JPS6013711A - コルチコステロイドを含有する浸透局所製薬組成物 - Google Patents
コルチコステロイドを含有する浸透局所製薬組成物Info
- Publication number
- JPS6013711A JPS6013711A JP12658484A JP12658484A JPS6013711A JP S6013711 A JPS6013711 A JP S6013711A JP 12658484 A JP12658484 A JP 12658484A JP 12658484 A JP12658484 A JP 12658484A JP S6013711 A JPS6013711 A JP S6013711A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- compound
- cell envelope
- diol
- envelope disordering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 239000008194 pharmaceutical composition Substances 0.000 claims description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 6
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- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 claims description 5
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 claims description 4
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- 229960005205 prednisolone Drugs 0.000 claims description 4
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims description 4
- YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 claims description 4
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- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- 229960004555 rutoside Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 206010040400 serum sickness Diseases 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 239000003270 steroid hormone Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 229940125379 topical corticosteroid Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50627483A | 1983-06-21 | 1983-06-21 | |
| US506274 | 1983-06-24 | ||
| US576065 | 1984-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6013711A true JPS6013711A (ja) | 1985-01-24 |
| JPH0481569B2 JPH0481569B2 (enrdf_load_stackoverflow) | 1992-12-24 |
Family
ID=24013915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12658484A Granted JPS6013711A (ja) | 1983-06-21 | 1984-06-21 | コルチコステロイドを含有する浸透局所製薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6013711A (enrdf_load_stackoverflow) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63126832A (ja) * | 1986-08-27 | 1988-05-30 | ワ−ナ−−ランバ−ト・コンパニ− | 浸透増強系 |
| JPS6476894A (en) * | 1987-09-18 | 1989-03-22 | Kai Cutlery Center Co | Safety razor |
| JPS6476893A (en) * | 1987-09-18 | 1989-03-22 | Kai Cutlery Center Co | Safety razor |
| JPH01209093A (ja) * | 1988-02-18 | 1989-08-22 | Kaijirushi Hamono Kaihatsu Center:Kk | 安全かみそり |
| JPH02501739A (ja) * | 1987-05-21 | 1990-06-14 | シェリング・コーポレーション | ステロイドローション剤 |
| US7971363B2 (en) | 2005-09-09 | 2011-07-05 | Kai R&D Center Co., Ltd. | Oscillating razor |
| JP2011521999A (ja) * | 2008-06-02 | 2011-07-28 | インターベツト・インターナシヨナル・ベー・ベー | 抗生物質およびコルチコステロイドを含む組成物 |
| JP2014516962A (ja) * | 2011-05-16 | 2014-07-17 | パールマン，デール，エル． | 皮膚疾患の処置のための組成物及び方法 |
| JP2015506972A (ja) * | 2012-02-13 | 2015-03-05 | ダイアーナル リミテッドＤｉｕｒｎａｌ Ｌｉｍｉｔｅｄ | ハイドロコーチゾンの制御放出製剤 |
-
1984
- 1984-06-21 JP JP12658484A patent/JPS6013711A/ja active Granted
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63126832A (ja) * | 1986-08-27 | 1988-05-30 | ワ−ナ−−ランバ−ト・コンパニ− | 浸透増強系 |
| JPH02501739A (ja) * | 1987-05-21 | 1990-06-14 | シェリング・コーポレーション | ステロイドローション剤 |
| JPS6476894A (en) * | 1987-09-18 | 1989-03-22 | Kai Cutlery Center Co | Safety razor |
| JPS6476893A (en) * | 1987-09-18 | 1989-03-22 | Kai Cutlery Center Co | Safety razor |
| JPH01209093A (ja) * | 1988-02-18 | 1989-08-22 | Kaijirushi Hamono Kaihatsu Center:Kk | 安全かみそり |
| US7971363B2 (en) | 2005-09-09 | 2011-07-05 | Kai R&D Center Co., Ltd. | Oscillating razor |
| JP2011521999A (ja) * | 2008-06-02 | 2011-07-28 | インターベツト・インターナシヨナル・ベー・ベー | 抗生物質およびコルチコステロイドを含む組成物 |
| JP2014516962A (ja) * | 2011-05-16 | 2014-07-17 | パールマン，デール，エル． | 皮膚疾患の処置のための組成物及び方法 |
| JP2015506972A (ja) * | 2012-02-13 | 2015-03-05 | ダイアーナル リミテッドＤｉｕｒｎａｌ Ｌｉｍｉｔｅｄ | ハイドロコーチゾンの制御放出製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0481569B2 (enrdf_load_stackoverflow) | 1992-12-24 |
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