JPS5827796B2 - テオフイリニルメチルジオキソラン誘導体およびその製法 - Google Patents

テオフイリニルメチルジオキソラン誘導体およびその製法

Info

Publication number
JPS5827796B2
JPS5827796B2 JP56056896A JP5689681A JPS5827796B2 JP S5827796 B2 JPS5827796 B2 JP S5827796B2 JP 56056896 A JP56056896 A JP 56056896A JP 5689681 A JP5689681 A JP 5689681A JP S5827796 B2 JPS5827796 B2 JP S5827796B2
Authority
JP
Japan
Prior art keywords
dioxolane
derivative
compound
group
theophyrinylmethyldioxolane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56056896A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56164191A (en
Inventor
ウゴ・キオドニ
シルバーノ・スピネリ
ヨーゼ・セバスチヤン・フランツオーネ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unibios SpA
Original Assignee
Unibios SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unibios SpA filed Critical Unibios SpA
Publication of JPS56164191A publication Critical patent/JPS56164191A/ja
Publication of JPS5827796B2 publication Critical patent/JPS5827796B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56056896A 1980-04-15 1981-04-14 テオフイリニルメチルジオキソラン誘導体およびその製法 Expired JPS5827796B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21370/80A IT1195267B (it) 1980-04-15 1980-04-15 Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
JPS56164191A JPS56164191A (en) 1981-12-17
JPS5827796B2 true JPS5827796B2 (ja) 1983-06-11

Family

ID=11180793

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56056896A Expired JPS5827796B2 (ja) 1980-04-15 1981-04-14 テオフイリニルメチルジオキソラン誘導体およびその製法

Country Status (7)

Country Link
US (1) US4378359A (OSRAM)
JP (1) JPS5827796B2 (OSRAM)
BE (1) BE888417A (OSRAM)
DE (1) DE3114130A1 (OSRAM)
FR (1) FR2480286A1 (OSRAM)
GB (1) GB2078717B (OSRAM)
IT (1) IT1195267B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138397A1 (de) * 1981-09-26 1983-04-07 Hoechst Ag, 6230 Frankfurt "arzneimittel, darin enthaltene vicinale dihydroxyalkylxanthine und herstellungsverfahren fuer diese xanthinverbindungen"
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
EP0171005B1 (en) * 1984-07-27 1989-11-23 BOEHRINGER BIOCHEMIA ROBIN S.p.A. Xanthinylmethylthiazolidines, process for their preparation and pharmaceutical compositions containing them
IT1197516B (it) * 1986-12-24 1988-11-30 Abc Ist Biolog Chem Spa Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
JP2500277B2 (ja) * 1990-11-27 1996-05-29 三井東圧化学株式会社 フェノ―ル系樹脂パイプの押出成型方法および装置
US5786360A (en) 1996-11-19 1998-07-28 Link Technology Incorporated A1 adenosine receptor antagonists
WO2004074247A2 (en) 2003-02-19 2004-09-02 Endacea, Inc. A1 adenosine receptor antagonists
EP1636229A4 (en) * 2003-06-06 2008-07-30 Endacea Inc ADENOSINE A1 RECEPTOR ANTAGONISTS
EP1636230A4 (en) * 2003-06-09 2010-06-16 Endacea Inc ADENOSINE A1 RECEPTOR ANTAGONISTS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2761861A (en) * 1953-09-11 1956-09-04 Hoffmann La Roche Process for the manufacture of novel xanthine bases and salts thereof
US2840559A (en) * 1954-06-22 1958-06-24 Krantz Jr Nuclearly substituted 8-theophyllines and method of making the same
FR1523273A (fr) * 1967-03-13 1968-05-03 Soc Ind Fab Antibiotiques Sifa Nouveaux dérivés de théophylline et procédé de préparation
GB1289287A (OSRAM) * 1969-03-28 1972-09-13
IT1113122B (it) * 1978-04-06 1986-01-20 Abc Ist Biolog Chem Spa Composizione farmaceutica ad attivita' antibrocospastica e antitosse

Also Published As

Publication number Publication date
GB2078717A (en) 1982-01-13
IT8021370A0 (it) 1980-04-15
BE888417A (fr) 1981-07-31
FR2480286B1 (OSRAM) 1984-03-30
GB2078717B (en) 1984-02-15
JPS56164191A (en) 1981-12-17
DE3114130A1 (de) 1982-01-28
IT1195267B (it) 1988-10-12
US4378359A (en) 1983-03-29
FR2480286A1 (fr) 1981-10-16

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