JPS6075410A - Dentifrice - Google Patents

Abstract

PURPOSE:To provide a dentifrice resistant to the dissipation of moisture, free from the changes such as weight loss, surface roughening, etc., and giving excellent feeling to the palate, by filling a dentifrice composition compounded with a humectant containing a specific amount of glycerol in a container having a body made of a plastic having a specific moisture permeability. CONSTITUTION:The objective dentifrice is obtained by filling (A) a dentifrice composition produced by mixing a dentifrice with 30-70wt% (based on the composition) of a humectant containing 20-60wt%, especially 25-50wt% (based on the composition) of glycerol, in (B) a plastic container having the body part formed to have a moisture permeability of >=5g/m<2>-day-50mu [especially >=10g/ m<2>]. Preferably, the body part is formed to have an oxygen permeability of >=50cc/100inch<2>-mil-day-atm(25 deg.C), and preferably, the body part is made of a polyolefin and the head is made of polyester or polyamide. EFFECT:There is no honeycomb surface roughening and consistency change, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a toothpaste filled in a container having a plastic container body body having a moisture permeability of 51/day/50μ or more. To provide a toothpaste that does not cause weight loss, roughened skin, change in consistency, etc. due to volatilization of water even when filled in a plastic container with high water content, and has a good feeling of use.

In the past, various materials have been proposed for toothpaste containers, but among these, glass containers are superior in that they have extremely low air, oxygen and moisture permeability, and are also able to see through the contents. However, it has problems in terms of cost, weight, etc., and has the fatal drawback of being extremely vulnerable to physical shock. In addition, metal containers such as metal tubes have extremely low air, oxygen, and moisture permeability, making them excellent for preserving toothpaste, but it is said that trace amounts of metals may leach into the composition and cause corrosion of the container. I have a problem.

On the other hand, plastic containers such as plastic tubes and plastic/metal foil laminate tubes do not have the drawbacks of glass containers and metal containers and are superior, but plastic containers that do not have a metal foil layer In the case of containers, the oxygen permeability is high, and this waste oxygen passes through, causing problems such as oxidation of flavoring agents in toothpaste. Therefore, metal foil laminated tubes have traditionally been widely used as plastic containers, but recently dis-inser containers, VO
It has become desirable to use containers made entirely of plastic in the form of ME containers, aerosol containers, etc. as containers for toothpaste compositions.

In this case, for plastic containers that do not have a metal foil layer, it is effective to use a plastic layer that has a low oxygen permeability as the single layer of plastic that makes up the container, but in many cases, lowering the oxygen permeability Moisture permeability increases (moisture permeability becomes 52/n?・day・50μ or more), and when toothpaste is filled in a plastic container with such a high moisture permeability, the water in the toothpaste evaporates. The amount of toothpaste used decreased, and the skin became rougher with honeycomb-like air bubbles appearing in the area that came in contact with the plastic toothpaste container (honeycomb-like skin roughness), and the consistency of the toothpaste changed and its extrusion properties became worse. I have something to do. To solve this problem, it has been proposed in the past to form containers using a laminated material made by laminating plastics with low oxygen permeability and plastics with low moisture permeability. Improvements to the container surface have been used to prevent moisture from evaporating, but this is not always sufficient to reliably prevent moisture from permeating, and the laminated materials described above are difficult to form into containers and are expensive. There is a problem that

Therefore, there is a need for improvements in the composition itself in order to prevent water volatilization from dentifrice compositions filled in plastic containers with high moisture permeability.

In view of the above circumstances, the present inventors used a plastic container with high moisture permeability, and found that when this type of container is filled, almost no moisture evaporates, resulting in honeycomb-like skin roughness and consistency. As a result of various studies on dentifrice compositions that do not undergo changes, we found that glycerin was added to the dentifrice composition by 20 to 60% of the total composition (wt%).
, hereinafter the same) containing 30 to 70% of the total composition.
By blending H, a dentifrice composition with extremely low moisture volatilization can be obtained, and this dentifrice composition can be filled into a plastic container with a high moisture permeability without any problem,
The inventors have discovered that the above object can be effectively achieved and have come up with the present invention.That is, according to the studies of the present inventors, the water permeability is 59/r.
r?・If a conventional toothpaste composition is filled in a plastic container with a high moisture permeability of 50μ, the water in the composition will evaporate, resulting in weight loss, honeycomb-like skin roughness, changes in consistency, etc. However, a toothpaste composition containing a moisturizing agent containing 20 to 60% of the total composition of glycerin in an amount of 30 to 70% of the total composition is filled into a plastic container with a high moisture permeability as described above. However, the water content in the composition hardly evaporates, resulting in disadvantages such as weight loss of the composition, rough skin, and changes in consistency, which is a new finding of the present inventors. be.

