JPS5946237B2 - セフアロスポリン誘導体およびその製造法 - Google Patents
セフアロスポリン誘導体およびその製造法Info
- Publication number
- JPS5946237B2 JPS5946237B2 JP51037374A JP3737476A JPS5946237B2 JP S5946237 B2 JPS5946237 B2 JP S5946237B2 JP 51037374 A JP51037374 A JP 51037374A JP 3737476 A JP3737476 A JP 3737476A JP S5946237 B2 JPS5946237 B2 JP S5946237B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- cephem
- solution
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51037374A JPS5946237B2 (ja) | 1976-04-02 | 1976-04-02 | セフアロスポリン誘導体およびその製造法 |
| MX775580U MX4409E (es) | 1976-04-02 | 1977-03-25 | Procedimiento para preparar derivados de cefalosporina |
| GR53093A GR66409B (US20110158925A1-20110630-C00042.png) | 1976-04-02 | 1977-03-26 | |
| NO771111A NO153259C (no) | 1976-04-02 | 1977-03-29 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme cefalosporinderivater |
| AU23723/77A AU510278B2 (en) | 1976-04-02 | 1977-03-29 | Cephalosporin derivatives |
| NL7703474A NL7703474A (nl) | 1976-04-02 | 1977-03-30 | Cefalosporine-derivaat, werkwijze voor het berei- den ervan, werkwijze voor het bereiden van een farmaceutisch preparaat met toepassing ervan als- mede zo verkregen gevormd preparaat. |
| SE7703689A SE433354B (sv) | 1976-04-02 | 1977-03-30 | Forfarande for framstellning av cefalosporinderivat |
| CH397277A CH631717A5 (de) | 1976-04-02 | 1977-03-30 | Verfahren zur herstellung von cephalosporinderivaten. |
| DE2714419A DE2714419C2 (de) | 1976-04-02 | 1977-03-31 | Cephalosporinderivate, Verfahren zu deren Herstellung und Arzneimittel |
| GB13688/77A GB1525687A (en) | 1976-04-02 | 1977-03-31 | Cephalosporin derivatives |
| US05/783,230 US4172891A (en) | 1976-04-02 | 1977-03-31 | Cephalosporins |
| FR7709744A FR2361403A1 (fr) | 1976-04-02 | 1977-03-31 | 7-12-(2-imino-3-hydroxy-4-thiazolin-4-ml)-acetamido) antibiotiques |
| BE1008055A BE853073A (fr) | 1976-04-02 | 1977-03-31 | Cephalosporines |
| ZA00771993A ZA771993B (en) | 1976-04-02 | 1977-04-01 | Cephalosporins |
| CA275,315A CA1127149A (en) | 1976-04-02 | 1977-04-01 | Cephalosporins |
| PH19619A PH13024A (en) | 1976-04-02 | 1977-04-01 | Cephalosporins |
| DK144577A DK144577A (da) | 1976-04-02 | 1977-04-01 | Cephalosporinderivater og fremgangsmade til fremstilling deraf |
| ES457473A ES457473A1 (es) | 1976-04-02 | 1977-04-01 | Un procedimiento para preparar derivados de cefalosporina. |
| HU77TA1433A HU179596B (en) | 1976-04-02 | 1977-04-01 | Process for preparing 7-acetamido-3-methyl-cef-3-eme-4-carboxylic acid derivatives |
| FI771023A FI66006C (fi) | 1976-04-02 | 1977-04-01 | Foerfarande foer framstaellning av 7-(2-(2-imino-3-hydroxi-4-tiazolin-4-yl)-acetamido)cefalosporiner anvaendbara saosom anibiotika |
| PT66392A PT66392B (en) | 1976-04-02 | 1977-04-02 | Cephalosporin |
| AT234677A AT351677B (de) | 1976-04-02 | 1977-04-04 | Verfahren zur herstellung von neuen cephalos- porinderivaten |
| FR7800580A FR2369282A1 (fr) | 1976-04-02 | 1978-01-10 | Derives halogenes de 3-carbamoyloxycephalosporines |
| US06/044,215 US4239758A (en) | 1976-04-02 | 1979-05-31 | Cephalosporins |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51037374A JPS5946237B2 (ja) | 1976-04-02 | 1976-04-02 | セフアロスポリン誘導体およびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS52122389A JPS52122389A (en) | 1977-10-14 |
| JPS5946237B2 true JPS5946237B2 (ja) | 1984-11-10 |
Family
