JPS5797446A - Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom - Google Patents

Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom

Info

Publication number
JPS5797446A
JPS5797446A JP55174001A JP17400180A JPS5797446A JP S5797446 A JPS5797446 A JP S5797446A JP 55174001 A JP55174001 A JP 55174001A JP 17400180 A JP17400180 A JP 17400180A JP S5797446 A JPS5797446 A JP S5797446A
Authority
JP
Japan
Prior art keywords
optical isomer
carbon atom
carboxylic acid
gas chromatography
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55174001A
Other languages
Japanese (ja)
Inventor
Takafumi Oi
Akira Doi
Youko Inda
Masao Horiba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP55174001A priority Critical patent/JPS5797446A/en
Publication of JPS5797446A publication Critical patent/JPS5797446A/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/29—Chiral phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Abstract

PURPOSE:To separate each optical isomer accurately at the same time by a gas chromatography, by using optically active peptide ester as a stationary phase after reacting a mixture of optical isomer of carboxylic acid having an assymetric carbon atom with amine having an NH2 radical connecting directly with the assymetric carbon atom. CONSTITUTION:A mixture of optical isomer of carboxylic acid (including the primary chrysanthemumic acid also) expressed by formulaI[R1, R2, R3 are each different H, halogen, alkyl, cycloalkyl, aryl (substitution) alkyl and a substituent is halogen, OH, acyloxy, SH, acylthio]is reacted with amine having an amino radical expressed by formula II (R4-R6 are each different H, alkyl, cycloalky, aryl) or amino acid ester having the amino radical connecting directly with an assymetric carbon atom, and four kinds of diastereomer amide derivative are made and after that, the optical isomer is separated accurately by a gas chromatography using peptide ester of S-triazine derivatives having two or more of assymetric carbon atoms expressed by formula III as a stationary phase.
JP55174001A 1980-12-09 1980-12-09 Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom Pending JPS5797446A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55174001A JPS5797446A (en) 1980-12-09 1980-12-09 Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55174001A JPS5797446A (en) 1980-12-09 1980-12-09 Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom

Publications (1)

Publication Number Publication Date
JPS5797446A true JPS5797446A (en) 1982-06-17

Family

ID=15970906

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55174001A Pending JPS5797446A (en) 1980-12-09 1980-12-09 Gas chromatography for optical isomer of carboxylic acid having asymmetric carbon atom

Country Status (1)

Country Link
JP (1) JPS5797446A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948395A (en) * 1989-09-12 1990-08-14 Advanced Separations Technologies Inc. Chiral separation media
US5154738A (en) * 1989-09-12 1992-10-13 Advanced Separation Technologies, Inc. Chiral separation media

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948395A (en) * 1989-09-12 1990-08-14 Advanced Separations Technologies Inc. Chiral separation media
US5154738A (en) * 1989-09-12 1992-10-13 Advanced Separation Technologies, Inc. Chiral separation media

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