It has also been proposed to prevent the volatilization of water in the toothpaste composition by adding a water-soluble polymeric substance such as vinylpyrrolidone to the toothpaste composition. According to the authors, this method causes stringiness in the dentifrice composition, poor kneading, and problems with filling and usability during the manufacturing process.

The present invention will be explained in more detail below.

The toothpaste according to the present invention has a moisturizing agent content of 30% of the total composition.
A dentifrice composition in which the moisturizing agent has a glycerin content of 20 to 60% by weight based on the entire composition has a moisture permeability of 51% in the body of the plastic container body. /d・day・50μ or more.

In this case, the shape of the container filled with the dentifrice composition of the present invention is not particularly limited, and may be formed into a tube shape, a bottle shape, a dispenser container, a VOME container, an aerosol container, and the like. In this case, these containers are
As shown in FIGS. 2 to 2, the container body 3 includes a body 1 and a head or mouth portion 2. In the container used in the present invention, at least the body 1 is provided.
A plastic container body made of plastic is used. Of course, the container body 3
A device whose entire body (body 1 and head or mouth portion 2) is made of plastic can also be effectively used.

Here, examples of the plastic forming the body (and head or mouth) of the plastic container body include low density polyethylene, high density polyethylene, polystyrene, polyvinyl chloride, vinyl oxide, polypropylene, and polyethylene terephthalate. Corner polyester, polyvinylidene chloride, polycarbonate, polyacetal, polyamide, cellulose resin, rubber, ethylene/vinyl acetate copolymer, ethylene/acrylic acid copolymer, ethylene/methacrylic acid copolymer, ethylene/acrylic acid copolymer Polymers, ethylene/methacrylic acid copolymers, etc. are mentioned, and it is preferable to use these as a single layer, but in some cases, it can also be constructed as a υ multilayer by methods such as multilayer blowing or lamination. Also, in this case, what about the body of the container? It is preferred that the lyolefin, head or mouth portion be formed of polyester or polyamide.

Further, as for the container used in the present invention, at least the body thereof has a moisture permeability of 5 f/n? - Those formed with a da of 7.50μ or more are used. Of course, in addition to this, the head or mouth area has a moisture permeability of 52/ze・da.
Those formed with a thickness of y·50μ or more can also be effectively used. According to the present invention, as will be described later, the amount of the humectant added is 30 to 70% by weight of the entire composition, and the amount of glycerin in the moisturizer is 20 to 70% by weight based on the entire composition.
By filling the dentifrice composition with a weight ratio of ~60%, the weight of normal dentifrice compositions is reduced due to evaporation of water.
A plastic container with a moisture permeability of 52/-・da7・50μ or more can be used, which may cause problems such as honeycomb-like skin roughness and changes in consistency, and especially moisture that cannot be used in ordinary toothpaste compositions. Transmittance 10r/m'-
day-50/l! The above plastic containers can also be suitably used. In addition, even if a plastic material with a water permeability of 10 r/m'/day/50 μ or more is used for the head or mouth of the container, drying at the head or mouth and a decrease in extrudability due to drying can be prevented.
Containers of this type can be used without any problems.

In the present invention, the moisture permeability of the plastic container is as described above, but the oxygen permeability is as per ASTM D.
When measured according to the measurement method of No. 1434, at least the torso, preferably the torso and the head or mouth part is 50%
Department / 1001nch' ・mil・day ・atm
(25℃), especially 150-250cc/100
1nch9@ml·da3zatm (25°C) is preferable.

