967-10-15
NL6504788A (de) 1965-10-15

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