JPS6027676B2 - ピリミジノアミノメチルエルゴリン誘導体の製法 - Google Patents

ピリミジノアミノメチルエルゴリン誘導体の製法

Info

Publication number
JPS6027676B2
JPS6027676B2 JP49144603A JP14460374A JPS6027676B2 JP S6027676 B2 JPS6027676 B2 JP S6027676B2 JP 49144603 A JP49144603 A JP 49144603A JP 14460374 A JP14460374 A JP 14460374A JP S6027676 B2 JPS6027676 B2 JP S6027676B2
Authority
JP
Japan
Prior art keywords
dimethyl
formula
carbon atoms
group
pyrimidinoaminomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49144603A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5095299A (en, 2012
Inventor
アルカリ ジユリアナ
ベルナルデイ ルイジ
ボシシオ ジエルマノ
グレ−セル アルフレド
テムペリリ アルデミオ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of JPS5095299A publication Critical patent/JPS5095299A/ja
Publication of JPS6027676B2 publication Critical patent/JPS6027676B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Coloring (AREA)
JP49144603A 1973-12-21 1974-12-18 ピリミジノアミノメチルエルゴリン誘導体の製法 Expired JPS6027676B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT5453373 1973-12-21
IT54533/73 1973-12-21

Publications (2)

Publication Number Publication Date
JPS5095299A JPS5095299A (en, 2012) 1975-07-29
JPS6027676B2 true JPS6027676B2 (ja) 1985-06-29

Family

ID=11287369

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49144603A Expired JPS6027676B2 (ja) 1973-12-21 1974-12-18 ピリミジノアミノメチルエルゴリン誘導体の製法

Country Status (15)

Country Link
JP (1) JPS6027676B2 (en, 2012)
AT (1) AT345997B (en, 2012)
BE (1) BE823715A (en, 2012)
CA (1) CA1033725A (en, 2012)
CH (1) CH609345A5 (en, 2012)
DE (1) DE2459630C3 (en, 2012)
DK (1) DK138895B (en, 2012)
FR (1) FR2255072B1 (en, 2012)
GB (1) GB1436820A (en, 2012)
HU (1) HU168767B (en, 2012)
NL (1) NL7416120A (en, 2012)
SE (1) SE417966B (en, 2012)
SU (1) SU604492A3 (en, 2012)
YU (1) YU335774A (en, 2012)
ZA (1) ZA748053B (en, 2012)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
PH21123A (en) * 1983-04-28 1987-07-27 Erba Farmitalia Ergoline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5126479Y2 (en, 2012) * 1971-11-18 1976-07-05
BE792188A (fr) * 1971-12-02 1973-06-01 Farmaceutici Italia Derives de l'ergoline

Also Published As

Publication number Publication date
DE2459630C3 (de) 1981-05-07
HU168767B (en, 2012) 1976-07-28
DK138895B (da) 1978-11-13
SE417966B (sv) 1981-04-27
YU335774A (en) 1982-05-31
AT345997B (de) 1978-10-10
DK664474A (en, 2012) 1975-09-08
FR2255072B1 (en, 2012) 1978-07-28
ATA1010974A (de) 1978-02-15
NL7416120A (nl) 1975-06-24
FR2255072A1 (en, 2012) 1975-07-18
CA1033725A (en) 1978-06-27
AU7659174A (en) 1976-06-24
ZA748053B (en) 1976-01-28
CH609345A5 (en) 1979-02-28
BE823715A (fr) 1975-06-20
GB1436820A (en) 1976-05-26
JPS5095299A (en, 2012) 1975-07-29
DE2459630A1 (de) 1975-07-03
DE2459630B2 (de) 1980-07-10
SE7416084L (en, 2012) 1975-06-23
DK138895C (en, 2012) 1979-04-30
SU604492A3 (ru) 1978-04-25

Similar Documents

Publication Publication Date Title
EP0241053B1 (en) Aryl-substituted (n-piperidinyl)-methyl- and (n-piperazinyl) methylazoles having antipsychotic properties
EP0163599B1 (en) Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
US4636563A (en) Antipsychotic γ-carbolines
EP0070562B1 (en) Ergoline derivatives, processes for their preparation and pharmaceutical compositions containing them
US4690924A (en) 1,7-Naphthyridine derivatives and medicinal preparations containing same
JPS623153B2 (en, 2012)
US3853898A (en) 3-(2-substituted amino) pyridyl-phenyl ketone imines
JPS6027676B2 (ja) ピリミジノアミノメチルエルゴリン誘導体の製法
US3996228A (en) Pyrimidinoaminoethyl ergoline derivatives
JPH05504360A (ja) オキソ―テトラヒドロピリダジニル―ピラゾロ［４，３―ｂ］―１，４―ベンズオキサジン
EP0244352B1 (en) Pyrido[4,3-d]pyrimidine derivatives
IE42372B1 (en) Ergoline derivatives
JPS61254585A (ja) 三環式誘導体
JPH0344392A (ja) ４Ｈ‐インドロ〔１，２‐ｄ〕〔１，２，４〕トリアゾロ〔４，３‐ａ〕〔１，４〕ベンゾジアゼピンおよびその製造法
US4629789A (en) Alkyl substituted pyridazinones and pharmaceutical compositions
US4507308A (en) Analgesically or anti-inflammatory effective 4-quinolyl anthranilic acid derivatives
EP0124208B1 (en) Quinoline derivatives
US3957785A (en) Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
JPS61158980A (ja) ８α‐アシルアミノエルゴリン類、その製法および医薬組成物
US5414002A (en) 5- or 6-substituted β-carboline-3-carboxylic acid esters
JPS5857380A (ja) ９，１０−置換２−メシチルイミノ−３−アルキル−３，４，６，７−テトラヒドロ−２Ｈ−ピリミド（６．１−ａ）イソキノリン−４−オン
CA1140124A (en) Process for the preparation of nitrogen bridgehead condensed pyrimidine compounds, the salt, hydrates and isomers thereof, certain representatives of the compounds prepared and pharmaceutical compositions containing them
JP2875605B2 (ja) ３―エキソメチレンピロロ［２，１―ｂ］チアゾール誘導体
Monge et al. Synthesis of 6‐amino‐2‐aryl‐1, 2‐dihydro‐3H‐pyrido [2, 3‐d] pyrimidin‐4‐one derivatives
US4720496A (en) Pyridotriazoloquinazolines and triazolopyridoquinazolines useful as antiallergics