Furthermore, although the plastic container can be formed into various shapes as mentioned above, the dentifrice composition of the present invention has extremely low moisture volatilization, so it can be used in dispenser containers, VOME containers, aerosol containers, etc. A plastic container as shown in FIG. 2 having a body 1 of a container body 3 and a head or mouth portion 2 separated by a partition 4 can be effectively used. That is, in a container having such a head or mouth part, the toothpaste composition accumulated in the head or mouth part may dry and the toothpaste may not come out of the container, so an overcap or the like is usually used. I put it on to prevent it from drying out, but it doesn't prevent it enough. On the other hand, even when such a container is filled with the dentifrice composition of the present invention, it is possible to prevent the above-mentioned problem of the dentifrice drying on the head or around the mouth and not coming out of the container.

Here, to give an example of such a container,
4641, Utility Model 55-38783, Utility Model 56-46
572% commercial production 1986-100378, commercial production 1986-12
1677, Utility Model 57-44041, Utility Model 57-74
168, U.S. Pat. No. 57-164079, JP-A No. 57-68
Examples include those described in No. 367, JP-A No. 57-68368, etc., and the tooth swelling material of the present invention can be suitably used by filling these containers.

In the present invention, the dentifrice composition filled in the container has a moisturizing agent content of 30 to 70% by weight based on the total composition, and an amount of glycerin in the moisturizing agent is 2% by weight based on the total composition.
It is 0 to 60 fftit%.

Here, as a humectant, glycerin is added to 20% of the total toothpaste composition.
It is necessary to contain ~60%; if it is less than 20%, the water in the composition evaporates and the weight decreases, resulting in rough bee-like skin and dryness on the head or mouth area, and if it is more than 60%. The usability becomes worse. In addition, in the above-mentioned humectant, the content of glycerin in the entire composition is more preferably 25 to 50q6. In addition, other ingredients of the above moisturizer include sorbitol, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, chilipropylene glycol, xylit,
Appropriate substances such as marnut and luffitite may be used, and these ingredients and glycerine may be used in combination as necessary.

In addition, the amount of the moisturizing agent added is 30 to 30% of the total toothpaste composition.
It is necessary to make it 70chi, a little more than 30q6 and n1
Moisture in the composition evaporates and the weight decreases, and if the composition has honeycomb-like rough skin and dryness with elms on the head or mouth, the feel of the composition will be poor if it exceeds 1-1% or 70%.

The preferred composition of the moisturizing agent is 35-60% of the total composition.

