JPS59184101A - 臓器の保存解凍用装置 - Google Patents
臓器の保存解凍用装置Info
- Publication number
- JPS59184101A JPS59184101A JP5659383A JP5659383A JPS59184101A JP S59184101 A JPS59184101 A JP S59184101A JP 5659383 A JP5659383 A JP 5659383A JP 5659383 A JP5659383 A JP 5659383A JP S59184101 A JPS59184101 A JP S59184101A
- Authority
- JP
- Japan
- Prior art keywords
- organ
- temperature
- refrigerant
- container
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000056 organ Anatomy 0.000 title claims abstract description 61
- 238000010257 thawing Methods 0.000 title claims description 19
- 239000007788 liquid Substances 0.000 claims abstract description 28
- 238000007710 freezing Methods 0.000 claims abstract description 26
- 230000008014 freezing Effects 0.000 claims abstract description 23
- 239000003507 refrigerant Substances 0.000 claims abstract description 22
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims abstract description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 10
- 230000010412 perfusion Effects 0.000 claims description 35
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 238000001816 cooling Methods 0.000 claims description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 210000003240 portal vein Anatomy 0.000 claims description 6
- 210000003462 vein Anatomy 0.000 claims description 6
- 210000001367 artery Anatomy 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 239000002577 cryoprotective agent Substances 0.000 claims description 3
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 abstract description 13
- 238000000034 method Methods 0.000 abstract description 13
- 239000008280 blood Substances 0.000 abstract description 12
- 210000004369 blood Anatomy 0.000 abstract description 12
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 9
- 239000007798 antifreeze agent Substances 0.000 abstract description 6
- 229910052757 nitrogen Inorganic materials 0.000 abstract description 4
- 239000003978 infusion fluid Substances 0.000 abstract 5
- 239000000243 solution Substances 0.000 abstract 3
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 238000005273 aeration Methods 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 description 11
- 238000002054 transplantation Methods 0.000 description 5
- 230000006378 damage Effects 0.000 description 4
- 238000004321 preservation Methods 0.000 description 4
- 230000008081 blood perfusion Effects 0.000 description 3
- 230000002528 anti-freeze Effects 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- -1 Freon Chemical compound 0.000 description 1
- 238000009412 basement excavation Methods 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000002595 cold damage Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5659383A JPS59184101A (ja) | 1983-03-31 | 1983-03-31 | 臓器の保存解凍用装置 |
| CA000429420A CA1200507A (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| EP83303133A EP0096997B1 (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| DE8383303133T DE3366419D1 (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| US06/615,212 US4494385A (en) | 1982-06-04 | 1984-05-20 | Method of preserving organ and apparatus for preserving the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5659383A JPS59184101A (ja) | 1983-03-31 | 1983-03-31 | 臓器の保存解凍用装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59184101A true JPS59184101A (ja) | 1984-10-19 |
| JPS6155882B2 JPS6155882B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-11-29 |
Family
ID=13031491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5659383A Granted JPS59184101A (ja) | 1982-06-04 | 1983-03-31 | 臓器の保存解凍用装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59184101A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5107371A (en) * | 1989-06-01 | 1992-04-21 | Canon Kabushiki Kaisha | Cemented lens and process for producing the same |
-
1983
- 1983-03-31 JP JP5659383A patent/JPS59184101A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5107371A (en) * | 1989-06-01 | 1992-04-21 | Canon Kabushiki Kaisha | Cemented lens and process for producing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6155882B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-11-29 |
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