JPS60120890A - 新規ホスホリル化剤 - Google Patents

新規ホスホリル化剤

Info

Publication number
JPS60120890A
JPS60120890A JP22839583A JP22839583A JPS60120890A JP S60120890 A JPS60120890 A JP S60120890A JP 22839583 A JP22839583 A JP 22839583A JP 22839583 A JP22839583 A JP 22839583A JP S60120890 A JPS60120890 A JP S60120890A
Authority
JP
Japan
Prior art keywords
nucleoside
formula
compound
reacting
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP22839583A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0372235B2 (fr
Inventor
Hiroshi Takaku
洋 高久
Takeshi Noda
剛 野田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANKYO KAGAKU KK
Original Assignee
SANKYO KAGAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SANKYO KAGAKU KK filed Critical SANKYO KAGAKU KK
Priority to JP22839583A priority Critical patent/JPS60120890A/ja
Publication of JPS60120890A publication Critical patent/JPS60120890A/ja
Publication of JPH0372235B2 publication Critical patent/JPH0372235B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)
JP22839583A 1983-12-05 1983-12-05 新規ホスホリル化剤 Granted JPS60120890A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP22839583A JPS60120890A (ja) 1983-12-05 1983-12-05 新規ホスホリル化剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22839583A JPS60120890A (ja) 1983-12-05 1983-12-05 新規ホスホリル化剤

Publications (2)

Publication Number Publication Date
JPS60120890A true JPS60120890A (ja) 1985-06-28
JPH0372235B2 JPH0372235B2 (fr) 1991-11-18

Family

ID=16875793

Family Applications (1)

Application Number Title Priority Date Filing Date
JP22839583A Granted JPS60120890A (ja) 1983-12-05 1983-12-05 新規ホスホリル化剤

Country Status (1)

Country Link
JP (1) JPS60120890A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0291088A (ja) * 1988-09-29 1990-03-30 Central Glass Co Ltd ホスファイトおよびヌクレオシド‐３’‐ホスファイト誘導体およびこれを用いるオリゴヌクレオチドの合成法
JPH0594874U (ja) * 1992-05-15 1993-12-24 桜井株式会社 控え付きラベル

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0291088A (ja) * 1988-09-29 1990-03-30 Central Glass Co Ltd ホスファイトおよびヌクレオシド‐３’‐ホスファイト誘導体およびこれを用いるオリゴヌクレオチドの合成法
JPH0594874U (ja) * 1992-05-15 1993-12-24 桜井株式会社 控え付きラベル

Also Published As

Publication number Publication date
JPH0372235B2 (fr) 1991-11-18

Similar Documents

Publication Publication Date Title
EP2753607B1 (fr) REACTIFS BICYCLO[6.1.0]NON-4-YNE DESTINES A DES & xA; MODIFICATIONS CHIMIQUES D'OLIGONUCLÉOTIDES
CA1155442A (fr) Agent de combinaison nucleosidique et methodes
JPS63179889A (ja) オリゴヌクレオチドの製造法
JPH0812698A (ja) インビトロにおけるオリゴヌクレオチド合成法
WO2006022323A1 (fr) Compose de phosphoramidite et procede de fabrication d’oligo-arn
IKEHARA et al. Studies of nucleosides and nucleotides. LXXXII. Cyclonucleosides.(39). Synthesis and Properties of 2'-halogeno-2'-deoxyadenosines
JPH0631305B2 (ja) ヌクレオシド誘導体
CA2192950A1 (fr) Nouveau procede de production de nucleosides connus et nouveaux, modifies en position 2' par deplacement nucleophile intramoleculaire
JPH03501128A (ja) ヌクレオシドおよびポリヌクレオチドチオホスホラミダイトおよびホスホロジチオエイト化合物並びに方法
Daskalov et al. Synthesis and properties of O6-substituted guanosine derivatives.
WO1988003149A1 (fr) Procede de synthese d'oligonucleotides et composes servant a former des groupes protecteurs a poids moleculaire eleve
WO2020235658A1 (fr) Blocmère multifluoré utilisé dans la synthèse d'oligonucléotides et procédé de synthèse d'oligonucléotides l'utilisant
US4419509A (en) Process for de-cyanoethylating blocked nucleotides
JPS60120890A (ja) 新規ホスホリル化剤
Hancox et al. Some reactions of 4′-thionucleosides and their sulfones
JPH0291088A (ja) ホスファイトおよびヌクレオシド‐３’‐ホスファイト誘導体およびこれを用いるオリゴヌクレオチドの合成法
JPS5841896A (ja) 保護されたヌクレオチドを脱シアノエチル化する方法
Welch et al. Synthesis of an mRNA fragment of alanyl-tRNA synthetase gene in Escherichia coli using the 6-methyl-3-pyridyl group for protection of the imide functions of uridine and guanosine
JPS6251695A (ja) ホスホロアミダイト類の合成法
JPS60120897A (ja) 新規なヌクレオシド３′−ホスフエ−トの製造方法
Sekine et al. Synthesis of oligoribonucleotides by use of 4, 4', 4"-tris (acyloxy) trityl groups for protection of the 6-amino group of adenosine.
Dabkowski et al. Synthesis of phosphorofluoridates and phosphorofluoridothioates via the phosphoramidite approach
JPH06135988A (ja) ヌクレオシド誘導体
JPS6284097A (ja) 保護されたオリゴヌクレオチドの製造法
EP4186914A1 (fr) Procédé de production de polynucleotides

Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees