AT262293B - Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen - Google Patents
Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit BasenInfo
- Publication number
- AT262293B AT262293B AT346065A AT346065A AT262293B AT 262293 B AT262293 B AT 262293B AT 346065 A AT346065 A AT 346065A AT 346065 A AT346065 A AT 346065A AT 262293 B AT262293 B AT 262293B
- Authority
- AT
- Austria
- Prior art keywords
- phenylpiperazines
- bases
- preparation
- new
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Punching Or Piercing (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB15439/64A GB1105522A (en) | 1964-04-14 | 1964-04-14 | N-phenylpiperazine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT262293B true AT262293B (de) | 1968-06-10 |
Family
ID=10059167
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT924366A AT257618B (de) | 1964-04-14 | 1964-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
| AT924566A AT257620B (de) | 1964-04-14 | 1965-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
| AT924466A AT257619B (de) | 1964-04-14 | 1965-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
| AT346065A AT262293B (de) | 1964-04-14 | 1965-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen, ihren Säureadditionssalzen und nichttoxischen Salzen mit Basen |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT924366A AT257618B (de) | 1964-04-14 | 1964-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
| AT924566A AT257620B (de) | 1964-04-14 | 1965-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
| AT924466A AT257619B (de) | 1964-04-14 | 1965-04-14 | Verfahren zur Herstellung von neuen N-Phenylpiperazinen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3326916A (de) |
| AT (4) | AT257618B (de) |
| BE (1) | BE662455A (de) |
| CH (2) | CH435295A (de) |
| DE (1) | DE1595933A1 (de) |
| ES (1) | ES311825A1 (de) |
| FR (1) | FR4239M (de) |
| GB (1) | GB1105522A (de) |
| IL (1) | IL23338A (de) |
| NL (1) | NL6504788A (de) |
| NO (1) | NO117423B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE789255A (fr) * | 1971-09-30 | 1973-03-26 | Synthelabo | N-cyano-ethyl n'-m-chlorophenyl piperazine et ses |
| FR2201084B1 (de) * | 1972-09-29 | 1975-10-31 | Bouchara Emile | |
| US4202898A (en) * | 1978-06-05 | 1980-05-13 | Synthelabo | Method of treating anxiety and depression |
| JPS574921A (en) * | 1980-06-13 | 1982-01-11 | Chugai Pharmaceut Co Ltd | Remedy for cardiovascular disorder |
| DE19734516A1 (de) * | 1997-08-08 | 1999-02-11 | Bayer Ag | Verfahren zur Herstellung von N-Aryl-N'-alkyl-piperazinen |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| ES2346452T3 (es) | 2004-06-08 | 2010-10-15 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Nuevas fenilpiperidinas/piperazinas disustituidas utilizadas como moduladores de la neurotransmision de la dopamina. |
| SE0401465D0 (sv) * | 2004-06-08 | 2004-06-08 | Carlsson A Research Ab | New substituted piperdines as modulators of dopamine neurotransmission |
| DE602005021641D1 (de) * | 2004-06-08 | 2010-07-15 | Nsab, Filial Af Neurosearch Sweden Ab | Neue disubstituierte phenylpiperidine und piperazine als modulatoren der dopamin-neurotransmission |
| US7851629B2 (en) * | 2004-06-08 | 2010-12-14 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission |
| JP2008515952A (ja) * | 2004-10-13 | 2008-05-15 | ニューロサーチ スウェーデン アクチボラゲット | ４−（３−スルホニルフェニル）−ピペリジンの合成方法 |
| ES2659577T3 (es) * | 2004-10-13 | 2018-03-16 | Teva Pharmaceuticals International Gmbh | Proceso para la síntesis de 4-(3-metanosulfonilfenil)-1-N-propil-piperidina |
| SE529246C2 (sv) * | 2005-10-13 | 2007-06-12 | Neurosearch Sweden Ab | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission |
| UY34503A (es) | 2011-12-08 | 2013-07-31 | Ivax Int Gmbh | ?sal de bromhidrato de pridopidina? |
| US20130267552A1 (en) | 2012-04-04 | 2013-10-10 | IVAX International GmbH | Pharmaceutical compositions for combination therapy |
-
0
- BE BE662455D patent/BE662455A/xx unknown
-
1964
- 1964-04-14 GB GB15439/64A patent/GB1105522A/en not_active Expired
- 1964-04-14 AT AT924366A patent/AT257618B/de active
-
1965
- 1965-04-07 US US446417A patent/US3326916A/en not_active Expired - Lifetime
- 1965-04-09 CH CH498665A patent/CH435295A/fr unknown
- 1965-04-09 CH CH263867A patent/CH444869A/fr unknown
- 1965-04-12 IL IL23338A patent/IL23338A/en unknown
- 1965-04-12 NO NO157660A patent/NO117423B/no unknown
- 1965-04-14 AT AT924566A patent/AT257620B/de active
- 1965-04-14 ES ES0311825A patent/ES311825A1/es not_active Expired
- 1965-04-14 AT AT924466A patent/AT257619B/de active
- 1965-04-14 AT AT346065A patent/AT262293B/de active
- 1965-04-14 NL NL6504788A patent/NL6504788A/xx unknown
- 1965-04-14 DE DE19651595933 patent/DE1595933A1/de active Pending
- 1965-04-14 FR FR13237A patent/FR4239M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT257619B (de) | 1967-10-10 |
| IL23338A (en) | 1968-08-22 |
| CH444869A (fr) | 1967-10-15 |
| CH435295A (fr) | 1967-05-15 |
| US3326916A (en) | 1967-06-20 |
| NL6504788A (de) | 1965-10-15 |
| NO117423B (de) | 1969-08-11 |
| FR4239M (de) | 1966-06-20 |
| AT257618B (de) | 1967-10-10 |
| ES311825A1 (es) | 1966-02-01 |
| AT257620B (de) | 1967-10-10 |
| DE1595933A1 (de) | 1970-02-12 |
| BE662455A (de) | |
| GB1105522A (en) | 1968-03-06 |
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