JPS58148888A - 麦角アルカロイド類 - Google Patents

麦角アルカロイド類

Info

Publication number
JPS58148888A
JPS58148888A JP58021396A JP2139683A JPS58148888A JP S58148888 A JPS58148888 A JP S58148888A JP 58021396 A JP58021396 A JP 58021396A JP 2139683 A JP2139683 A JP 2139683A JP S58148888 A JPS58148888 A JP S58148888A
Authority
JP
Japan
Prior art keywords
compound
acid addition
addition salt
pharmacologically acceptable
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58021396A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0352473B2 (hu
Inventor
ルドルフ・カ−・ア−・ギガ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS58148888A publication Critical patent/JPS58148888A/ja
Publication of JPH0352473B2 publication Critical patent/JPH0352473B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP58021396A 1982-02-12 1983-02-10 麦角アルカロイド類 Granted JPS58148888A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH89382 1982-02-12
CH893/82 1982-02-12
CH6924/82 1982-11-29

Publications (2)

Publication Number Publication Date
JPS58148888A true JPS58148888A (ja) 1983-09-05
JPH0352473B2 JPH0352473B2 (hu) 1991-08-12

Family

ID=4197630

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58021396A Granted JPS58148888A (ja) 1982-02-12 1983-02-10 麦角アルカロイド類

Country Status (6)

Country Link
JP (1) JPS58148888A (hu)
BE (1) BE895842A (hu)
FR (1) FR2528850B1 (hu)
HU (1) HU187003B (hu)
SU (1) SU1189351A3 (hu)
ZA (1) ZA83955B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999053324A1 (en) * 1998-04-16 1999-10-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Salivary prolactin test for serotonergic activity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5040595A (hu) * 1973-06-28 1975-04-14
JPS5168599A (hu) * 1974-09-27 1976-06-14 Sandoz Ag

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505102A (de) * 1967-11-01 1971-03-31 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5040595A (hu) * 1973-06-28 1975-04-14
JPS5168599A (hu) * 1974-09-27 1976-06-14 Sandoz Ag

Also Published As

Publication number Publication date
FR2528850A1 (fr) 1983-12-23
JPH0352473B2 (hu) 1991-08-12
BE895842A (fr) 1983-08-08
HU187003B (en) 1985-10-28
ZA83955B (en) 1984-09-26
FR2528850B1 (fr) 1985-07-26
SU1189351A3 (ru) 1985-10-30

Similar Documents

Publication Publication Date Title
EP1451189B1 (fr) Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo- 3.2.2]nonane, leur preparation et leur application en therapeutique
FR2663336A1 (fr) Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
SK3898A3 (en) Cyclic gmp-specific phosphodiesterase inhibitors
JP3817256B2 (ja) タキキニンアンタゴニスト
EP0623621A1 (en) Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists
EP0708105B1 (en) 5-HT4 receptor agonists
JP3010558B2 (ja) 新規の1,7‐融合1h‐インドール‐2‐カルボン酸‐n‐(1,4‐ベンゾジアゼピン‐3‐イル)‐アミド、その製法及びこれを含有するコレシストキニン拮抗作用薬剤
US4824861A (en) Pyrrolidone derivatives and memory enhancement use thereof
US4563306A (en) Peptides and process for preparing the same
JPH0259160B2 (hu)
WO1997005129A1 (fr) (r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridine-carboxamide, son procede d'obtention et medicament le contenant
US5834464A (en) Imidazolinobenzodiazepines
JPS58148888A (ja) 麦角アルカロイド類
EP0760362A1 (en) Novel diaminomethylidene derivative
PL80112B1 (hu)
US4737499A (en) Ergotalkaloids for treating senile dementia
US4868313A (en) A process for making pyrrolidone derivatives
JP3251954B2 (ja) アザビシクロ誘導体
WO1993016082A1 (en) 4-oxo- and 4h-imidazo(5,1-c)(1,4)benzoxazines useful as benzodiazepine receptor-binding agents
JPH03176478A (ja) 新規なジケトピペラジン誘導体及びこれを有効成分とする免疫抑制剤
US4609657A (en) Ergot peptide alkaloid derivatives, processes for their preparation and pharmaceutical compositions containing them
JP2003501353A (ja) Nk−1受容体アンタゴニストとしての(2−ベンズヒドリル−1−アザビシクロ[2.2.2]オクト−3−イル)−(5−イソプロピル−2−メトキシベンジル)−アミンクエン酸塩の結晶多形
IL34747A (en) Ergonorcornine,its 1-methyl derivative and their salts,their preparation and pharmaceutical compositions containing them
JP2002504903A (ja) ペンタエリスリトール新規誘導体、その製造及び使用、並びにその合成の為の中間体
JPH07500595A (ja) アザスピラン類を用いる高脂血症の治療方法