CA1068226A - Aminoglycoside-aminocyclitol derivatives and process for preparing the same - Google Patents

Aminoglycoside-aminocyclitol derivatives and process for preparing the same

Info

Publication number
CA1068226A
CA1068226A CA273,830A CA273830A CA1068226A CA 1068226 A CA1068226 A CA 1068226A CA 273830 A CA273830 A CA 273830A CA 1068226 A CA1068226 A CA 1068226A
Authority
CA
Canada
Prior art keywords
process according
mixture
deoxyneomycin
free base
streptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA273,830A
Other languages
English (en)
French (fr)
Inventor
Daniel Mercier
Alain Olesker
Stephan Gero
Andre Cier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Application granted granted Critical
Publication of CA1068226A publication Critical patent/CA1068226A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/232—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA273,830A 1976-03-11 1977-03-10 Aminoglycoside-aminocyclitol derivatives and process for preparing the same Expired CA1068226A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9859/76A GB1549320A (en) 1976-03-11 1976-03-11 Aminoglycoside antibiotic compounds and process for preparing the same

Publications (1)

Publication Number Publication Date
CA1068226A true CA1068226A (en) 1979-12-18

Family

ID=9880112

Family Applications (1)

Application Number Title Priority Date Filing Date
CA273,830A Expired CA1068226A (en) 1976-03-11 1977-03-10 Aminoglycoside-aminocyclitol derivatives and process for preparing the same

Country Status (16)

Country Link
JP (1) JPS5937077B2 (de)
BE (1) BE852142A (de)
CA (1) CA1068226A (de)
CH (1) CH620944A5 (de)
DD (1) DD130047A5 (de)
DE (1) DE2710694C2 (de)
ES (1) ES456743A1 (de)
FR (1) FR2343751A1 (de)
GB (1) GB1549320A (de)
HU (1) HU178039B (de)
IT (1) IT1114756B (de)
NL (1) NL7702341A (de)
NO (1) NO148558C (de)
PL (1) PL104557B1 (de)
SE (1) SE433091B (de)
SU (1) SU952109A3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109111376B (zh) * 2018-09-18 2021-09-14 四川医立特生物医药有限公司 一种2,5-双脱氧链霉胺衍生物及其应用

Also Published As

Publication number Publication date
DD130047A5 (de) 1978-03-01
NO148558C (no) 1983-11-02
HU178039B (en) 1982-02-28
NL7702341A (nl) 1977-09-13
DE2710694C2 (de) 1985-08-01
DE2710694A1 (de) 1977-09-15
GB1549320A (en) 1979-08-01
SU952109A3 (ru) 1982-08-15
JPS5937077B2 (ja) 1984-09-07
JPS52142044A (en) 1977-11-26
IT1114756B (it) 1986-01-27
FR2343751B1 (de) 1981-10-16
PL196605A1 (pl) 1978-02-13
ES456743A1 (es) 1978-06-01
FR2343751A1 (fr) 1977-10-07
SE7702721L (sv) 1977-09-12
NO770852L (no) 1977-09-13
SE433091B (sv) 1984-05-07
BE852142A (fr) 1977-09-07
CH620944A5 (en) 1980-12-31
PL104557B1 (pl) 1979-08-31
NO148558B (no) 1983-07-25

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