JPS60147651A - 体液中総蛋白およびアミノ酸の検出用試験紙およびその製造方法 - Google Patents
体液中総蛋白およびアミノ酸の検出用試験紙およびその製造方法Info
- Publication number
- JPS60147651A JPS60147651A JP396584A JP396584A JPS60147651A JP S60147651 A JPS60147651 A JP S60147651A JP 396584 A JP396584 A JP 396584A JP 396584 A JP396584 A JP 396584A JP S60147651 A JPS60147651 A JP S60147651A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- test paper
- soln
- tnbs
- urine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 40
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 37
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 37
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 150000001413 amino acids Chemical class 0.000 title claims abstract description 8
- 210000001124 body fluid Anatomy 0.000 title claims description 4
- 239000010839 body fluid Substances 0.000 title claims description 4
- NHJVRSWLHSJWIN-UHFFFAOYSA-N 2,4,6-trinitrobenzenesulfonic acid Chemical compound OS(=O)(=O)C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O NHJVRSWLHSJWIN-UHFFFAOYSA-N 0.000 claims abstract description 19
- 230000002745 absorbent Effects 0.000 claims description 10
- 239000002250 absorbent Substances 0.000 claims description 10
- 239000007853 buffer solution Substances 0.000 claims description 8
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Substances [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 claims 1
- -1 nitrobenzene sulfone Chemical class 0.000 claims 1
- 210000002700 urine Anatomy 0.000 abstract description 14
- 239000000872 buffer Substances 0.000 abstract description 10
- 125000003277 amino group Chemical group 0.000 abstract description 5
- 238000001514 detection method Methods 0.000 abstract description 4
- 229920000642 polymer Polymers 0.000 abstract description 4
- 238000005470 impregnation Methods 0.000 abstract description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 abstract description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 abstract description 2
- 239000004745 nonwoven fabric Substances 0.000 abstract description 2
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 abstract description 2
- 238000007689 inspection Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 11
- 102000009027 Albumins Human genes 0.000 description 6
- 108010088751 Albumins Proteins 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000012488 sample solution Substances 0.000 description 5
- 108010094139 tumor-globulin Proteins 0.000 description 5
- 238000011161 development Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000000969 carrier Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 150000002337 glycosamines Chemical class 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000012086 standard solution Substances 0.000 description 2
- 102000002572 Alpha-Globulins Human genes 0.000 description 1
- 108010068307 Alpha-Globulins Proteins 0.000 description 1
- 102000006734 Beta-Globulins Human genes 0.000 description 1
- 108010087504 Beta-Globulins Proteins 0.000 description 1
- FZQTUXCTDNATJB-UHFFFAOYSA-L C([O-])([O-])=O.[Na+].B(O)(O)O.B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+] Chemical compound C([O-])([O-])=O.[Na+].B(O)(O)O.B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+] FZQTUXCTDNATJB-UHFFFAOYSA-L 0.000 description 1
- 208000007342 Diabetic Nephropathies Diseases 0.000 description 1
- 102000008100 Human Serum Albumin Human genes 0.000 description 1
- 108091006905 Human Serum Albumin Proteins 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- KCYVWOGSBHYOSQ-UHFFFAOYSA-M [Cl-].[Na+].B([O-])(O)O.B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+].B(O)(O)O Chemical compound [Cl-].[Na+].B([O-])(O)O.B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+].B(O)(O)O KCYVWOGSBHYOSQ-UHFFFAOYSA-M 0.000 description 1
- QAFNWICQHQGPFC-UHFFFAOYSA-N [Na+].[K+].OB(O)O.OB(O)O.OB(O)O.OB([O-])[O-].OP(O)(O)=O Chemical compound [Na+].[K+].OB(O)O.OB(O)O.OB(O)O.OB([O-])[O-].OP(O)(O)=O QAFNWICQHQGPFC-UHFFFAOYSA-N 0.000 description 1
- SKFFTSBCHLPDDR-UHFFFAOYSA-L [OH-].[Na+].[Cl-].[K+].OB(O)O Chemical compound [OH-].[Na+].[Cl-].[K+].OB(O)O SKFFTSBCHLPDDR-UHFFFAOYSA-L 0.000 description 1
