JPS58141775A - Filter for tobacco - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a cigarette filter, and particularly to a filter having the effect of inactivating the mutagenicity of tobacco smoke.

The causal relationship between smoking and cancer development is one of the issues that has received epidemiological attention in recent years. This problem.

Despite many years of efforts by many researchers, this is not fully understood, but it is acknowledged that smoking is a trigger for squamous cell carcinoma.

Furthermore, it is clear that cigarette smoke contains carcinogenic substances such as benzpyrene, even in minute amounts, and that it is mutagenic to grass organisms.
It has been demonstrated that a high correlation of ~80% exists.

Therefore, given that cancer deaths are now the leading cause of death in the nation, and that deaths from lung cancer in particular are rapidly increasing, the carcinogenicity of tobacco has been proven. Inactivating the mutagenicity of tobacco has important significance for maintaining the health and well-being of the nation, and there have already been many substances that attenuate or eliminate the mutagenicity of tobacco. Studies have been carried out, and for example, saccharides, tannic acid, n-propyl gallate, pyrocatechol, rutin, krestin, BHT, catechol, pyrocatechol, cabbage extract, etc. are said to be effective, but none of them are effective. These substances are impregnated into the tobacco leaf itself or mixed with the latter, and are not used in a part of the filter as in the present invention.According to the inventor's additional tests, the effectiveness of these substances is relatively low. It is weak and cannot reliably inactivate the mutagenicity of cigarette smoke.

However, as a result of research, the present inventor discovered that oxygen scavengers exhibit a strong inactivating effect on mutagenicity in tobacco smoke. Here, the oxygen scavenger refers to, for example, iron or a substance containing iron as a main component, an ion-containing acid salt, a reducing organic compound, or a substance containing them. It means substances that have the ability to absorb molecules, that is, easily oxidizable substances, such as iron powder, ferrous salts, ferric chloride, iron≠゛lupo2~, ferrous oxide, iron silicon, and sulfite. Examples include salts, acid sulfites, pyrosulfites, dithionites, BHA, BHT, and the like.

Therefore, commercially available oxygen absorbers for food packaging are also useful in practicing the present invention.

The present inventor took tobacco tar as a test sample, and used anti-mutagenicity of various oxygen scavengers, Salmonella, Typhimurium, and TA-100 strains, which had never been tested, as materials for cigarette filters. As a result of testing, it was found that many oxygen scavengers were found to be effective as shown in Table IK below.

This invention is based on the above-mentioned new findings, and the gist of the invention is that an oxygen absorber is present in a cigarette filter.

The oxygen absorber used in the present invention has no effect on tobacco flavor within the usual dosage range, and has recently been widely used for food packaging, so there is no need to worry about side effects. It is.

If the oxygen absorber used is iron-based, in addition to iron powder, F
eSO4, FeCl 2. FeBr2. Fe
(NO3)2. Examples include Fe5(PO4)2 ferrous oxalate, ferrous formate, ferrous acetate, etc. In the case of sulfur-containing salts, these include alkali metal salts such as sodium salts and potassium salts, calcium salts, and magnesium salts. It is used in the form of alkaline earth metal salts such as salts or non-toxic metal or ammonium base salts such as aluminum salts, especially potassium and sodium salts, which have poor water solubility, stability and acceptability as food additives. J that is optimal in terms of gender For example,
For example, K2S03. fG(SO3, K2S45, N
a,,S03 NaH8O3, Na2s2o6Na2S
g04, CaSO3, Ca(H803)2)MgS
o3, A12(OH)4S03. (RH4)ED
3°NH4JISO3, (NH4)2SQo5. (N
H4) 28204 etc. are listed.

Further, when the oxygen scavenger used is a reducing organic compound, examples include BHT, BHA, erythorbate, ascorbate, and strong alkali-treated lignin.

In order to apply the above oxygen scavenger to a cigarette filter, one of the following methods is usually used.

(g) A method of impregnating the support of a cigarette filter with an oxygen scavenger.

(B) A method in which the oxygen scavenger is filled into the filter as it is or supported on a suitable carrier.

The first method is suitable when water-soluble sulfur-containing salts are used, and is also the simplest. The second method can be used regardless of whether the oxygen scavenger is water-soluble or not, but in the case of metal powder such as iron powder, only the pure oxygen scavenger can be used. By the way, absorbent cotton, activated carbon, silica gel, dextrin, starch, alumina, pal
Since adsorbents such as carbon dioxide or cellulose acetate themselves have a huge specific surface area, when the oxygen scavenger is adsorbed onto them, the contact area with tobacco smoke increases, so when the former is present alone - compared to Increased effectiveness. Even metals such as iron can be made into highly active oxygen scavengers by adsorbing them on a carrier in the form of water-soluble salts such as iron chloride and then reducing them. Since the material can be granulated appropriately, it is easy to automate the filter production process. It goes without saying that activated carbon, silica gel, and other arbitrary materials currently used as constituent materials of filters can be incorporated into the filter of the present invention, if necessary.

