JPS579771A - Tetrazole derivative - Google Patents
Tetrazole derivativeInfo
- Publication number
- JPS579771A JPS579771A JP8425180A JP8425180A JPS579771A JP S579771 A JPS579771 A JP S579771A JP 8425180 A JP8425180 A JP 8425180A JP 8425180 A JP8425180 A JP 8425180A JP S579771 A JPS579771 A JP S579771A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- reaction
- compound
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003536 tetrazoles Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000767 anti-ulcer Effects 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- NDOXXNRGRVISHK-UHFFFAOYSA-N 1-cyclohexyl-5-(3-naphthalen-2-yloxypropyl)tetrazole Chemical compound C=1C=C2C=CC=CC2=CC=1OCCCC1=NN=NN1C1CCCCC1 NDOXXNRGRVISHK-UHFFFAOYSA-N 0.000 abstract 1
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- JUINSXZKUKVTMD-UHFFFAOYSA-N hydrogen azide Chemical compound N=[N+]=[N-] JUINSXZKUKVTMD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8425180A JPS579771A (en) | 1980-06-21 | 1980-06-21 | Tetrazole derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8425180A JPS579771A (en) | 1980-06-21 | 1980-06-21 | Tetrazole derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS579771A true JPS579771A (en) | 1982-01-19 |
| JPH0156067B2 JPH0156067B2 (enrdf_load_stackoverflow) | 1989-11-28 |
Family
ID=13825236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8425180A Granted JPS579771A (en) | 1980-06-21 | 1980-06-21 | Tetrazole derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS579771A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| US5081127A (en) * | 1988-01-07 | 1992-01-14 | E. I. Du Pont De Nemours And Company | Substituted 1,2,3-triazole angiotensin II antagonists |
| US5189048A (en) * | 1988-01-07 | 1993-02-23 | E. I. Du Pont De Nemours And Company | Substituted 1,2,3 triazole angiotensin II antagonists |
| JPH06313491A (ja) * | 1993-04-28 | 1994-11-08 | Toto Ltd | 水 栓 |
| WO2009117888A1 (zh) * | 2008-03-24 | 2009-10-01 | 合肥合源药业有限公司 | 磷酸二酯酶iii抑制剂、其制法及其医疗用途 |
-
1980
- 1980-06-21 JP JP8425180A patent/JPS579771A/ja active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| US5081127A (en) * | 1988-01-07 | 1992-01-14 | E. I. Du Pont De Nemours And Company | Substituted 1,2,3-triazole angiotensin II antagonists |
| US5189048A (en) * | 1988-01-07 | 1993-02-23 | E. I. Du Pont De Nemours And Company | Substituted 1,2,3 triazole angiotensin II antagonists |
| JPH06313491A (ja) * | 1993-04-28 | 1994-11-08 | Toto Ltd | 水 栓 |
| WO2009117888A1 (zh) * | 2008-03-24 | 2009-10-01 | 合肥合源药业有限公司 | 磷酸二酯酶iii抑制剂、其制法及其医疗用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0156067B2 (enrdf_load_stackoverflow) | 1989-11-28 |
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