JPS5937077B2 - ６−デオキシネオマイシン、その製造法及びそれを有効成分とする抗菌剤 - Google Patents

６−デオキシネオマイシン、その製造法及びそれを有効成分とする抗菌剤

Info

Publication number
JPS5937077B2
JPS5937077B2 JP52027528A JP2752877A JPS5937077B2 JP S5937077 B2 JPS5937077 B2 JP S5937077B2 JP 52027528 A JP52027528 A JP 52027528A JP 2752877 A JP2752877 A JP 2752877A JP S5937077 B2 JPS5937077 B2 JP S5937077B2
Authority
JP
Japan
Prior art keywords
deoxyneomycin
formula
acid addition
tables
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52027528A
Other languages
English (en)
Japanese (ja)
Other versions
JPS52142044A (en
Inventor
ステフアン・ジエロ−
ダニエル・メルシエ
アレ−ン・オレスケ
アンドレ・シ−ル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of JPS52142044A publication Critical patent/JPS52142044A/ja
Publication of JPS5937077B2 publication Critical patent/JPS5937077B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/232—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP52027528A 1976-03-11 1977-03-11 ６−デオキシネオマイシン、その製造法及びそれを有効成分とする抗菌剤 Expired JPS5937077B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9859/76A GB1549320A (en) 1976-03-11 1976-03-11 Aminoglycoside antibiotic compounds and process for preparing the same
GB000009859/76 1976-03-11

Publications (2)

Publication Number Publication Date
JPS52142044A JPS52142044A (en) 1977-11-26
JPS5937077B2 true JPS5937077B2 (ja) 1984-09-07

Family

ID=9880112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52027528A Expired JPS5937077B2 (ja) 1976-03-11 1977-03-11 ６−デオキシネオマイシン、その製造法及びそれを有効成分とする抗菌剤

Country Status (16)

Country Link
JP (1) JPS5937077B2 (de)
BE (1) BE852142A (de)
CA (1) CA1068226A (de)
CH (1) CH620944A5 (de)
DD (1) DD130047A5 (de)
DE (1) DE2710694C2 (de)
ES (1) ES456743A1 (de)
FR (1) FR2343751A1 (de)
GB (1) GB1549320A (de)
HU (1) HU178039B (de)
IT (1) IT1114756B (de)
NL (1) NL7702341A (de)
NO (1) NO148558C (de)
PL (1) PL104557B1 (de)
SE (1) SE433091B (de)
SU (1) SU952109A3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109111376B (zh) * 2018-09-18 2021-09-14 四川医立特生物医药有限公司 一种2,5-双脱氧链霉胺衍生物及其应用

Also Published As

Publication number Publication date
HU178039B (en) 1982-02-28
SE433091B (sv) 1984-05-07
CA1068226A (en) 1979-12-18
CH620944A5 (en) 1980-12-31
NO148558B (no) 1983-07-25
DD130047A5 (de) 1978-03-01
NL7702341A (nl) 1977-09-13
DE2710694A1 (de) 1977-09-15
DE2710694C2 (de) 1985-08-01
GB1549320A (en) 1979-08-01
FR2343751A1 (fr) 1977-10-07
JPS52142044A (en) 1977-11-26
SE7702721L (sv) 1977-09-12
ES456743A1 (es) 1978-06-01
PL196605A1 (pl) 1978-02-13
PL104557B1 (pl) 1979-08-31
SU952109A3 (ru) 1982-08-15
NO148558C (no) 1983-11-02
NO770852L (no) 1977-09-13
BE852142A (fr) 1977-09-07
FR2343751B1 (de) 1981-10-16
IT1114756B (it) 1986-01-27

Similar Documents

Publication Publication Date Title
Rinehart Jr Mutasynthesis of new antibiotics
L Jr et al. Biosynthesis of aminocyclitol antibiotics
Testa et al. Biotransformation, a new approach to aminoglycoside biosynthesis. I. Sisomicin
US3784541A (en) Polyamine compounds and methods for their production
US3669838A (en) Method of making antibiotics containing the aminocyclitol subunit
US4425430A (en) Process for production of antibiotics and novel antibiotics produced thereby
US3981861A (en) Antibiotic aminoglycosides, processes of preparation and pharmaceutical compositions
US4170643A (en) Aminoglycoside-aminocyclitol derivatives and method of use
US3541078A (en) Amine compounds and methods for their production
US4216308A (en) Fortimicin factors D and KE compounds
JPS5937077B2 (ja) ６−デオキシネオマイシン、その製造法及びそれを有効成分とする抗菌剤
US4146617A (en) Desoxystreptamine derivatives, salts, pharmaceutical compositions and method of use
GB2059956A (en) Fortimicin derivatives
US3987029A (en) Antibacterial antibiotics AM31α, AM31β and AM31γ
US4209511A (en) Aminoglycoside antibiotics and process for production thereof
US4048015A (en) Fortimicin C and process for production thereof
Perlman et al. MICROBIAL PRODUCTION OF VITAMIN B12 ANTIMETABOLITES. IN 5-HYDROXY-L-ARGININE FROM BACILLUS CEREUS 439
NARA Aminoglycoside antibiotics
Takeda et al. BIOSYNTHESIS OF BUTIROSINS. I BIOSYNTHETIC PATHWAYS OF BUTIROSINS AND RELATED ANTIBIOTICS
US4241182A (en) Fortimicin factors KG1, KG2 and KG3 and processes for production thereof
US4310661A (en) Antibiotics XK-62-3 and XK-62-4 and process for production thereof
US4217446A (en) ωAmino-2-hydroxyalkyl derivatives of aminoglycoside antibiotics
US3743634A (en) 2-deoxystreptamine derivative and acid-addition salts
USRE29903E (en) Antibacterial antibiotics AM31α, AM31β and AM31γ
US4209612A (en) Fortimicin factors KF and KG and process for production thereof