JPS5799539A - Preparation of alpha-(p-butylphenyl)-ethyl halide - Google Patents

Preparation of alpha-(p-butylphenyl)-ethyl halide

Info

Publication number
JPS5799539A
JPS5799539A JP17630480A JP17630480A JPS5799539A JP S5799539 A JPS5799539 A JP S5799539A JP 17630480 A JP17630480 A JP 17630480A JP 17630480 A JP17630480 A JP 17630480A JP S5799539 A JPS5799539 A JP S5799539A
Authority
JP
Japan
Prior art keywords
butylphenyl
acid
raw material
ethyl alcohol
butyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17630480A
Other languages
Japanese (ja)
Inventor
Masami Iki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YODOGAWA PHARMA
YODOGAWA SEIYAKU KK
Original Assignee
YODOGAWA PHARMA
YODOGAWA SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YODOGAWA PHARMA, YODOGAWA SEIYAKU KK filed Critical YODOGAWA PHARMA
Priority to JP17630480A priority Critical patent/JPS5799539A/en
Publication of JPS5799539A publication Critical patent/JPS5799539A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the titled compound useful as a raw material for preparing medicines in high purity and yield by an easy operation, by reacting an inexpensive and industrially easily handleable hydrohalogenic acid with an α-(p- butylphenyl)-ethyl alcohol.
CONSTITUTION: An α-(p-butylphenyl)-ethyl alcohol is dissolved in a waterinsoluble solvent, e.g. toluene, diethyl ether or n-hexane, and an excess of hydrohalogenic acid, e.g. 35% hydrochloric acid or hydrobromic acid, is added to the solution and stirred to carry out the halogenation reaction at ordinary temperature or near the ordinary temperature for several hours. Thus, an oily α-(p-butylphenyl)- ethyl halide is obtained quantitatively. The butyl group is n-butyl, isobutyl, secondary or tertiary butyl group.
USE: A raw material for preparing α-(p-isobutylphenyl)-propionic acid which is an anti-inflammatory agent, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP17630480A 1980-12-13 1980-12-13 Preparation of alpha-(p-butylphenyl)-ethyl halide Pending JPS5799539A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17630480A JPS5799539A (en) 1980-12-13 1980-12-13 Preparation of alpha-(p-butylphenyl)-ethyl halide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17630480A JPS5799539A (en) 1980-12-13 1980-12-13 Preparation of alpha-(p-butylphenyl)-ethyl halide

Publications (1)

Publication Number Publication Date
JPS5799539A true JPS5799539A (en) 1982-06-21

Family

ID=16011240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17630480A Pending JPS5799539A (en) 1980-12-13 1980-12-13 Preparation of alpha-(p-butylphenyl)-ethyl halide

Country Status (1)

Country Link
JP (1) JPS5799539A (en)

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