JPS6111137A - Water in oil type emulsion composition - Google Patents

Abstract

PURPOSE:To obtain a stable water in oil type emulsion composition by mixing 1-50wt% specified gelled component, 30-80wt% oil phase component, 5-70 wt% aq. phase component, with aq. soln. of polysaccharide and monosaccharide. CONSTITUTION:Aq. soln. contg. >=0.1wt% at least one selected from fulfuric acid salt of poly- or mono-saccharide, at least one liquid or paste substance at ordinary temp. selected from partial ester of polyhydric alcohol having >=3 OH groups with fatty acid, and 1-10mol EO adduct of hydroxy fatty acid triglyceride, are mixed to prepare a gelled compsn. 1-50wt% said gelled compsn., 30- 80wt% oil phase component, and 5-70wt% aq. phase component are mixed to prepare a water in oil type emulsion compsn.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention provides a stable water-in-oil emulsion containing a gel-like silk composition containing polysaccharide or monosaccharide sulfate, which has excellent effects on the skin. Regarding the composition.

[Prior art and problems to be solved by the invention] Conventionally, as a method for obtaining a water-in-oil emulsion composition, a water phase component is added to an oil phase component containing a surfactant, and the mixture is stirred. However, it was not possible to obtain a product with good stability due to separation and aggregation over time.As a method to improve this drawback, a method using a gel (Japanese Patent Publication No. 48-15798, Japanese Patent Publication No. 15798-1987, 21393
(Japanese Patent Publication No. 56-53608) are also disclosed, but in order to obtain a truly stable composition, there are limitations in the formulation such as a limited amount of water, and oils depending on the use are It took half an eye to obtain a water-in-water type emulsion composition. As a result of extensive research to improve the above drawbacks, the present inventors have developed an aqueous sulfate solution of polysaccharide or monosaccharide that has excellent effects on the skin. The inventors discovered that a stable gel could be formed from a specific surfactant and completed the present invention in a patent application filed in 1983.

[Means for solving problems]

That is, the present invention provides an aqueous solution (A) containing 0.1% by weight or more of one or more substances selected from the group consisting of polysaccharides and monosaccharide sulfates, and a polysaccharide having three or more hydroxyl groups in the molecule. Partial ester of alcohol and fatty acid, and ethylene oxide of hydroxy fatty acid triglyceride 1~
] A gel-like composition consisting of 1 to 50% by weight (hereinafter simply referred to as %) of one or more substances selected from the group consisting of 0 molar adducts that exhibit a liquid or pasty state at room temperature and an oil. This is a water-in-oil emulsion composition characterized by blending 30 to 80 io of a phase component and 5 to 70% of an aqueous phase component.

Next, the configuration of the present invention will be described.

Sulfates of polysaccharides or monosaccharides used in the present invention include sodium salts of mucopolysaccharides such as chondroitin sulfate, keratosulfate, dermatan sulfate, polysaccharide sulfates such as dextran sulfate, maltitol sulfate, and monosaccharide sulfates such as sorbitol sulfate,
Inorganic and organic salts such as potassium salts, triethanolamine salts and amino acid salts such as arginine, preferably sodium and potassium salts.

The above-mentioned sulfate is blended into the gel composition constituting the water-in-oil emulsion composition of the present invention as an aqueous solution having a concentration of 0.1% by weight (hereinafter simply referred to as %) or more.

(Left below) The partial ester of polyhydric alcohol and fatty acid used in the present invention can be derived from the following substances. The polyhydric alcohols used have three or more hydroxyl groups, such as glycerin, diglycerin, triglycerin, tetraglycerin, pentaglycerin, hexaglycerin, heptaglycerin, octaglycerin, nonaglycerin, decaglycerin, undecaglycerin, and dodecaglycerin. , tridecaglycerin, tetradecaglycerin, pentadecaglycerin, hexadecaglycerin, octadecaglycerin, trimethylolethane, trimethylolpropane, pentaerythritol, sorbitan/sorbitol, and the like. The fatty acids that are reacted with these polyhydric alcohols to form partial esters are selected from caprylic acid, capric acid, monooleic acid, linoleic acid, ricinoleic acid, isooctanoic acid, isohexdecanoic acid, inoctadecanoic acid, etc. . These partial esters generally refer to monoesters, diesters, triesters, tetraesters, pentaesters, etc., or mixtures thereof. In this case, the mixing ratio varies depending on the type of carboxylic acid and the number of hydroxyl groups in the polyhydric alcohol.