ID=12495730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51037374A Expired JPS5946237B2 (ja) | 1976-04-02 | 1976-04-02 | セフアロスポリン誘導体およびその製造法 |
Country Status (22)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5946237B2 (ja) * | 1976-04-02 | 1984-11-10 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
| IL61458A0 (en) * | 1979-12-07 | 1980-12-31 | Erba Farmitalia | N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them |
| IT1148888B (it) * | 1980-07-15 | 1986-12-03 | Schiena Ricerche Di | Composti antibiotici |
| NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2518130A (en) * | 1945-04-26 | 1950-08-08 | Evans | N-oxides of tertiary amines and process of preparing same |
| US2500131A (en) * | 1945-06-27 | 1950-03-07 | Ralph L Evans | Di-nu-oxides of amino-substituted acridines and quinolines |
| NZ176206A (en) * | 1973-12-25 | 1978-03-06 | Takeda Chemical Industries Ltd | Cephalosporins |
| JPS5119765A (en) * | 1974-08-09 | 1976-02-17 | Takeda Chemical Industries Ltd | Aminochiazoorujudotaino seizoho |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| JPS5946237B2 (ja) * | 1976-04-02 | 1984-11-10 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
-
1976
- 1976-04-02 JP JP51037374A patent/JPS5946237B2/ja not_active Expired
-
1977
- 1977-03-25 MX MX775580U patent/MX4409E/es unknown
- 1977-03-26 GR GR53093A patent/GR66409B/el unknown
- 1977-03-29 AU AU23723/77A patent/AU510278B2/en not_active Expired
- 1977-03-29 NO NO771111A patent/NO153259C/no unknown
- 1977-03-30 SE SE7703689A patent/SE433354B/xx not_active IP Right Cessation
- 1977-03-30 NL NL7703474A patent/NL7703474A/xx not_active Application Discontinuation
- 1977-03-30 CH CH397277A patent/CH631717A5/de not_active IP Right Cessation
- 1977-03-31 BE BE1008055A patent/BE853073A/xx not_active IP Right Cessation
- 1977-03-31 GB GB13688/77A patent/GB1525687A/en not_active Expired
- 1977-03-31 FR FR7709744A patent/FR2361403A1/fr active Granted
- 1977-03-31 DE DE2714419A patent/DE2714419C2/de not_active Expired
- 1977-03-31 US US05/783,230 patent/US4172891A/en not_active Expired - Lifetime
- 1977-04-01 DK DK144577A patent/DK144577A/da not_active Application Discontinuation
- 1977-04-01 PH PH19619A patent/PH13024A/en unknown
- 1977-04-01 ES ES457473A patent/ES457473A1/es not_active Expired
- 1977-04-01 HU HU77TA1433A patent/HU179596B/hu not_active IP Right Cessation
- 1977-04-01 ZA ZA00771993A patent/ZA771993B/xx unknown
- 1977-04-01 CA CA275,315A patent/CA1127149A/en not_active Expired
- 1977-04-01 FI FI771023A patent/FI66006C/fi not_active IP Right Cessation
- 1977-04-02 PT PT66392A patent/PT66392B/pt unknown
- 1977-04-04 AT AT234677A patent/AT351677B/de active
-
1978
- 1978-01-10 FR FR7800580A patent/FR2369282A1/fr active Granted
-
1979
- 1979-05-31 US US06/044,215 patent/US4239758A/en not_active Expired - Lifetime
Also Published As
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| US4264595A (en) | 7-[2-(2-Imino-4-thiazolin-4-yl)-2-(syn)-hydroxy-iminoacetamido]-cephalosporins | |
| US4080498A (en) | 7-Alpha-(2-aminothiazole)-acetamido-cephalosporins | |
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| US4245088A (en) | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | |
| GB2051810A (en) | Cephalosporin compounds processes for their preparation and antibacterial drugs containing them | |
| US4758557A (en) | Cephalosporin derivatives and bactericides containing the same | |
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