The oxygen scavenger, which is the main constituent material of the filter of the present invention, is often oxidized by oxygen in the air.

Moisture in the air also often promotes chain oxidation reactions.

Therefore, it is desirable that the cigarette (particularly a rolled cigarette) and the filter attached to the filter of the present invention be packaged with a packaging material that has a high barrier property against oxygen and water vapor. Polycellofilm lined with a gas-resistant plastic such as an ionomer or polyvinylidene chloride is one suitable packaging material for this purpose.

FIG. 1 shows an example in which the present invention is applied to a filter-attached cigarette.

The filter part (2) at the rear of the cigarette f11 is 2
It is composed of unit filters (2B, 2b) of species.

Each unit filter is made by compressing short cellulose acetate fibers, and the front filter (2a) is impregnated with water-soluble sulfite and activated carbon particles (3).
Built-in. The rear unit filter (2b) is a normal acetate filter. The tar content in the smoke generated by smoking is adsorbed by the activated carbon (3) in 2a, and is also brought into contact with sulfite to deactivate its mutagenicity. Of course, if necessary, a section of the filter can be extended or the rear filter layer can be impregnated with sulfite.

Figure 2 shows an example in which the present invention is applied to a pipe-shaped filter separate from a cigarette.
) Inside the front and rear separators with pores +51. (5')
Activated alumina impregnated with sulfites via
6) is filled. As activated alumina is used, it gradually turns brown due to tar, so discard it at an appropriate location.

Hereinafter, embodiments of the invention will be described with reference to Examples, but these are, of course, illustrative and do not imply any limitations on the idea of the invention. Although it is not clear why various oxygen scavengers and oxygen absorbers inactivate the mutagenicity of cigarette smoke as shown in the examples, it is probably because the mutagenic substances in cigarette smoke are inactivated by oxygen. It is believed that this is due to high reactivity.

The mutagenicity and mutagenicity suppressing effect were measured by the brain incubation method (Sugizai, Nagaashi, Chemical Mutagens, Vol. 6, p. 41 (1981)).

Example 1 Aqueous solutions of 2M sodium sulfite, 2M sodium bisulfite, and 1M potassium pyrosulfite, each 0.4-
A filter was made by absorbing this into absorbent cotton filled in a hard plastic tube with one end flattened. This filter was used in an automatic smoking device at Vc, and the long piece was used to smoke at a rate of 2 seconds per minute until the length of the cigarette butt reached 80 m under 85-smoking conditions each time, and the smoke was inhaled through the above filter. Tar in the main stream was collected on a glass fiber filter. Add dimethyl sulfoxide to this tar collection filter,
Tar was extracted, diluted appropriately, and used for assay. The results are shown in Table 1 below. As shown, the mutagenicity of the tar obtained through the above filter has completely disappeared.

° Table 1 Example 2 Experiments similar to those in the previous example were conducted using eight types of commercially available oxygen scavengers. A commercially available "Aqua Filter" was used as the filter, and its contents were taken out and replaced with a test state tax oxygen agent and a control material. The results are shown in the table below.
Shown as 2.

Table-2 Rice Manufactured by Mitsubishi Gas Chemical Co., Ltd. Mirai Toagosei Kagaku Rice manufacturing material Toyo Pulp Manufactured (blank below) Table-3 BHT (dibutylhydroxytoluene) or BHA
(Butylhydroxyaniso-/L/) 1g each,
1.5 cc of a 25% aqueous solution of sodium hydroxide was adsorbed on 5 g of diatomaceous earth powder and mixed to form a powder. Using the obtained powder, an experiment similar to Example 2-b) was conducted.

The results are shown in Table 4 below.

(Margin below) Table-4

[Brief explanation of the drawing]

Fig. 1 is a partially cutaway front view showing an example in which the present invention is applied to a cigarette, and Fig. 2 shows the present invention as a cigarette.1: Cigarette (whole), 2: Part of filter (whole) , 6: Activated carbon particles, 4: Pipe type filter (whole)
, 55: Separator with pores, 6: Activated aluminum. Figure 1 Second circle

Claims (1)

[Claims] , +1 A cigarette filter containing an oxygen absorber. (2) The filter according to claim (1), wherein the oxygen scavenger is sulfite, acid sulfite, pyrosulfite, or dithionite. The filter according to claim 11, which is a monoferrous salt compound. (4) The filter according to claim 1, wherein the oxygen scavenger is a reducing organic compound. 1fii The oxygen scavenger is Claims 1+ to 4 are supported on a carrier such as activated carbon, alumina, silica gene, starch, dextrin, absorbent cotton, cellulose acetate, pulp, diatomaceous earth, powdered gypsum, natural zeolite, or molecular sieve. 6. The filter according to any one of claims (1) to (5), wherein the filter is integrated with a cigarette. (7) The filter is integrated with a cigarette. A filter according to any one of claims 1x) to (6), which is separate from the filter.