As other components of the dentifrice composition of the present invention, appropriate components depending on the type of dentifrice composition are used. For example, if necessary, silica-based abrasives such as dibasic calcium phosphate dihydrate and anhydride, dibasic calcium phosphate, dibasic calcium phosphate, calcium carbonate, calcium pyrophosphate, calcium sulfate, aluminum hydroxide, alumina, precipitated silica, Aluminum silicate, insoluble sodium metaphosphate, tertiary magnesium phosphate, magnesium carbonate, bentonite, zirconium silicate, abrasives such as synthetic resins (compounding amount usually 10-50%), caradanan, sodium Calgaxymethylcellulose, methyl 2 Cellulose derivatives such as cellulose, hydroxyethyl cellulose, sodium carboxymethyl hydroxyethyl cellulose, and cellulose sulfate, alkali metal alginates such as sodium alginate, propylene glycol alginate ester, gums such as xanthan gum, locust bean gum, tragacanth gum, karaya gum, and gum arabic. Binder such as polyvinyl alcohol, alkali metal salt of polyacrylic acid, synthetic binder such as carboxyvinyl polymer, inorganic binder such as montmorillonite, vegum, laponite (compounding amount usually 0.5 to 5
h), water-soluble salts of higher alkyl sulfates whose alkyl group has 8 to 18 carbon atoms, such as sodium lauryl sulfate and sodium myristyl sulfate; water-soluble higher fatty acid monoglycerides, such as hydrogenated coconut oil fatty acid monoglyceride monosodium sulfate; Sulfate, alkylaryl sulfonate such as sodium dodecylbenzene sulfonate, higher alkyl sulfonate, sodium α-olefin sulfonate, higher fatty acid ester of 1,2-dihydroxyderonosulfonate, N-lauroyl, N -lower aliphatic aminocarboxylate such as sodium, potassium or ethanolamine salts of myristoyl or N-balmitoylsarcosine -? Anion activators such as substantially saturated higher aliphatic acylamides of phosphoric acid compounds, sucrose fatty acid esters in which the fatty acid group has 12 to 18 carbon atoms, such as lauric acid soethanolamide, sucrose mono- and dulaurate, and lactose fatty acids. ester, lactitol fatty acid ester, maltitol fatty acid ester, stearic acid monoglyceride, polyoxyethylene sorbitan monolaurate, polyoxyethylene hydrogenated castor oil, sorbitan monostearate condensate with about 60 moles of ethylene dalicol added, ethylene oxide and propylene Surfactants such as nonionic surfactants such as oxide polymers and derivatives such as polyoxyethylene polyoxyderopyrene monolauryl ester, and amphoteric surfactants such as betaine type and amino acid type (
(usually 0 to 7q6, especially 0.5 to 5%), and menthol, carvone, anethole, eugenol, methyl salicylate, spearmint oil, peno-R-mint oil, lemon oil, orange oil, seso oil, rose. Fragrances and flavors such as mari oil, cinnamon oil, viment oil, cinnamon leaf oil, perilla oil, wintergreen oil, clove oil, eucalyptus oil, strawberry flavor, orange flavor, lemon flavor, apple flavor, banana flavor, pineapple flavor, etc. Sweeteners such as zatukarin sodium, stevioside, neohess nami dihydrochalcone, glycyrrhizin, perilartin, p-methoxycinnami "tuqualdehyde," gelatin, ibutone, arginine hydrochloride, albumin, casein, titanium dioxide, pigments, preservatives It can be produced by mixing the above-mentioned desired components with an appropriate amount of water and according to a conventional method.

In addition, the dentifrice composition of the present invention includes degistranase, amylase, protease, mutanase,
Enzymes such as phosphatase, lysozyme, and Litetsuenzyme, alkali metal monofluorophosphates such as sodium monofluorophosphate and potassium monofluorophosphate, fluorine compounds such as sodium fluoride and stannous fluoride, monofluorophosphate, etc.
Stannous compounds such as tin, chlorhexidine hydrochloride, chlorhexidines such as chlorhexisone gluconate, sodium copper chlorophyllin, hinokitiol, epsilon aminocaproic acid, tranexamic acid, ethanedihydroxydiphosphonate, allantoin, hyaluronic acid ,
Herbal medicines such as dihydrocholesterol, glycyrrhetinic acid, azulene, and chamomile, chelating phosphoric acid compounds such as chlorophyll and dalicerophosphate, and water-soluble inorganic phosphoric acid compounds, etc.
A species or two or more species may be blended.

Next, examples and comparative examples will be shown to specifically explain the present invention.

[Examples 1 to 6, Comparative Examples 1 to 3] Toothpastes of Examples 1 to 6 and Comparative Examples 1 to 3 having the compositions shown in the table below were prepared by a conventional method. Next, brush your teeth with each line.
Store it in a dispenser container as described in Publication No. 7-44041 (Fig. 2), and then check the degree of toothpaste loss, degree of dryness on the head or mouth area, and degree of honeycomb-like skin roughness in 6 by the following method. I looked it up. In addition, the feeling of use of each toothpaste was examined using the following method. The results are also listed in the table. The container used has a body made of polypropylene and a moisture permeability of 1.21i'/n?・
day 650μ, oxygen permeability 180cc/1nc
h'・mil・day-atm (25℃) The head or mouth is made of polyethylene terephthalate and has a moisture permeability of 48? / t day 50μ.

(11) Method for Measuring the Degree of Weight Loss Each line of toothpaste was filled into the above container and stored at 40°C for 3 months, after which the level of weight loss of each line of toothpaste was examined.

Evaluation criteria: ○: Decrease - Appetizers are 2 times less △: 〃 2 to 5 times ×: 〃 5 times more (2) Measurement method for the degree of dryness at the head or mouth area Fill each part so that the toothpaste is present up to the exit part of the mouth or mouth part, and heat it at 30°C.
The degree of dryness of each toothpaste after being stored for 3 days was examined.

