GB1084439A - Improvements in or relating to heteroeyclic compounds and the manufacture thereof - Google Patents
Improvements in or relating to heteroeyclic compounds and the manufacture thereofInfo
- Publication number
- GB1084439A GB1084439A GB5160664A GB5160664A GB1084439A GB 1084439 A GB1084439 A GB 1084439A GB 5160664 A GB5160664 A GB 5160664A GB 5160664 A GB5160664 A GB 5160664A GB 1084439 A GB1084439 A GB 1084439A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- alkyl
- mono
- prepared
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel compounds of the general formula <FORM:1084439/C2/1> (wherein n is 1, 2, or 3, and R1 and R2 each represent a C1- 8 alkyl, C7- 12 aralkyl, phenyl, mono- or di-(C1- 8 alkyl or alkoxy) phenyl or mono- or di-halophenyl radical, but are not both phenyl or substituted phenyl, or R1 and R2 jointly represent an alkylene, oxoalkylene, thioalkylene or N-(C1- 8 alkyl)-azoalkylene radical forming with N a 5-7 membered heterocyclic ring) are prepared by condensing p-benzoquinone with a cycloalkenamine of the formula <FORM:1084439/C2/2> The products may be esterified with C1- 6 alkanoic acids (or derivatives thereof), and both the free phenols and the esters may be converted to acid addition salts, or to N-oxides by treatment with a peroxidizing agent. Cycloalkenamines of the second general formula above are prepared by reacting cyclopentanone, cyclohexanone or cycloheptanone with a secondary amine R1.NH.R2.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33493463A | 1963-12-31 | 1963-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1084439A true GB1084439A (en) | 1967-09-20 |
Family
ID=23309512
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5160664A Expired GB1084439A (en) | 1963-12-31 | 1964-12-18 | Improvements in or relating to heteroeyclic compounds and the manufacture thereof |
GB1650067A Expired GB1084440A (en) | 1963-12-31 | 1964-12-18 | Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1650067A Expired GB1084440A (en) | 1963-12-31 | 1964-12-18 | Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof |
Country Status (4)
Country | Link |
---|---|
CH (1) | CH462803A (en) |
FR (1) | FR1458097A (en) |
GB (2) | GB1084439A (en) |
NL (1) | NL6415270A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2613365A1 (en) * | 1987-04-01 | 1988-10-07 | Adir | NOVEL DERIVATIVES OF AMINO TETRAHYDRO-5, 6, 7, 8 NAPHTO (2, 3B) FURANNE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2613364A1 (en) * | 1987-04-01 | 1988-10-07 | Adir | NOVEL TRICYCLIC AMINES DERIVED FROM TETRAHYDRO-5, 6, 7, 8 NAPHTO (2,3B) DIHYDRO-2,3-FURANNE, AND TETRAHYDRO-6,7,8,9-5H-BENZOCYCLOHEPTA (2,3B) DIHYDRO-2, 3 FURANNE, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668690A (en) * | 1985-12-30 | 1987-05-26 | Hoechst Roussel Pharmaceuticals Inc. | 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants |
-
1964
- 1964-12-18 GB GB5160664A patent/GB1084439A/en not_active Expired
- 1964-12-18 CH CH1633864A patent/CH462803A/en unknown
- 1964-12-18 GB GB1650067A patent/GB1084440A/en not_active Expired
- 1964-12-30 FR FR495A patent/FR1458097A/en not_active Expired
- 1964-12-30 NL NL6415270A patent/NL6415270A/xx unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2613365A1 (en) * | 1987-04-01 | 1988-10-07 | Adir | NOVEL DERIVATIVES OF AMINO TETRAHYDRO-5, 6, 7, 8 NAPHTO (2, 3B) FURANNE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2613364A1 (en) * | 1987-04-01 | 1988-10-07 | Adir | NOVEL TRICYCLIC AMINES DERIVED FROM TETRAHYDRO-5, 6, 7, 8 NAPHTO (2,3B) DIHYDRO-2,3-FURANNE, AND TETRAHYDRO-6,7,8,9-5H-BENZOCYCLOHEPTA (2,3B) DIHYDRO-2, 3 FURANNE, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
EP0286515A1 (en) * | 1987-04-01 | 1988-10-12 | Adir Et Compagnie | 5,6,7,8-Tetrahydro-naphtho [2,3b]-2,3-dihydrofuran and 6,7,8,9-tetrahydro-5H-benzocyclohepta [2,3b]-2,3-dihydro furan tricyclic amine derivatives, processes for their preparation and pharmaceutical compositions containing them |
EP0286516A1 (en) * | 1987-04-01 | 1988-10-12 | Adir Et Compagnie | Amino-5,6,7,8-tetrahydro-naphtho[2,3b]furan derivatives, processes for their preparation and pharmaceutical compositions containing them |
GR880100208A (en) * | 1987-04-01 | 1989-01-31 | Adir | Preparation method of new aminotetrahydro-5,6,7,8,naphtho (2,3b) furane |
GR880100207A (en) * | 1987-04-01 | 1989-01-31 | Adir | Preparation of new tricyclic amino derivatives of tetrahydro-5,6,7 naphtho-2,3 |
Also Published As
Publication number | Publication date |
---|---|
CH462803A (en) | 1968-09-30 |
GB1084440A (en) | 1967-09-20 |
NL6415270A (en) | 1965-07-02 |
FR1458097A (en) | 1966-11-10 |
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