JPS61502099A - 単量予充てん式注射器の製造方法および装置 - Google Patents
単量予充てん式注射器の製造方法および装置Info
- Publication number
- JPS61502099A JPS61502099A JP60502069A JP50206985A JPS61502099A JP S61502099 A JPS61502099 A JP S61502099A JP 60502069 A JP60502069 A JP 60502069A JP 50206985 A JP50206985 A JP 50206985A JP S61502099 A JPS61502099 A JP S61502099A
- Authority
- JP
- Japan
- Prior art keywords
- ampoule
- gas
- injector
- cavity
- syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 28
- 238000004519 manufacturing process Methods 0.000 title claims description 22
- 229940071643 prefilled syringe Drugs 0.000 title claims 11
- 239000003708 ampul Substances 0.000 claims description 177
- 239000003814 drug Substances 0.000 claims description 26
- 229940079593 drug Drugs 0.000 claims description 26
- 239000002245 particle Substances 0.000 claims description 20
- 239000002775 capsule Substances 0.000 claims description 16
- 238000010408 sweeping Methods 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 12
- 230000033001 locomotion Effects 0.000 claims description 10
- 238000002347 injection Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 230000002093 peripheral effect Effects 0.000 claims description 4
- 230000000630 rising effect Effects 0.000 claims description 3
- 238000013519 translation Methods 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 230000004308 accommodation Effects 0.000 claims 1
- 238000010276 construction Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000007789 gas Substances 0.000 description 120
- 239000007787 solid Substances 0.000 description 18
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 14
- 229910052760 oxygen Inorganic materials 0.000 description 14
- 239000001301 oxygen Substances 0.000 description 14
- 230000032258 transport Effects 0.000 description 11
- 238000010586 diagram Methods 0.000 description 9
- 238000007789 sealing Methods 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 8
- 238000003860 storage Methods 0.000 description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 description 4
- 230000006835 compression Effects 0.000 description 4
- 238000007906 compression Methods 0.000 description 4
- 230000002950 deficient Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000001569 carbon dioxide Substances 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 230000003014 reinforcing effect Effects 0.000 description 3
- 239000000356 contaminant Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000004447 silicone coating Substances 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/062—Carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH239984 | 1984-05-16 | ||
| CH2399/84-1 | 1984-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS61502099A true JPS61502099A (ja) | 1986-09-25 |
Family
ID=4232872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60502069A Pending JPS61502099A (ja) | 1984-05-16 | 1985-05-14 | 単量予充てん式注射器の製造方法および装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4703781A (https=) |
| EP (1) | EP0185027B1 (https=) |
| JP (1) | JPS61502099A (https=) |
| DE (1) | DE3579893D1 (https=) |
| WO (1) | WO1985005269A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE62637B1 (en) * | 1988-09-22 | 1995-02-22 | Eolas Irish Science & Tech | Apparatus for filling tubes |
| US5620425A (en) | 1993-11-03 | 1997-04-15 | Bracco International B.V. | Method for the preparation of pre-filled plastic syringes |
| FR2719018B1 (fr) * | 1994-04-26 | 1996-07-12 | Py Daniel C | Procédé pour remplir dans des conditions aseptiques un récipient obturé. |
| US5884457A (en) * | 1997-02-05 | 1999-03-23 | Smithkline Beecham Corporation | Method and apparatus for automatically producing a plurality of sterile liquid filled delivery devices |
| JP4132208B2 (ja) * | 1998-04-28 | 2008-08-13 | 大成化工株式会社 | 注射器用容器の製造装置及び注射器用容器の製造方法 |
| US7100646B2 (en) | 2000-02-11 | 2006-09-05 | Medical Instill Technologies, Inc. | Sealed containers and methods of making and filling same |
| US6604561B2 (en) | 2000-02-11 | 2003-08-12 | Medical Instill Technologies, Inc. | Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial |
| US7243689B2 (en) | 2000-02-11 | 2007-07-17 | Medical Instill Technologies, Inc. | Device with needle penetrable and laser resealable portion and related method |