Examples of the ethylene oxide adduct of hydroxy fatty acid triglyceride used in the present invention include castor oil or hydrogenated castor oil to which 1 to 10 moles of ethylene oxide are added, and mixtures thereof are preferred.

The substances that form a gel composition with an aqueous sulfate solution of polysaccharides or monosaccharides include partial esters of polyhydric alcohols having at least three or more hydroxyl groups and ethylene oxide adducts of hydroxy fatty acid triglycerides. Select from liquid or paste at room temperature.

(aqueous solution containing 0.1% by weight or more), a partial ester of a polyhydric alcohol having 3 or more hydroxyl groups in the molecule and a fatty acid, and an adduct of 1 to 10 moles of ethylene oxide of hydroxy fatty acid triglyceride. In carrying out the present invention, one or more substances (B) that are liquid or paste-like at room temperature should be added to the above-mentioned gel-like composition in the target water-in-oil emulsion composition in terms of weight ratio. 1 to 50% by weight of the compound is blended.

The oils used in the present invention include waxes such as ceresin, peace wax, carnauba wax, and solid paraffin;
Liquid paraffin, squalane, petrolatum, glyceryl
Oils commonly used in cosmetics and pharmaceuticals are used, such as ester oils such as tri-2-ethylhexinoate and liquid or semi-solid oils such as silicone. The blending amount is generally about 30 to 80%.

In the present invention, water is blended in an amount of about 5 to 70%.

In carrying out the present invention, in addition to the above-mentioned essential ingredients, drugs such as vitamins, antioxidants, preservatives, pigments, fragrances, powders such as talc and mica, moisturizing agents such as glycerin/maltitol and hyaluronic acid, and Additives commonly used in cosmetics and pharmaceuticals, such as sticky agents and chelating agents, can be incorporated within the range that does not impair the effects of the present invention.

〔Effect of the invention〕

It is known that the polysaccharide sulfates used in the present invention, such as the sodium salts of chondroitin 4-sulfate and chondroitin-6 sulfate, are present in the human dermis and are closely related to the water retention and elasticity of skin tissue. There is also an example (Japanese Patent Publication No. 32-2700) in which it has been incorporated into cosmetics for the purpose of preventing skin aging, protecting and beautifying the skin. In addition, for example, dextran sulfate is known to activate blood circulation and improve metabolism (Japanese Patent Publication No. 39-2a47).
. Furthermore, the monosaccharide sulfate used in the present invention, such as sorbitol sulfate, is expected to have anti-aging effects on the skin.

Therefore, the water-in-oil emulsion composition of the present invention, which is made by blending a gel composition using an aqueous sulfate solution of a polysaccharide or monosaccharide with such excellent effects, oil and water, has excellent properties as described below. Furthermore, the formulation can be configured within a wide range, making it extremely useful.

The present invention will be explained in detail below with reference to Examples and Comparative Examples, but the present invention is not limited thereto. The blending amount is in weight%.

(Left below) Prescription example I L Squalane 25
%2 selenium
33. Peace wax
14 Vaseline
55 Glycerol monooleate
26 Diglycerol diisostearate
27. Sodium fundroitin sulfate
2a Ion exchange water
559 Dipropylene glycol
3ml, 3-butylene gelicol
2 Conventional Manufacturing Method Notification 1.2.3.45 and 6 were heated and dissolved in the oil phase at 70°C.
After adding and 10 (aqueous phase), emulsification and dispersion treatment was performed using a homomixer, and the mixture was cooled to room temperature to obtain a water-in-oil emulsion composition.

Part of method A8 for producing a water-in-oil emulsion composition of the present invention (
A gel-like composition is obtained by adding an aqueous solution in which Condition 7 is dissolved in 14%) to the mixed solution of the plate 5.6 with stirring. Separately 44
; 1.2.3 and 4 are heated and dissolved at 70°C, and the above-mentioned gel composition is added therein and stirred and dispersed. Further A
An aqueous solution obtained by dissolving &9 and 10 in No. 8 (41%) was heated to 70° C., added, emulsified and dispersed in a homomixer, and cooled to room temperature to obtain an emulsified composition.