- GODUBWXALOQOFT-UHFFFAOYSA-M [OH-].[Na+].[Na+].OB(O)O.OB(O)O.OB(O)O.OB(O)[O-] Chemical compound [OH-].[Na+].[Na+].OB(O)O.OB(O)O.OB(O)O.OB(O)[O-] GODUBWXALOQOFT-UHFFFAOYSA-M 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000009535 clinical urine test Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 239000002274 desiccant Substances 0.000 description 1
- 208000033679 diabetic kidney disease Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- UQGFMSUEHSUPRD-UHFFFAOYSA-N disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane Chemical compound [Na+].[Na+].O1B([O-])OB2OB([O-])OB1O2 UQGFMSUEHSUPRD-UHFFFAOYSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 229910052920 inorganic sulfate Inorganic materials 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- QTEMHKDTRJWUPI-UHFFFAOYSA-M potassium sodium boric acid dihydrogen borate dihydrogen phosphate Chemical compound P(=O)(O)(O)[O-].[K+].B([O-])(O)O.B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+] QTEMHKDTRJWUPI-UHFFFAOYSA-M 0.000 description 1
- IOEGHCULCGKCNQ-UHFFFAOYSA-L potassium sodium boric acid hydrogen carbonate chloride Chemical compound [Na+].[Cl-].[K+].OB(O)O.OC([O-])=O IOEGHCULCGKCNQ-UHFFFAOYSA-L 0.000 description 1
- BUCIWTBCUUHRHZ-UHFFFAOYSA-K potassium;disodium;dihydrogen phosphate;hydrogen phosphate Chemical compound [Na+].[Na+].[K+].OP(O)([O-])=O.OP([O-])([O-])=O BUCIWTBCUUHRHZ-UHFFFAOYSA-K 0.000 description 1
- LJSOLTRJEQZSHV-UHFFFAOYSA-L potassium;sodium;hydron;hydroxide;phosphate Chemical compound [OH-].[Na+].[K+].OP(O)([O-])=O LJSOLTRJEQZSHV-UHFFFAOYSA-L 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000002331 protein detection Methods 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- WCTAGTRAWPDFQO-UHFFFAOYSA-K trisodium;hydrogen carbonate;carbonate Chemical compound [Na+].[Na+].[Na+].OC([O-])=O.[O-]C([O-])=O WCTAGTRAWPDFQO-UHFFFAOYSA-K 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP396584A JPS60147651A (ja) | 1984-01-12 | 1984-01-12 | 体液中総蛋白およびアミノ酸の検出用試験紙およびその製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP396584A JPS60147651A (ja) | 1984-01-12 | 1984-01-12 | 体液中総蛋白およびアミノ酸の検出用試験紙およびその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60147651A true JPS60147651A (ja) | 1985-08-03 |
| JPH043504B2 JPH043504B2 (enrdf_load_stackoverflow) | 1992-01-23 |
Family
ID=11571790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP396584A Granted JPS60147651A (ja) | 1984-01-12 | 1984-01-12 | 体液中総蛋白およびアミノ酸の検出用試験紙およびその製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60147651A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000077516A1 (en) * | 1999-06-11 | 2000-12-21 | Acaris Healthcare Solutions Plc | Allergen detection |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57175129A (en) * | 1981-04-19 | 1982-10-28 | Kyoto Daiichi Kagaku:Kk | Composition for testing carious activity |
| JPS57211067A (en) * | 1982-03-01 | 1982-12-24 | Terumo Corp | Test specimen for detection of ketone body |
| JPS6040953A (ja) * | 1983-08-15 | 1985-03-04 | Yasuda Saburo | 体液中物質半定量用試験紙 |
-
1984
- 1984-01-12 JP JP396584A patent/JPS60147651A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57175129A (en) * | 1981-04-19 | 1982-10-28 | Kyoto Daiichi Kagaku:Kk | Composition for testing carious activity |
| JPS57211067A (en) * | 1982-03-01 | 1982-12-24 | Terumo Corp | Test specimen for detection of ketone body |
| JPS6040953A (ja) * | 1983-08-15 | 1985-03-04 | Yasuda Saburo | 体液中物質半定量用試験紙 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000077516A1 (en) * | 1999-06-11 | 2000-12-21 | Acaris Healthcare Solutions Plc | Allergen detection |
| AU769090B2 (en) * | 1999-06-11 | 2004-01-15 | Acaris Healthcare Solutions Plc | Allergen detection |
| US7195922B1 (en) | 1999-06-11 | 2007-03-27 | City Technology Limited | Allergen detection |
| US7807103B2 (en) | 1999-06-11 | 2010-10-05 | Life Safety Distribution Ag | Allergen detection apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH043504B2 (enrdf_load_stackoverflow) | 1992-01-23 |
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