| US7331944B2 (en) | 2000-10-23 | 2008-02-19 | Medical Instill Technologies, Inc. | Ophthalmic dispenser and associated method |
| MXPA03003556A (es) | 2000-10-23 | 2005-04-11 | Medical Instill Tech Inc | Distribuidor de fluido que tiene un frasco rigido y camara de aire interna flexible. |
| WO2003028785A2 (en) | 2001-10-03 | 2003-04-10 | Medical Instill Technologies, Inc. | Syringe and reconstitution syringe |
| WO2003033363A1 (en) | 2001-10-16 | 2003-04-24 | Medical Instill Technologies, Inc. | Dispenser with sealed chamber and one-way valve for providing metered amounts of substances |
| US7798185B2 (en) | 2005-08-01 | 2010-09-21 | Medical Instill Technologies, Inc. | Dispenser and method for storing and dispensing sterile food product |
| EP2433871A3 (en) | 2002-06-19 | 2012-07-11 | Medical Instill Technologies, Inc. | Sterile filling machine having needle filling station within e-beam chamber |
| USD522663S1 (en) | 2002-09-03 | 2006-06-06 | Medical Instill Technologies, Inc. | Vial |
| USD485365S1 (en) | 2002-09-03 | 2004-01-13 | Medical Instill Technologies, Inc. | Vial |
| USD561908S1 (en) | 2002-09-03 | 2008-02-12 | Medical Instill Technologies, Inc. | Vial |
| USD533670S1 (en) | 2002-09-03 | 2006-12-12 | Medical Instill Technologies, Inc. | Vial |
| DE10254762A1 (de) * | 2002-11-22 | 2004-06-09 | Transcoject Gesellschaft für medizinische Geräte mbH & Co. KG | Verfahren zur Herstellung und/oder Handhabung eines hochreinen Gegenstandes |
| JP4401355B2 (ja) * | 2003-01-28 | 2010-01-20 | メディカル・インスティル・テクノロジーズ・インコーポレイテッド | 熱シール可能なキャップを有するデバイスならびにそのデバイスを充填する装置及び方法 |
| WO2004096113A2 (en) | 2003-04-28 | 2004-11-11 | Medical Instill Technologies, Inc. | Container with valve assembly for filling and dispensing substances, and apparatus and method for filling |
| USD527463S1 (en) | 2004-01-27 | 2006-08-29 | Medical Instill Technologies, Inc. | Vial |
| CN100360197C (zh) * | 2005-01-13 | 2008-01-09 | 杭州市机械科学研究所有限公司 | 一次性注射针的上针管机 |
| US9033006B2 (en) | 2010-09-17 | 2015-05-19 | Nicholas J. Perazzo | Oral syringe packaging system for hospital pharmacies |
| US10220156B2 (en) * | 2012-04-25 | 2019-03-05 | Adar Medtech, Inc. | Single use injector |
| CN107635527B (zh) | 2015-03-10 | 2021-04-23 | 里珍纳龙药品有限公司 | 无菌刺穿系统和方法 |
| US10271935B2 (en) * | 2016-01-25 | 2019-04-30 | Team Technologies, Inc. | Unit dose package with ball seal |
| IL308643B2 (en) | 2017-05-05 | 2025-02-01 | Regeneron Pharma | Auto-injector |
| USD1007676S1 (en) | 2021-11-16 | 2023-12-12 | Regeneron Pharmaceuticals, Inc. | Wearable autoinjector |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2823500A (en) * | 1954-09-13 | 1958-02-18 | Pfizer & Co C | Machine for assembling hypodermic syringes |
| US2971509A (en) * | 1958-09-26 | 1961-02-14 | Cohen Milton Joseph | Disposable hypodermic syringe |
| US3005300A (en) * | 1959-09-08 | 1961-10-24 | Walter A Shields | Apparatus for positioning closure caps on vials |
| FR1365605A (fr) * | 1963-06-21 | 1964-07-03 | Strunck & Co Maschf H | Procédé et dispositif pour le nettoyage et la stérilisation des bouteilles, ampoules et autres récipients |
| FR1431184A (fr) * | 1965-02-27 | 1966-03-11 | Valve simplifiée pour récipient aérosol | |
| US3378008A (en) * | 1965-07-23 | 1968-04-16 | Min I Jet Corp | Hypodermic syringe with vial |
| US3538672A (en) * | 1968-07-16 | 1970-11-10 | Walter A Shields | Apparatus for delivering closure caps to vials |
| JPH024332B2 (https=) * | 1980-09-01 | 1990-01-26 | Emu Ai Wai Hoomushisutemuzu Ltd |
-
1985
- 1985-05-14 JP JP60502069A patent/JPS61502099A/ja active Pending
- 1985-05-14 DE DE8585901962T patent/DE3579893D1/de not_active Expired - Fee Related
- 1985-05-14 EP EP85901962A patent/EP0185027B1/fr not_active Expired - Lifetime
- 1985-05-14 WO PCT/CH1985/000080 patent/WO1985005269A1/fr not_active Ceased
- 1985-05-15 US US06/833,392 patent/US4703781A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3579893D1 (de) | 1990-10-31 |
| WO1985005269A1 (fr) | 1985-12-05 |
| EP0185027A1 (https=) | 1986-06-25 |
| US4703781A (en) | 1987-11-03 |
| EP0185027B1 (fr) | 1990-09-26 |
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