Evaluation Criteria 1: The toothpaste is dry and does not come out from the outlet even when pressed on the mouth area.

2: When the toothpaste dries and you press the area around your mouth, a small amount of toothpaste comes out from the outlet.

3: The toothpaste is a little dry, but there are no problems when using it.

4: The toothpaste hardly dries and there is no problem in use.

5: The toothpaste does not dry out and there is no problem in using it.

(3) Degree of honeycomb-like skin roughness Each line toothpaste was filled into the above container and stored at 40° C. for 3 months, after which the degree of honeycomb-like roughness on the skin was examined.

Evaluation criteria 1: Honeybee-like rough skin was observed on the toothpaste as a whole.

2: Bee fruit-like rough skin was observed partially on the toothpaste.

3: Honeycomb-like rough skin was observed scattered on the toothpaste,
I wish the product value had been lost.

4: The toothpaste had slight nest-like rough skin spots.

5: No honeycomb-like rough skin was observed in the toothpaste.

(4) Feeling of use A control toothpaste with the following composition was prepared, and this control toothpaste 1.5
Panelists were asked to use each of the toothpastes 1.57 and 1.57 in the Examples and Comparative Examples, respectively, and the sensory evaluation was conducted to determine whether the toothpastes in the Examples and Comparative Examples had a better feeling in use than the control toothpastes.

Control toothpaste composition Propylene glycol 2.5 Sodium carboxymethyl cellulose 0.9 Carayenan 0.2 9 Glycerin 11.1 Vusorvit (70% aqueous solution) 6.9 P Precipitated silica 2.5 Satucalin sodium o, 18 Fragrance 1.1 Dibasic calcium phosphate 48.0 1/Sodium lauryl sulfate 1.5 Purified water 25.12 // Evaluation criteria ○: Feeling of use is equivalent to the control toothpaste based on overall preference.

△: The feeling of use is inferior to the control toothpaste in terms of overall preference, but it can be used.

×: Feeling of use is inferior to the control toothpaste based on overall preference.

(5) Comprehensive evaluation Each line of toothpaste was comprehensively evaluated on the items (1) to (4) above.

0 Evaluation Criteria ○: No problems in all items (1) to (4).

Δ: Even if it is inferior in any of the items (1) to (4), it is within the usable range.

X: Inferior in any of the items m to (4) and causing problems in use.

The results in the table show that even when the toothpastes d of Examples 1 to 6 are filled into plastic containers with high moisture permeability, volatilization of water is extremely low, the toothpaste is hardly placed on the head or mouth, and It was observed that the degree of dryness in the areas was small, the degree of nest-like roughness on the skin was small, and the feeling of use was good. In contrast, glycerin accounts for 10% of total toothpaste.
The rice bran toothpaste of Comparative Example 1, which contained 20.5% of the moisturizing agent, 15% of the total glycerin, and 39% of the total moisturizing agent.
．． In the toothpaste of Comparative Example 2 containing 5% glycerin, water evaporates, resulting in loss of toothpaste, dryness on the head or around the mouth, and honeycomb-like roughness. The toothpaste of Example 3 had a poor feel.

[Brief explanation of drawings]

FIGS. 1 and 2 are cross-sectional views each showing an example of a container filled with the dentifrice composition of the present invention. 1... Torso, 2... Head or mouth, 3...
Container body. 23 - Kinuichi Figure 1

Claims (1)

[Claims] 1. The amount of humectant added is 30 to 70 weight Jt% of the entire composition.
A dentifrice composition in which the amount of glycerin in the moisturizer is 20 to 60 weight 11 with respect to the entire composition has a water permeability of 51/r at least in the body of the plastic container body.
r? A toothpaste characterized by being filled into a container having a diameter of 50 μm or more. 2. The body of the plastic container has an oxygen permeability of 50cc/10ml.
The toothpaste according to claim 1, which is formed at a temperature of 25° C. or higher. 3. Is the body of the plastic container body made of polyolefin and the head made of polyester or polyester? The toothpaste according to claim 1 or 2, which is made of lyamide.