JPS6126773B2 - - Google Patents

Info

Publication number
JPS6126773B2
JPS6126773B2 JP52128565A JP12856577A JPS6126773B2 JP S6126773 B2 JPS6126773 B2 JP S6126773B2 JP 52128565 A JP52128565 A JP 52128565A JP 12856577 A JP12856577 A JP 12856577A JP S6126773 B2 JPS6126773 B2 JP S6126773B2
Authority
JP
Japan
Prior art keywords
bicyclo
benzo
chloro
formula
exo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52128565A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5368767A (en
Inventor
Samyueru Saueiji Deiuido
Surei Toomasu
Kerotsuku Kuraaku Jon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of JPS5368767A publication Critical patent/JPS5368767A/ja
Publication of JPS6126773B2 publication Critical patent/JPS6126773B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP12856577A 1976-10-27 1977-10-26 Biologically active tricyclic compound process for preparing same and medical composition containing same Granted JPS5368767A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB44675/76A GB1570613A (en) 1976-10-27 1976-10-27 Biologically active tricyclic compounds and pharmaceutical compositions containing same

Publications (2)

Publication Number Publication Date
JPS5368767A JPS5368767A (en) 1978-06-19
JPS6126773B2 true JPS6126773B2 (OSRAM) 1986-06-21

Family

ID=10434306

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12856577A Granted JPS5368767A (en) 1976-10-27 1977-10-26 Biologically active tricyclic compound process for preparing same and medical composition containing same

Country Status (17)

Country Link
US (1) US4801753A (OSRAM)
JP (1) JPS5368767A (OSRAM)
AU (1) AU513607B2 (OSRAM)
BE (1) BE860141A (OSRAM)
CA (1) CA1081704A (OSRAM)
DE (1) DE2747987A1 (OSRAM)
DK (1) DK147280C (OSRAM)
ES (1) ES463570A1 (OSRAM)
FI (1) FI64574C (OSRAM)
FR (1) FR2369245A1 (OSRAM)
GB (1) GB1570613A (OSRAM)
HU (1) HU178984B (OSRAM)
IE (1) IE45889B1 (OSRAM)
LU (1) LU78392A1 (OSRAM)
NL (1) NL7711777A (OSRAM)
SE (1) SE425779B (OSRAM)
ZA (1) ZA776142B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
US5089506A (en) * 1990-04-30 1992-02-18 G. D. Searle & Co. Ethanobicyclic amine derivatives for cns disorders
US5215992A (en) * 1990-04-30 1993-06-01 G. D. Searle & Co. Ethanobicyclic amine derivatives for CNS disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159677A (en) * 1960-04-12 1964-12-01 Parke Davis & Co Fluorenamines and process for preparation thereof
US3836670A (en) * 1971-11-19 1974-09-17 American Home Prod Benzobicycloalkane amines for inducing analgesia
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US4313896A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Aryloxyphenylpropylamines
GB1504694A (en) * 1974-04-08 1978-03-22 Akzo Nv Benzo-bicyclononene derivatives
GB1549172A (en) * 1975-04-29 1979-08-01 Akzonv Benzobicyclononene derivatives

Also Published As

Publication number Publication date
JPS5368767A (en) 1978-06-19
FR2369245B1 (OSRAM) 1980-09-26
SE7712040L (sv) 1978-04-28
IE45889B1 (en) 1982-12-29
DK147280B (da) 1984-06-04
DK147280C (da) 1984-12-03
FR2369245A1 (fr) 1978-05-26
FI64574B (fi) 1983-08-31
FI64574C (fi) 1983-12-12
ES463570A1 (es) 1979-09-16
NL7711777A (nl) 1978-05-02
US4801753A (en) 1989-01-31
DK474977A (da) 1978-04-28
AU2998377A (en) 1979-05-03
CA1081704A (en) 1980-07-15
SE425779B (sv) 1982-11-08
FI773193A7 (fi) 1978-04-28
LU78392A1 (OSRAM) 1978-01-26
DE2747987C2 (OSRAM) 1988-02-25
ZA776142B (en) 1978-06-28
DE2747987A1 (de) 1978-05-03
GB1570613A (en) 1980-07-02
IE45889L (en) 1978-04-27
HU178984B (en) 1982-07-28
BE860141A (fr) 1978-04-26
AU513607B2 (en) 1980-12-11

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