JPS6237034B2 - - Google Patents

Info

Publication number
JPS6237034B2
JPS6237034B2 JP59048963A JP4896384A JPS6237034B2 JP S6237034 B2 JPS6237034 B2 JP S6237034B2 JP 59048963 A JP59048963 A JP 59048963A JP 4896384 A JP4896384 A JP 4896384A JP S6237034 B2 JPS6237034 B2 JP S6237034B2
Authority
JP
Japan
Prior art keywords
group
formula
dimethylheptyl
piperidinol
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP59048963A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59176255A (ja
Inventor
Rosu Jonson Maikeru
Shaaman Meruin Juniaa Roorensu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPS59176255A publication Critical patent/JPS59176255A/ja
Publication of JPS6237034B2 publication Critical patent/JPS6237034B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP59048963A 1983-03-14 1984-03-14 ２−〔２−ヒドロキシ−４−（置換）フエニル〕ピペリジン化合物 Granted JPS59176255A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US474957 1983-03-14
US06/474,957 US4529732A (en) 1983-03-14 1983-03-14 2-[2-Hydroxy-4-(substituted)phenyl]piperidines

Publications (2)

Publication Number Publication Date
JPS59176255A JPS59176255A (ja) 1984-10-05
JPS6237034B2 true JPS6237034B2 (en, 2012) 1987-08-10

Family

ID=23885667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59048963A Granted JPS59176255A (ja) 1983-03-14 1984-03-14 ２−〔２−ヒドロキシ−４−（置換）フエニル〕ピペリジン化合物

Country Status (8)

Country Link
US (1) US4529732A (en, 2012)
EP (1) EP0119087B1 (en, 2012)
JP (1) JPS59176255A (en, 2012)
AT (1) ATE37712T1 (en, 2012)
DE (1) DE3474445D1 (en, 2012)
DK (1) DK113984A (en, 2012)
GR (1) GR81837B (en, 2012)
IE (1) IE57030B1 (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
FR2793246B1 (fr) * 1999-05-03 2001-06-29 Adir Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2005536554A (ja) * 2002-08-23 2005-12-02 ユニバーシティ オブ コネチカット 新規なビフェニル及びビフェニル様カンナビノイド
WO2007127711A2 (en) * 2006-04-24 2007-11-08 Allergan, Inc. Abnormal cannabidiols as agents for lowering intraocular pressure
US7618966B2 (en) 2006-04-24 2009-11-17 Allergan, Inc. Abnormal Cannabidiols as agents for lowering intraocular pressure
US7612101B2 (en) 2006-04-24 2009-11-03 Allergan, Inc. Abnormal cannabidiols as agents for lowering intraocular pressure
US7718830B2 (en) 2006-04-24 2010-05-18 Allergan, Inc. Abnormal cannabidiols as agents for lowering intraocular pressure
JP2025522912A (ja) * 2022-07-06 2025-07-17 ヴィヴィディオン セラピューティクス， インコーポレイテッド Ｗｒｎヘリカーゼ阻害剤を含む医薬組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2498431A (en) * 1945-06-13 1950-02-21 Hoffmann La Roche 2-and 4-homocyclyl substituted piperidines
US3067204A (en) * 1959-09-16 1962-12-04 Smith Kline French Lab 2, 2-dimethyl-6-phenylpiperidine derivatives
FR1288025A (fr) * 1960-02-08 1962-03-24 Boehringer & Soehne Gmbh Procédé de préparation de nouvelles piperidones-(4) substituées en position 1, 2, 6 ou de leurs sels
US4147872A (en) * 1977-09-13 1979-04-03 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor
US4306097A (en) * 1977-09-13 1981-12-15 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents
US4216218A (en) * 1979-02-23 1980-08-05 American Hoechst Corporation Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines

Also Published As

Publication number Publication date
IE57030B1 (en) 1992-03-25
US4529732A (en) 1985-07-16
DK113984D0 (da) 1984-02-28
EP0119087B1 (en) 1988-10-05
GR81837B (en, 2012) 1984-12-12
JPS59176255A (ja) 1984-10-05
IE840624L (en) 1984-09-14
ATE37712T1 (de) 1988-10-15
EP0119087A1 (en) 1984-09-19
DK113984A (da) 1984-09-15
DE3474445D1 (en) 1988-11-10

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