JPS58192870A - 2−アルキルアミノ−および2−アミノ−5−アルキルピリジンの製造方法 - Google Patents
2−アルキルアミノ−および2−アミノ−5−アルキルピリジンの製造方法Info
- Publication number
- JPS58192870A JPS58192870A JP58062055A JP6205583A JPS58192870A JP S58192870 A JPS58192870 A JP S58192870A JP 58062055 A JP58062055 A JP 58062055A JP 6205583 A JP6205583 A JP 6205583A JP S58192870 A JPS58192870 A JP S58192870A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- isomer
- alkylpyridine
- sodium
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/366,599 US4405790A (en) | 1982-04-08 | 1982-04-08 | Process for preparing 2-alkylamino- and 2-amino-5-alkylpyridines |
US366599 | 1982-04-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS58192870A true JPS58192870A (ja) | 1983-11-10 |
JPH0480904B2 JPH0480904B2 (enrdf_load_stackoverflow) | 1992-12-21 |
Family
ID=23443682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP58062055A Granted JPS58192870A (ja) | 1982-04-08 | 1983-04-08 | 2−アルキルアミノ−および2−アミノ−5−アルキルピリジンの製造方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US4405790A (enrdf_load_stackoverflow) |
EP (1) | EP0091790B1 (enrdf_load_stackoverflow) |
JP (1) | JPS58192870A (enrdf_load_stackoverflow) |
CA (1) | CA1219589A (enrdf_load_stackoverflow) |
DE (1) | DE3380846D1 (enrdf_load_stackoverflow) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3374313D1 (de) * | 1982-12-23 | 1987-12-10 | Smith Kline French Lab | Aminopyrimidinone derivatives as histamine h1-antagonists |
DE4232175A1 (de) * | 1992-04-15 | 1993-10-21 | Bayer Ag | Verfahren zur Herstellung von 2-Amino-5-methyl-pyridin |
IL114314A (en) * | 1994-06-24 | 2000-12-06 | Reilly Ind Inc | Amination of pyridine bases |
RU2165414C2 (ru) * | 1994-06-24 | 2001-04-20 | Рейлли Индастриз, Инк. | Усовершенствованный способ аминирования пиридиновых оснований по чичибабину |
US5808081A (en) * | 1995-06-26 | 1998-09-15 | Reilly Industries, Inc. | Chichibabin aminations of pyridine bases |
EP1254138B1 (en) * | 2000-02-09 | 2005-05-11 | Novartis AG | Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase |
CN106496105B (zh) * | 2016-08-31 | 2019-01-11 | 南京红太阳生物化学有限责任公司 | 一种3-甲基吡啶氨化制备2-氨基-5-甲基吡啶的方法 |
CN111778720A (zh) * | 2020-07-10 | 2020-10-16 | 温州厚德服饰有限公司 | 一种防潮皮衣及其加工工艺 |
-
1982
- 1982-04-08 US US06/366,599 patent/US4405790A/en not_active Expired - Lifetime
-
1983
- 1983-04-07 EP EP83301959A patent/EP0091790B1/en not_active Expired
- 1983-04-07 DE DE8383301959T patent/DE3380846D1/de not_active Expired
- 1983-04-07 CA CA000425411A patent/CA1219589A/en not_active Expired
- 1983-04-08 JP JP58062055A patent/JPS58192870A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
CA1219589A (en) | 1987-03-24 |
DE3380846D1 (en) | 1989-12-21 |
EP0091790A3 (en) | 1984-11-14 |
EP0091790A2 (en) | 1983-10-19 |
US4405790A (en) | 1983-09-20 |
JPH0480904B2 (enrdf_load_stackoverflow) | 1992-12-21 |
EP0091790B1 (en) | 1989-11-15 |
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