Test item (1): Values measured using a hard 11 card tension meter. Storage conditions are room temperature.

30 Stability Approximately 1 cm wide and 5 cm deep on the surface of the cream
I made 4 parts of a &c. and stored them at 30"C, and those with a certain degree of oiliness are marked with an x. (Hereinafter the margin) (Hereinafter the margin) Water 21B Hydrogenated castor oil E-
05 molar adduct 6C ceresin
2 Beeswa, Kusu
1 Vaseline
7 Liquid paraffin 5D Ion-exchanged water 55 Water-soluble drug 5 Add phase A to phase B to make a gel-like composition, add to phase C dissolved at 70°C, and stir and disperse.

Further, Phase D, which had been humidified at 70°C, was added, emulsified and dispersed with stirring, and then cooled to room temperature.

(Margin below) Example 2 W10 cream %A
Sodium Sorbitol Sulfate 1 Sodium Chondroitin Sulfate 1 Noum 1 Ion Exchange Water
14B Glycerol monooleate 2Diglycerol diisostearate 2C Ceresin
2 piece wax 1 Microcrystalline wax 2 Vaseline
8 Squalane
15,,,,,a
Appropriate amount of pigments and fragrances
Appropriate amount p ion exchange water 48
Dipropylene glycol 21-3 Butylene glycol 1 Hyaluronic acid
1 preservative
Appropriate amount Example 3 W10 emulsion
%A Sodium chondroitin sulfate
2 Sodium dextran sulfate 1 Ion exchange water 13B Triglycerol diisostearate 5C Liquid paraffin
1゜Squalane
10 Vaseline
5 behenyl alcohol 1
Vitamins Appropriate amount Colors Fragrance D Ion exchange water 42 Dipropylene glycol 2 Glycerin
2 polyethylene glycol
2 Hyaluronic acid
Sodium 2-pyrrolidone carboxylate 2L-
Monosodium glutamate 1 preservative
Appropriate amount of chelating agent
Appropriate amount of inorganic powder pigment (blank below) Example 4 W10 Sunscreen Cream Foundation A Sodium chondroitin sulfate 2% ion exchange water 14B diglycerol diisostearate 4 Sorbitan monooleate 107 Lecine
2 Beeswa, Kusu
1 Microcrystalline wax
2 Squalane 15 Ultraviolet absorber Appropriate amount of titanium dioxide
]0 inorganic pigment powder
2 fragrance
Appropriate amount of D ion exchange water
39 dipropylene glycol 31-3 butylene gelicol
3 Maltitol 1 Glycerin 1 Preservative
Appropriate amount Examples 2 to 4 were manufactured according to the manufacturing method of Example 1, and products with good stability and usability were obtained.

Patent Applicant Shiseido Co., Ltd. Voluntary amendment to the procedure) August 10, 1982 1. Indication of the case Patent Application No. 131789 of 1987 2. Name of the invention Water-in-oil emulsion composition 3. Person making the amendment Relationship to the case Patent applicant 4, Detailed description of the invention column 5 of the specification subject to amendment, Contents of amendment + 11 The statement “Tokukosho” on page 2, line 9 of the specification,
Correct it to "Tokkai Sho."

30 The 9th line of the 11th summer of the specification “room temperature” is [
0℃, room temperature, 37℃".

30 The statement “30℃” on page 11, line 12 of the specification will be corrected to “0℃, room temperature, 37℃”.

that's all

Claims (1)

[Claims] (1) 1 selected from the group consisting of sulfates of polysaccharides and monosaccharides
Partial ester of an aqueous solution (A) containing 0.1% by weight or more of a species or two or more substances, a polyhydric alcohol having three or more hydroxyl groups in the molecule, and a fatty acid, and ethylene oxide of hydroxy fatty acid triglyceride 1- Gel-like compositions 1 to 1 comprising one or more substances (B) that are liquid at room temperature and selected from the group consisting of 10 molar adducts.
50% by weight, oily component 30~80% by weight, and water phase component 5~
70% by weight of a water-in-oil emulsion composition.